ATE99925T1 - Verfahren zur herstellung eines ranitidin-harzabsorbates. - Google Patents
Verfahren zur herstellung eines ranitidin-harzabsorbates.Info
- Publication number
- ATE99925T1 ATE99925T1 AT90312263T AT90312263T ATE99925T1 AT E99925 T1 ATE99925 T1 AT E99925T1 AT 90312263 T AT90312263 T AT 90312263T AT 90312263 T AT90312263 T AT 90312263T AT E99925 T1 ATE99925 T1 AT E99925T1
- Authority
- AT
- Austria
- Prior art keywords
- resin
- ranitidine
- absorbate
- preparing
- adsorbate
- Prior art date
Links
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 title abstract 4
- 229960000620 ranitidine Drugs 0.000 title abstract 4
- 239000011347 resin Substances 0.000 title abstract 4
- 229920005989 resin Polymers 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002156 adsorbate Substances 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 235000019658 bitter taste Nutrition 0.000 abstract 1
- 239000003729 cation exchange resin Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Phenolic Resins Or Amino Resins (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Glass Compositions (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898925484A GB8925484D0 (en) | 1989-11-10 | 1989-11-10 | Process |
| EP90312263A EP0431759B1 (de) | 1989-11-10 | 1990-11-09 | Verfahren zur Herstellung eines Ranitidin-Harz-Absorbates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99925T1 true ATE99925T1 (de) | 1994-01-15 |
Family
ID=10666117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90312263T ATE99925T1 (de) | 1989-11-10 | 1990-11-09 | Verfahren zur herstellung eines ranitidin-harzabsorbates. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0431759B1 (de) |
| JP (1) | JPH03206037A (de) |
| AT (1) | ATE99925T1 (de) |
| AU (1) | AU6652790A (de) |
| CA (1) | CA2029667A1 (de) |
| DE (1) | DE69005993T2 (de) |
| DK (1) | DK0431759T3 (de) |
| ES (1) | ES2047864T3 (de) |
| GB (1) | GB8925484D0 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9104042D0 (en) * | 1991-02-26 | 1991-04-10 | Abbott Lab | Taste-masked buflomedil preparation |
| US20020031490A1 (en) * | 2000-07-27 | 2002-03-14 | Bellamy Simon Andrew | Method for preparing resinates |
| CN1615156B (zh) * | 2002-01-18 | 2012-05-30 | 罗门哈斯公司 | 制备树脂酸酯的方法 |
| GR1009069B (el) * | 2015-01-05 | 2017-07-07 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαρμοσμενης Ερευνας & Αναπτυξης Α.Ε. | Ποσιμα διαλυματα υψηλης συγκεντρωσης που περιεχουν υδροχλωρικη ρανιτιδινη |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB838952A (en) * | 1957-10-03 | 1960-06-22 | Clinical Products Ltd | Resin-drug compounds |
| FR1335502A (fr) * | 1960-06-02 | 1963-08-23 | Merck & Co Inc | Nouveaux composés d'adsorption de la nicotinamide |
| DE2246037B2 (de) * | 1972-09-20 | 1975-02-27 | Taeschner & Co, 8831 Kipfenberg | Peroral anwendbares Arzneimittel mit verzögerter Resorbierbarkeit in Suspensionsform |
| GB1462356A (en) * | 1973-07-10 | 1977-01-26 | Beecham Group Ltd | Pharmaceutical compositions |
| GB8629781D0 (en) * | 1986-12-12 | 1987-01-21 | Glaxo Group Ltd | Pharmaceutical compositions |
| IL90245A (en) * | 1988-05-11 | 1994-04-12 | Glaxo Group Ltd | Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it |
-
1989
- 1989-11-10 GB GB898925484A patent/GB8925484D0/en active Pending
-
1990
- 1990-11-09 CA CA002029667A patent/CA2029667A1/en not_active Abandoned
- 1990-11-09 JP JP2305883A patent/JPH03206037A/ja active Pending
- 1990-11-09 AU AU66527/90A patent/AU6652790A/en not_active Abandoned
- 1990-11-09 DE DE90312263T patent/DE69005993T2/de not_active Expired - Fee Related
- 1990-11-09 ES ES90312263T patent/ES2047864T3/es not_active Expired - Lifetime
- 1990-11-09 DK DK90312263.8T patent/DK0431759T3/da active
- 1990-11-09 AT AT90312263T patent/ATE99925T1/de not_active IP Right Cessation
- 1990-11-09 EP EP90312263A patent/EP0431759B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2029667A1 (en) | 1991-05-11 |
| DE69005993T2 (de) | 1994-05-05 |
| EP0431759A1 (de) | 1991-06-12 |
| AU6652790A (en) | 1991-05-16 |
| DE69005993D1 (de) | 1994-02-24 |
| JPH03206037A (ja) | 1991-09-09 |
| EP0431759B1 (de) | 1994-01-12 |
| GB8925484D0 (en) | 1989-12-28 |
| ES2047864T3 (es) | 1994-03-01 |
| DK0431759T3 (da) | 1994-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |