DE69724209D1 - Erkennung einer genetischen prädisposition fur osteoporose - Google Patents

Erkennung einer genetischen prädisposition fur osteoporose

Info

Publication number
DE69724209D1
DE69724209D1 DE69724209T DE69724209T DE69724209D1 DE 69724209 D1 DE69724209 D1 DE 69724209D1 DE 69724209 T DE69724209 T DE 69724209T DE 69724209 T DE69724209 T DE 69724209T DE 69724209 D1 DE69724209 D1 DE 69724209D1
Authority
DE
Germany
Prior art keywords
osteoporosis
detection
genetic predisposition
genomic dna
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69724209T
Other languages
English (en)
Other versions
DE69724209T2 (de
Inventor
W Duff
Graham Russell
Richard Eastell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Interleukin Genetics Inc
Original Assignee
Interleukin Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interleukin Genetics Inc filed Critical Interleukin Genetics Inc
Publication of DE69724209D1 publication Critical patent/DE69724209D1/de
Application granted granted Critical
Publication of DE69724209T2 publication Critical patent/DE69724209T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69724209T 1996-04-05 1997-04-03 Erkennung einer genetischen prädisposition fur osteoporose Expired - Lifetime DE69724209T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US628282 1996-04-05
US08/628,282 US5698399A (en) 1996-04-05 1996-04-05 Detecting genetic predisposition for osteoporosis
PCT/US1997/005626 WO1997038135A1 (en) 1996-04-05 1997-04-03 Detecting genetic predisposition for osteoporosis

Publications (2)

Publication Number Publication Date
DE69724209D1 true DE69724209D1 (de) 2003-09-25
DE69724209T2 DE69724209T2 (de) 2004-06-17

Family

ID=24518226

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69724209T Expired - Lifetime DE69724209T2 (de) 1996-04-05 1997-04-03 Erkennung einer genetischen prädisposition fur osteoporose

Country Status (13)

