DE69714279D1 - Verfahren zur Herstellung eines Zwischenprodukts in der Cisapridsynthese - Google Patents
Verfahren zur Herstellung eines Zwischenprodukts in der CisapridsyntheseInfo
- Publication number
- DE69714279D1 DE69714279D1 DE69714279T DE69714279T DE69714279D1 DE 69714279 D1 DE69714279 D1 DE 69714279D1 DE 69714279 T DE69714279 T DE 69714279T DE 69714279 T DE69714279 T DE 69714279T DE 69714279 D1 DE69714279 D1 DE 69714279D1
- Authority
- DE
- Germany
- Prior art keywords
- fluorophenoxy
- cis
- methoxy
- propyl
- cisapride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96202860 | 1996-10-15 | ||
PCT/EP1997/005692 WO1998016511A1 (en) | 1996-10-15 | 1997-10-09 | Synthesis of cisapride |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69714279D1 true DE69714279D1 (de) | 2002-08-29 |
DE69714279T2 DE69714279T2 (de) | 2003-03-06 |
Family
ID=8224493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69714279T Expired - Fee Related DE69714279T2 (de) | 1996-10-15 | 1997-10-09 | Verfahren zur Herstellung eines Zwischenprodukts in der Cisapridsynthese |
Country Status (12)
Country | Link |
---|---|
US (1) | US6218542B1 (de) |
EP (1) | EP0934272B1 (de) |
JP (1) | JP2001501960A (de) |
KR (1) | KR100469030B1 (de) |
CN (1) | CN1135222C (de) |
AT (1) | ATE221049T1 (de) |
AU (1) | AU5050098A (de) |
CA (1) | CA2263692C (de) |
DE (1) | DE69714279T2 (de) |
ES (1) | ES2180032T3 (de) |
WO (1) | WO1998016511A1 (de) |
ZA (1) | ZA979194B (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100336400B1 (ko) * | 2000-03-29 | 2002-05-13 | 김건복 | 시사프라이드의 제조 방법 |
KR20100026641A (ko) * | 2008-09-01 | 2010-03-10 | 동아제약주식회사 | 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PH19942A (en) | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
CA1192218A (en) * | 1981-09-16 | 1985-08-20 | Zeneca Ag Products Inc. | Isomer enrichment process for cyclopropanecarboxylates |
CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
US4962115A (en) * | 1981-10-01 | 1990-10-09 | Janssen Pharmaceutica N.V. | Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
US5137896A (en) * | 1981-10-01 | 1992-08-11 | Janssen Pharmaceutica N.V. | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
US5057525A (en) * | 1981-10-01 | 1991-10-15 | Janssen Pharmaceutica N.V. | Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives |
ES2002640A6 (es) * | 1987-03-11 | 1988-09-01 | Alonga Lab | Procedimiento de obtencion de un derivado del acido-4-amino-5-cloro-2-metoxibenzoico |
US5047581A (en) * | 1989-08-25 | 1991-09-10 | Fmc Corporation | Isolation of cis-isomers from isomeric mixtures of cis/transcyclopropanecarboxylates |
AU4666393A (en) * | 1992-07-07 | 1994-01-31 | Sepracor, Inc. | Methods of using (-) cisapride for the treatment of gastro-esophageal reflux disease and other disorders |
EP1170010A3 (de) * | 1992-07-07 | 2004-05-19 | Sepracor Inc. | Verfahren zur Verwendung von (+) -Cisaprid zur Behandlung der Reflux-Ösophagitisund anderer Erkrankungen |
US5712293A (en) * | 1995-06-07 | 1998-01-27 | Sepracor, Inc. | Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride |
US5739151A (en) * | 1996-07-19 | 1998-04-14 | Sepracor Inc. | Method for treating emesis and central nervous system disorders using optically pure (+) norcisapride |
-
1997
- 1997-10-09 JP JP10518028A patent/JP2001501960A/ja active Pending
- 1997-10-09 EP EP97913145A patent/EP0934272B1/de not_active Expired - Lifetime
- 1997-10-09 WO PCT/EP1997/005692 patent/WO1998016511A1/en active IP Right Grant
- 1997-10-09 DE DE69714279T patent/DE69714279T2/de not_active Expired - Fee Related
- 1997-10-09 US US09/284,513 patent/US6218542B1/en not_active Expired - Fee Related
- 1997-10-09 CA CA002263692A patent/CA2263692C/en not_active Expired - Fee Related
- 1997-10-09 ES ES97913145T patent/ES2180032T3/es not_active Expired - Lifetime
- 1997-10-09 AU AU50500/98A patent/AU5050098A/en not_active Abandoned
- 1997-10-09 AT AT97913145T patent/ATE221049T1/de not_active IP Right Cessation
- 1997-10-09 CN CNB971987475A patent/CN1135222C/zh not_active Expired - Fee Related
- 1997-10-09 KR KR10-1999-7001350A patent/KR100469030B1/ko not_active IP Right Cessation
- 1997-10-14 ZA ZA979194A patent/ZA979194B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2263692A1 (en) | 1998-04-23 |
ES2180032T3 (es) | 2003-02-01 |
CA2263692C (en) | 2004-06-22 |
JP2001501960A (ja) | 2001-02-13 |
DE69714279T2 (de) | 2003-03-06 |
ZA979194B (en) | 1999-04-14 |
KR100469030B1 (ko) | 2005-01-31 |
CN1135222C (zh) | 2004-01-21 |
WO1998016511A1 (en) | 1998-04-23 |
KR20000035794A (ko) | 2000-06-26 |
ATE221049T1 (de) | 2002-08-15 |
US6218542B1 (en) | 2001-04-17 |
CN1233240A (zh) | 1999-10-27 |
EP0934272B1 (de) | 2002-07-24 |
EP0934272A1 (de) | 1999-08-11 |
AU5050098A (en) | 1998-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |