DE69719815D1 - Aminoacyl sulfamiden zur behandlung hyperproliferativer störungen - Google Patents

Aminoacyl sulfamiden zur behandlung hyperproliferativer störungen

Info

Publication number
DE69719815D1
DE69719815D1 DE69719815T DE69719815T DE69719815D1 DE 69719815 D1 DE69719815 D1 DE 69719815D1 DE 69719815 T DE69719815 T DE 69719815T DE 69719815 T DE69719815 T DE 69719815T DE 69719815 D1 DE69719815 D1 DE 69719815D1
Authority
DE
Germany
Prior art keywords
sulfamides
aminoacyl
hyperproliferative disorders
treating hyperproliferative
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69719815T
Other languages
English (en)
Other versions
DE69719815T2 (de
Inventor
M Hill
F Kluge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cubist Pharmaceuticals LLC
Original Assignee
Cubist Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cubist Pharmaceuticals LLC filed Critical Cubist Pharmaceuticals LLC
Application granted granted Critical
Publication of DE69719815D1 publication Critical patent/DE69719815D1/de
Publication of DE69719815T2 publication Critical patent/DE69719815T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69719815T 1997-03-18 1997-12-18 Aminoacyl sulfamiden zur behandlung hyperproliferativer störungen Expired - Fee Related DE69719815T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/820,249 US5824657A (en) 1997-03-18 1997-03-18 Aminoacyl sulfamides for the treatment of hyperproliferative disorders
PCT/US1997/023350 WO1998041215A1 (en) 1997-03-18 1997-12-18 Aminoacyl sulfamides for the treatment of hyperproliferative disorders

Publications (2)

Publication Number Publication Date
DE69719815D1 true DE69719815D1 (de) 2003-04-17
DE69719815T2 DE69719815T2 (de) 2003-08-28

Family

ID=25230298

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69719815T Expired - Fee Related DE69719815T2 (de) 1997-03-18 1997-12-18 Aminoacyl sulfamiden zur behandlung hyperproliferativer störungen

Country Status (6)

Country Link
US (1) US5824657A (de)
EP (1) EP0991412B1 (de)
AU (1) AU5899798A (de)
DE (1) DE69719815T2 (de)
ES (1) ES2189993T3 (de)
WO (1) WO1998041215A1 (de)

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* Cited by examiner, † Cited by third party
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ZA9756B (en) * 1996-01-16 1997-07-17 Warner Lambert Co Process for preparing 4,6-disubstituted pyrido[3,4-d]-pyrimidines
ES2229510T3 (es) * 1997-06-27 2005-04-16 Fujisawa Pharmaceutical Co., Ltd. Derivados de anillo aromatico.
US5939458A (en) * 1997-09-22 1999-08-17 Henry; James P. Reduction of hair growth
US6153645A (en) * 1998-09-18 2000-11-28 Cubist Pharmaceuticals, Inc. Heterocycles as antimicrobial agents
GB9822241D0 (en) * 1998-10-12 1998-12-09 Smithkline Beecham Plc Novel compounds
US6329344B1 (en) * 1998-10-22 2001-12-11 Ranbaxy Laboratories Limited Derivatives of monosaccharides as cell adhesion inhibitors
US6602274B1 (en) 1999-01-15 2003-08-05 Light Sciences Corporation Targeted transcutaneous cancer therapy
US6454789B1 (en) 1999-01-15 2002-09-24 Light Science Corporation Patient portable device for photodynamic therapy
US6624187B1 (en) 2000-06-12 2003-09-23 Health Research, Inc. Long wave length absorbing bacteriochlorin alkyl ether analogs
AU2003225085A1 (en) * 2002-04-19 2003-11-03 California Institute Of Technology Unnatural amino acid containing display libraries
EP1619947A4 (de) * 2003-05-01 2006-05-31 Replidyne Inc Antibakterielle verfahren und zusammensetzungen
CA2596424C (en) * 2005-02-04 2016-03-29 Millennium Pharmaceuticals, Inc. Inhibitors of e1 activating enzymes
US8461128B2 (en) 2005-04-15 2013-06-11 Sloan-Kettering Institute For Cancer Research Anti-microbial agents and uses thereof
WO2007067559A2 (en) * 2005-12-06 2007-06-14 Regents Of The University Of Minnesota Antibacterial agents
KR101450535B1 (ko) * 2006-02-02 2014-10-14 밀레니엄 파머슈티컬스 인코퍼레이티드 E1 활성화 효소의 억제제
CN104016987A (zh) 2009-05-14 2014-09-03 米伦纽姆医药公司 氨基磺酸((1s,2s,4r)-4-{4-[(1s)-2,3-二氢-1h-茚-1-基氨基]-7h-吡咯并[2,3-d]嘧啶-7-基}-2-羟基环戊基)甲酯盐酸盐
CN104177361B (zh) * 2014-08-25 2016-03-30 合肥工业大学 一种基于植物生长素调节基因gh3的asa型酶抑制剂及其制备方法
KR102568859B1 (ko) 2015-02-13 2023-08-21 옥스포드 드러그 디자인 리미티드 아미노아실-tRNA 합성효소 저해제로서 신규한 N-아실-아릴술폰아미드 유도체
WO2016201374A1 (en) * 2015-06-11 2016-12-15 University Of Florida Research Foundation, Incorporated Sulfanide adenosine derivatives and uses thereof
GB201617064D0 (en) 2016-10-07 2016-11-23 Inhibox Limited And Latvian Institute Of Organic Synthesis The Compounds and their therapeutic use

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB815381A (en) * 1955-04-27 1959-06-24 American Cyanamid Co Antibiotic designated nucleocidin and preparation thereof
US2914525A (en) * 1957-03-18 1959-11-24 American Cyanamid Co Nucleocidin and the process of obtaining the same
US3854480A (en) * 1969-04-01 1974-12-17 Alza Corp Drug-delivery system
US3622561A (en) * 1969-08-18 1971-11-23 Univ Utah Nucleoside sugar esters of sulfamic acid and method for preparation of the same
US3928319A (en) * 1971-06-16 1975-12-23 Syntex Inc 4 -Fluoro nucleosides, novel intermediates and methods of preparing same
US3817978A (en) * 1971-06-16 1974-06-18 Syntex Inc 4-fluoro nucleosides and sugar intermediates, and methods of preparing
JPS57206397A (en) * 1981-04-10 1982-12-17 Teruhiko Beppu Preparation of antibiotic substance at-265 and/or at-265-b
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
JPS6256500A (ja) * 1985-09-05 1987-03-12 Rikagaku Kenkyusho アスカマイシンの合成法
JPS62108896A (ja) * 1985-11-05 1987-05-20 Rikagaku Kenkyusho アスカマイシンの合成法
JPS62108897A (ja) * 1985-11-05 1987-05-20 Rikagaku Kenkyusho アスカマイシン誘導体及びその合成法並びに制癌剤
JPS6351398A (ja) * 1986-08-22 1988-03-04 Kureha Chem Ind Co Ltd 5′−スルフアモイル−2−ブロモアデノシン及びその製造法
US5039660A (en) * 1988-03-02 1991-08-13 Endocon, Inc. Partially fused peptide pellet
US5470967A (en) * 1990-04-10 1995-11-28 The Dupont Merck Pharmaceutical Company Oligonucleotide analogs with sulfamate linkages
DE4215738A1 (de) * 1991-05-16 1993-02-04 Ciba Geigy Ag Mikroorganismus
JPH0560479A (ja) * 1991-09-02 1993-03-09 Fujikura Ltd ループ型ヒートパイプの製造方法
IL108523A0 (en) * 1993-02-03 1994-05-30 Gensia Inc Pharmaceutical compositions containing adenosine kinase inhibitors for preventing or treating conditions involving inflammatory responses and pain
GB9325810D0 (en) * 1993-12-17 1994-02-23 Zeneca Ltd Herbicidal composition
GB9325809D0 (en) * 1993-12-17 1994-02-23 Zeneca Ltd Herbicidal composition
US5594015A (en) * 1994-06-22 1997-01-14 Regents Of The University Of California Thiazolidine derivatives for the treatment of psoriasis

Also Published As

Publication number Publication date
EP0991412B1 (de) 2003-03-12
WO1998041215A1 (en) 1998-09-24
EP0991412A1 (de) 2000-04-12
US5824657A (en) 1998-10-20
AU5899798A (en) 1998-10-12
ES2189993T3 (es) 2003-07-16
EP0991412A4 (de) 2000-06-21
DE69719815T2 (de) 2003-08-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee