DE69736387D1 - Biosynthese-verfahren zur herstellung von o-phospho-l-threonine - Google Patents

Biosynthese-verfahren zur herstellung von o-phospho-l-threonine

Info

Publication number
DE69736387D1
DE69736387D1 DE69736387T DE69736387T DE69736387D1 DE 69736387 D1 DE69736387 D1 DE 69736387D1 DE 69736387 T DE69736387 T DE 69736387T DE 69736387 T DE69736387 T DE 69736387T DE 69736387 D1 DE69736387 D1 DE 69736387D1
Authority
DE
Germany
Prior art keywords
biosynthesis
phospho
threonine
preparation
transformed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69736387T
Other languages
English (en)
Other versions
DE69736387T2 (de
Inventor
Francis Blanche
Beatrice Cameron
Joel Crouzet
Laurent Debussche
Denis Thibaut
Elisabeth Remy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9492055&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69736387(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Application granted granted Critical
Publication of DE69736387D1 publication Critical patent/DE69736387D1/de
Publication of DE69736387T2 publication Critical patent/DE69736387T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/42—Cobalamins, i.e. vitamin B12, LLD factor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69736387T 1996-05-13 1997-05-05 Biosynthese-verfahren zur herstellung von o-phospho-l-threonine Expired - Lifetime DE69736387T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9605896 1996-05-13
FR9605896A FR2748492B1 (fr) 1996-05-13 1996-05-13 Procede de biosynthese permettant la preparation de cobalamines
PCT/FR1997/000793 WO1997043421A1 (fr) 1996-05-13 1997-05-05 Procede de biosynthese permettant la preparation de cobalamines

Publications (2)

Publication Number Publication Date
DE69736387D1 true DE69736387D1 (de) 2006-09-07
DE69736387T2 DE69736387T2 (de) 2007-09-13

Family

ID=9492055

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69736387T Expired - Lifetime DE69736387T2 (de) 1996-05-13 1997-05-05 Biosynthese-verfahren zur herstellung von o-phospho-l-threonine

Country Status (16)

Country Link
US (1) US6156545A (de)
EP (1) EP0906430B1 (de)
JP (2) JP4293637B2 (de)
CN (1) CN1148451C (de)
AT (1) ATE334204T1 (de)
AU (1) AU2781297A (de)
CA (1) CA2254717C (de)
DE (1) DE69736387T2 (de)
DK (1) DK0906430T3 (de)
EA (1) EA002588B1 (de)
ES (1) ES2270458T3 (de)
FR (1) FR2748492B1 (de)
HU (1) HU230179B1 (de)
PT (1) PT906430E (de)
SI (1) SI0906430T1 (de)
WO (1) WO1997043421A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2748492B1 (fr) * 1996-05-13 1998-06-19 Rhone Poulenc Rorer Sa Procede de biosynthese permettant la preparation de cobalamines
US6489157B1 (en) * 1999-04-16 2002-12-03 The Government Of The United States Of America As Represented By The Administrator Of The U.S. Environmental Protection Agency Medium for cultivating microorganisms
TWI328612B (en) 2002-07-25 2010-08-11 Dsm Ip Assets Bv Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12
WO2006060898A1 (en) * 2004-12-06 2006-06-15 Aegera Therapeutics Inc Method for treating inflammatory disorders
CN109837320A (zh) * 2019-03-27 2019-06-04 山东泓达生物科技有限公司 一种提高脱氮假单胞杆菌产维生素b12的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2657622B1 (fr) * 1990-01-31 1994-11-25 Rhone Poulenc Sante Polypeptides impliques dans la biosynthese des cobalamines et/ou des cobamides, sequences d'adn codant pour ces polypeptides, procede de preparation, et leur utilisation.
FR2663646B1 (fr) * 1990-06-20 1992-10-09 Rambach Alain Souches de e. coli productrices de vitamine b12 et procede de preparation de la vitamine b12 par culture de ces souches.
EP0647717A1 (de) * 1993-10-06 1995-04-12 Takeda Chemical Industries, Ltd. Verfahren zur Herstellung von Vitamin B12
FR2748492B1 (fr) * 1996-05-13 1998-06-19 Rhone Poulenc Rorer Sa Procede de biosynthese permettant la preparation de cobalamines

Also Published As

Publication number Publication date
CA2254717C (fr) 2012-07-10
JP4293637B2 (ja) 2009-07-08
US6156545A (en) 2000-12-05
WO1997043421A1 (fr) 1997-11-20
EA199801007A1 (ru) 1999-04-29
FR2748492A1 (fr) 1997-11-14
CA2254717A1 (fr) 1997-11-20
PT906430E (pt) 2006-12-29
HUP9902730A3 (en) 2000-03-28
JP2000509992A (ja) 2000-08-08
HUP9902730A2 (hu) 1999-12-28
ES2270458T3 (es) 2007-04-01
DE69736387T2 (de) 2007-09-13
ATE334204T1 (de) 2006-08-15
DK0906430T3 (da) 2006-11-27
CN1218508A (zh) 1999-06-02
EP0906430A1 (de) 1999-04-07
EP0906430B1 (de) 2006-07-26
AU2781297A (en) 1997-12-05
CN1148451C (zh) 2004-05-05
JP2009142289A (ja) 2009-07-02
EA002588B1 (ru) 2002-06-27
SI0906430T1 (sl) 2006-12-31
HU230179B1 (hu) 2015-09-28
FR2748492B1 (fr) 1998-06-19

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