DE69732628D1 - Beta 1-4 n-acetylglucosaminyltransferase sowie das für diese kodierende gen - Google Patents

Beta 1-4 n-acetylglucosaminyltransferase sowie das für diese kodierende gen

Info

Publication number
DE69732628D1
DE69732628D1 DE69732628T DE69732628T DE69732628D1 DE 69732628 D1 DE69732628 D1 DE 69732628D1 DE 69732628 T DE69732628 T DE 69732628T DE 69732628 T DE69732628 T DE 69732628T DE 69732628 D1 DE69732628 D1 DE 69732628D1
Authority
DE
Germany
Prior art keywords
gnt
enzyme
gene
beta
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69732628T
Other languages
English (en)
Other versions
DE69732628T2 (de
Inventor
Suguru Oguri
Mari Minowa
Aruto Yoshida
Naoyuki Taniguchi
Makoto Takeuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kirin Brewery Co Ltd
Original Assignee
Kirin Brewery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery Co Ltd filed Critical Kirin Brewery Co Ltd
Publication of DE69732628D1 publication Critical patent/DE69732628D1/de
Application granted granted Critical
Publication of DE69732628T2 publication Critical patent/DE69732628T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69732628T 1996-12-12 1997-12-10 Beta 1-4 n-acetylglucosaminyltransferase sowie das für diese kodierende gen Expired - Lifetime DE69732628T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP33241196 1996-12-12
JP33241196 1996-12-12
JP16146297 1997-06-18
JP16146297 1997-06-18
PCT/JP1997/004546 WO1998026053A1 (en) 1996-12-12 1997-12-10 NOVEL β1→4 N-ACETYLGLUCOSAMINYLTRANSFERASE AND GENE ENCODING THE SAME

Publications (2)

Publication Number Publication Date
DE69732628D1 true DE69732628D1 (de) 2005-04-07
DE69732628T2 DE69732628T2 (de) 2005-12-29

Family

ID=26487595

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69732628T Expired - Lifetime DE69732628T2 (de) 1996-12-12 1997-12-10 Beta 1-4 n-acetylglucosaminyltransferase sowie das für diese kodierende gen

Country Status (9)

Country Link
US (1) US6338955B2 (de)
EP (1) EP0905232B1 (de)
JP (1) JP4246264B2 (de)
KR (1) KR100325552B1 (de)
CN (1) CN1273586C (de)
AT (1) ATE290068T1 (de)
DE (1) DE69732628T2 (de)
ES (1) ES2235259T3 (de)
WO (1) WO1998026053A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030170864A1 (en) * 2000-05-30 2003-09-11 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6784123B2 (en) * 1998-02-05 2004-08-31 Asm Japan K.K. Insulation film on semiconductor substrate and method for forming same
JP4160652B2 (ja) 1998-05-22 2008-10-01 キリンファーマ株式会社 エンド−β−Ｎ−アセチルグルコサミニダーゼ遺伝子
EP2264177B1 (de) * 1998-12-09 2015-09-30 Phyton Holdings, LLC Glycoprotein mit menschlichem Glycosylierungsbild
AU2001227900A1 (en) * 2000-01-14 2001-07-24 Incyte Genomics, Inc. Drug metabolizing enzymes
AU2001255324A1 (en) * 2000-04-13 2001-10-30 Incyte Genomics, Inc. Drug metabolizing enzymes
US7718644B2 (en) * 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7393652B2 (en) * 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US20060293266A1 (en) * 2000-05-10 2006-12-28 The Trustees Of Columbia Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure
US7879840B2 (en) * 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US20040048780A1 (en) * 2000-05-10 2004-03-11 The Trustees Of Columbia University In The City Of New York Method for treating and preventing cardiac arrhythmia
US6489125B1 (en) * 2000-05-10 2002-12-03 The Trustees Of Columbia University In The City Of New York Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor
US20040229781A1 (en) * 2000-05-10 2004-11-18 Marks Andrew Robert Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
WO2002000879A2 (en) 2000-06-28 2002-01-03 Glycofi, Inc. Methods for producing modified glycoproteins
US8697394B2 (en) 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
US7863020B2 (en) 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
CN100385006C (zh) 2001-01-19 2008-04-30 陶氏化学公司 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法
EP1371732B1 (de) * 2001-02-26 2008-12-31 Toyo Boseki Kabushiki Kaisha Fusionsprotein mit beta-1,2-n-acetylglucosaminyl-transferase-ii-aktivität und herstellungsverfahren dafür
WO2003091402A2 (en) 2002-04-23 2003-11-06 University Of Georgia Research Foundation, Inc. N-ACETYLGLUCOSAMINYLTRANSFERASE Vb CODING SEQUENCE, RECOMBINANT CELLS AND METHODS
US7544678B2 (en) * 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
US7332299B2 (en) 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
AU2004220548A1 (en) 2003-03-07 2004-09-23 The Trustees Of Columbia University, In The City Of New York Type 1 ryanodine receptor-based methods
US8710045B2 (en) * 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) * 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
CA2684370C (en) 2007-04-17 2017-10-17 Plant Research International B.V. Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2789283B2 (ja) * 1992-08-21 1998-08-20 寳酒造株式会社 ヒト糖転移酵素遺伝子