Country Link
US (1) US5698399A (de)
EP (1) EP0832298B1 (de)
CN (1) CN100347313C (de)
AT (1) ATE247718T1 (de)
AU (1) AU712461B2 (de)
CA (1) CA2226223C (de)
DE (1) DE69724209T2 (de)
ES (1) ES2208892T3 (de)
IL (1) IL122808A (de)
MX (1) MX9800192A (de)
NZ (1) NZ329530A (de)
WO (1) WO1997038135A1 (de)
ZA (1) ZA972909B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998137A (en) * 1996-01-17 1999-12-07 Grainger; David J. Methods of diagnosis by detecting polymorphisms in the TGF-β1 promoter
GB9608133D0 (en) * 1996-04-19 1996-06-26 Gemini International Holdings Diagnostic method and apparatus
US6203993B1 (en) 1996-08-14 2001-03-20 Exact Science Corp. Methods for the detection of nucleic acids
US6300077B1 (en) 1996-08-14 2001-10-09 Exact Sciences Corporation Methods for the detection of nucleic acids
GB9621129D0 (en) 1996-10-10 1996-11-27 Duff Gordon W Detecting genetic predisposition to sight-threatening diabetic retinopathy
US6524795B1 (en) * 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
US7820383B2 (en) * 1997-03-10 2010-10-26 Interleukin Genetics, Inc. Method for diagnosing myocardial infarction
US6210877B1 (en) * 1997-03-10 2001-04-03 Interleukin Genetics, Inc. Prediction of coronary artery disease
US6720141B1 (en) * 1999-11-01 2004-04-13 Interleukin Genetics, Inc. Diagnostics and therapeutics for restenosis
GB9706359D0 (en) * 1997-03-27 1997-05-14 Gemini International Holdings Polymorphisms of an il-1 receptor antagonist gene
EP0977893A1 (de) * 1997-04-23 2000-02-09 Abbott Laboratories Reagentien und verfahren zur erkennung von prostataerkrankungen
US20050282198A1 (en) * 1997-05-29 2005-12-22 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype
GB9711040D0 (en) * 1997-05-29 1997-07-23 Duff Gordon W Prediction of inflammatory disease
US20050032077A1 (en) * 1998-03-10 2005-02-10 Duff Gordon W. Detecting genetic predisposition to sight-threatening diabetic retinopathy
AU769949B2 (en) * 1998-04-21 2004-02-12 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
US6733967B1 (en) 1998-04-21 2004-05-11 Interleukin Genetics, Inc. Fetal testing for prediction of low birth weight
CA2331254A1 (en) * 1998-06-16 1999-12-23 Exact Laboratories, Inc. Methods for the detection of nucleic acids
AUPP547398A0 (en) * 1998-08-26 1998-09-17 Medvet Science Pty. Ltd. Predictive assessment of certain skeletal disorders
EP1114181A2 (de) * 1998-09-15 2001-07-11 Signalgene Inc. Kombination von östrogen- und vitamin d-rezeptor-gen-markern oder äquivalenten davon zur prognose einer osteoporose therapie-antwort
AU2587500A (en) * 1998-11-30 2000-06-19 Drexel University Methods and kits for identifying individuals at risk of developing osteoporosis
US6762023B1 (en) 1998-11-30 2004-07-13 Drexel University Methods for identifying individuals at risk of developing osteoporosis
CA2378221A1 (en) * 1999-06-30 2001-01-04 Interleukin Genetics, Inc. Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplotype
US20090023147A1 (en) * 1999-08-30 2009-01-22 Kenneth Kornman Diagnostics and therapeutics for osteoporosis
JP2004504802A (ja) * 1999-08-30 2004-02-19 インターロイキン・ジェネティクス・インコーポレーテッド 骨粗鬆症の診断および療法
AU2001257071A1 (en) * 2000-04-17 2001-10-30 Oregon Health & Science University Ext2 as a predictive marker for osteoporosis
WO2002000933A2 (en) * 2000-06-23 2002-01-03 Interleukin Genetics, Inc. Screening assays for identifying modulators of the inflammatory or immune responses
CA2450809A1 (en) * 2001-06-15 2002-12-27 Interleukin Genetics, Inc. Methods for detecting and treating the early onset of aging-related conditions
GB2381526A (en) * 2001-11-03 2003-05-07 Sequenom Inc Detection of predisposition to osteoporosis
US20080311581A1 (en) * 2001-11-19 2008-12-18 David Wyllie Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases
EP1463745A4 (de) * 2001-11-19 2007-11-07 Interleukin Genetics Inc Sich auf die transkription sowie die anfälligkeit gegenüber entzündungs- und infektionskrankheiten auswirkende funktionspolymorphismen des interleukin-1-locus
US20030148288A1 (en) * 2002-02-01 2003-08-07 Yi-Wei Tang Colorimetric genetic test for clinically significant TNF polymorphism and methods of use thereof
US20030198316A1 (en) * 2002-04-17 2003-10-23 Piet Dewaele Osteoporosis screening method
US20040229228A1 (en) * 2002-07-25 2004-11-18 Northwestern University Il-1 genotype in early kidney allograft rejection
CN100453650C (zh) * 2002-09-30 2009-01-21 诺瓦提斯公司 预测免疫抑制治疗期间胆固醇升高的方法
GB0301715D0 (en) * 2003-01-24 2003-02-26 King S College London Detection of predisposition to osteoporosis
JP2007501627A (ja) * 2003-08-08 2007-02-01 インタールーキン ジェネティックス インク 骨粗鬆症のための診断法および治療法
US20090170105A1 (en) * 2007-11-08 2009-07-02 Interleukin Genetics, Inc. Diagnostics for Aging-Related Dermatologic Disorders
US20100098775A1 (en) 2008-05-02 2010-04-22 Interleukin Genetics, Inc. Detecting genetic predisposition to osteoarthritis associated conditions
EP2304052A2 (de) * 2008-05-02 2011-04-06 Interleukin Genetics, Inc. Nachweis von genetischer veranlagung für osteoarthritische erkrankungen
US10894985B2 (en) 2016-01-12 2021-01-19 Sitokine Limited Methods for predicting response to treatment
US10329620B2 (en) 2017-01-12 2019-06-25 Cardioforecast Ltd. Methods and kits for treating cardiovascular disease
EP3536853A1 (de) 2018-03-06 2019-09-11 Lenzing Aktiengesellschaft Lyocellfaser mit verringerter pillenbildung
US20220249660A1 (en) 2019-06-06 2022-08-11 Sitokine Limited Compositions and methods for treating lung, colorectal and breast cancer
WO2021028469A1 (en) 2019-08-12 2021-02-18 Sitokine Limited Compositions and methods for treating cytokine release syndrome and neurotoxicity
WO2021205013A1 (en) 2020-04-09 2021-10-14 Sitokine Limited Compositions and methods for treating covid-19