Also Published As

Publication number Publication date
US6338955B2 (en) 2002-01-15
KR100325552B1 (ko) 2002-08-14
EP0905232A1 (de) 1999-03-31
JP4246264B2 (ja) 2009-04-02
WO1998026053A1 (en) 1998-06-18
EP0905232B1 (de) 2005-03-02
ES2235259T3 (es) 2005-07-01
CN1214732A (zh) 1999-04-21
ATE290068T1 (de) 2005-03-15
KR19990082498A (ko) 1999-11-25
DE69732628T2 (de) 2005-12-29
US20010024814A1 (en) 2001-09-27
EP0905232A4 (de) 2002-09-25
CN1273586C (zh) 2006-09-06

Similar Documents

Publication Publication Date Title
DE69732628D1 (de) Beta 1-4 n-acetylglucosaminyltransferase sowie das für diese kodierende gen
WO1994026906A3 (en) Cloned dna encoding a udp-galnac:polypeptide,n-acetylgalactos aminyltransferase
DE59710862D1 (de) Nucleinsäuremoleküle aus pflanzen codierend enzyme, die an der stärkesynthese beteiligt sind
WO2002077165A3 (en) Glycoconjugate synthesis using a pathway-engineered organism
EP1095158A4 (de) Verfahren und materialien zur herstellung von glucosamin
FR2637612B1 (fr) Sequences de nucleotides codant pour une proteine a activite ureasique
BR9813968A (pt) Moléculas de ácido nucléico que codificam proteìnas tendo atividade frutosil transferase e processos para produzir inulina de cadeia longa
BR9815632A (pt) Fragmento de ácido nucléico isolado e método de obtenção do mesmo, gene quimérico, célula hospedeira transformada, método de alteração do nìvel de expressão de uma enzima e produto
WO2000032757A3 (en) Plant vitamin e biosynthetic enzymes
ATE319854T1 (de) Enzymaktive dna moleküle
ATE352626T1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
WO1995015387A3 (en) Nucleic acid sequences encoding a plant cytoplasmic protein involved in fatty acyl-coa metabolism
DK1025211T3 (da) Hyaluronansyntasegen og anvendelser deraf
WO2002074943A3 (fr) Molecules d'acides nuceiques codant une dextrane-saccharase catalysant la synthese de dextrane portant des ramifications de type alpha-1,2 osidiques
DK0990704T3 (da) Ikke-reducerende sacchariddannende enzym, trehalosefrigivende enzym og fremgangsmåde til fremstilling af saccharider under anvendelse af enzymerne
Magee et al. Proteolytic conversion of the molecular forms of bovine milk galactosyltransferase
ATE368736T1 (de) Bakterielle stämme von genus klebsiella und deren gen kodierend für isomaltulose synthase
AU7459987A (en) DNA fragments encoding the chromosomal nucleotide sugar synthetases and glycosyltransferases involved in the biosynthesis of the o-antigen of shigella dysenteriae, recombinant DNA molecules containing said fragments, host organisms containing said recombinant DNA molecules vaccines for preventing bacillary dysentery and method for preventing bacillary dysentery
EP1118667A4 (de) Neuartige enzym zusammensetzungen, verfahren zur und verwendung herstellung derselben
HUP0203221A2 (hu) A lignin bioszintézisében résztvevő enzimeket kódoló gének és alkalmazásuk
AU5727099A (en) A 2,6-beta-d-fructan hydrolase enzyme and processes for using the enzyme
DE59611069D1 (de) Saccharose-Stoffwechsel-Mutanten
ATE73847T1 (de) Dna-fragment mit dem cyclodextrin-glycosyltransferase-strukturgen, expressionsvektor, mikroorganismen zur expression und herstellungsverfahren.
DE69419892D1 (de) Fructosyltransferase, Methode zur Herstellung, und das Enzym kodierende DNA
WO2000037652A3 (en) Flavonoid biosynthetic enzymes

Legal Events

Date Code Title Description
8364 No opposition during term of opposition