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064851A (en) * 1990-07-24 1991-11-12 Pfizer Inc. 3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use
JP3465903B2 (ja) * 1992-07-31 2003-11-10 ガーヴァン インスティチュート オブ メディカル リサーチ 作動因子における対立遺伝子の変動の評価
IT1269989B (it) * 1994-09-21 1997-04-16 Dompe Spa Antagonisti recettoriali di il-1 ad aumentata attivita' inibitoria

Also Published As

Publication number Publication date
US5698399A (en) 1997-12-16
CA2226223C (en) 2001-11-20
EP0832298A1 (de) 1998-04-01
CN100347313C (zh) 2007-11-07
EP0832298B1 (de) 2003-08-20
MX9800192A (es) 1998-11-30
ES2208892T3 (es) 2004-06-16
CA2226223A1 (en) 1997-10-16
IL122808A (en) 2000-08-31
ATE247718T1 (de) 2003-09-15
DE69724209T2 (de) 2004-06-17
EP0832298A4 (de) 1999-09-08
WO1997038135A1 (en) 1997-10-16
NZ329530A (en) 1999-10-28
IL122808A0 (en) 1998-08-16
AU712461B2 (en) 1999-11-04
ZA972909B (en) 1998-10-26
AU2607797A (en) 1997-10-29
CN1194668A (zh) 1998-09-30

Similar Documents

Publication Publication Date Title
DE69724209D1 (de) Erkennung einer genetischen prädisposition fur osteoporose
Pemberton et al. Nonamplifying alleles at microsatellite loci: a caution for parentage and population studies
AU8132194A (en) Single nucleotide polymorphisms and their use in genetic analysis
GB9811526D0 (en) Early entry PCT
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
ATE224456T1 (de) Detektion einer genetischen prädisposition für diabetische retinopathie mit dem risiko des verlusts der sehkraft
CA2300355A1 (en) Detection of genetic alterations of chromosome 20q that are associated with breast cancer
ATE319856T1 (de) Verfahren zur erkennung von genpolymorphismen und allelexpression unter verwendung von sondenchips
EP1290220A4 (de) Genetische diagnose zur feststellung von unerwünschten reaktionen auf arzneimittel gegen qt verlängerung
CY1108771T1 (el) Μεταλλαξη εντος του γονιδιου κοννεξινης 26 υπευθυνου για προγλωσσικη μη-συνδρομικη κωφωση και μεθοδος ανιχνευσης
ES2150103T3 (es) Oligonucleotidos de amplificacion de acido nucleico y sondas para borrelia asociados con la enfermedad de lyme.
ES2175095T3 (es) Marcadores de adn respecto al tamaño de una camada de cerdos.
ATE359374T1 (de) Verfahren zur diagnose der erblichen hemochromatosis
DE69710469D1 (de) Diagnoseverfahren und vorrichtung zum nachweis der prädisposition zu bestimmten krankheitszuständen, insbesondere osteoporose, auf basis von il-6 genpolymorphismus
ES2308852T3 (es) Secuencias genomicas y completas de cdna de apm1 humano especifico para adipocitos y marcadores bialelicos de los mismos.
Zhao et al. Microsatellite markers from a microdissected swine chromosome 6 genomic library
US20080044916A1 (en) Computational selection of probes for localizing chromosome breakpoints
WO1999002735A3 (en) Diagnostic assays and kits for body mass and cardiovascular disorders
DE69930826D1 (de) Hybridisierungsnachweisverfahren unter Verwendung von Biochips
WO1999002736A3 (en) Sr-bi nucleic acids and uses therefor
WO1999066077A3 (en) Methods for the detection of nucleic acids
Ohsumi et al. Loss of Heterozygosity in Chromosome-1, Chromosome-5, Chromosome-7 and Chromosome-13 in Mouse Hepatoma Detected by Systematic Genome-Wide Scanning Using Rlgs Genetic-Map
DE69500393T2 (de) Verfahren zur identifizierung von lymphozyten mit mutator-phänotypen
AU2514999A (en) Mood disorder gene
SE9403170D0 (sv) Process for nucleic acid hybridisation analysis