DE60109494D1 - Verfahren zur herstellung von salbutamolisomeren - Google Patents

Verfahren zur herstellung von salbutamolisomeren

Info

Publication number
DE60109494D1
DE60109494D1 DE60109494T DE60109494T DE60109494D1 DE 60109494 D1 DE60109494 D1 DE 60109494D1 DE 60109494 T DE60109494 T DE 60109494T DE 60109494 T DE60109494 T DE 60109494T DE 60109494 D1 DE60109494 D1 DE 60109494D1
Authority
DE
Germany
Prior art keywords
salbutamol
precursor
optically
optically pure
salbutamolisomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60109494T
Other languages
English (en)
Other versions
DE60109494T2 (de
Inventor
Yusuf Khwaja Hamied
Rajendra Narayanrao Kankan
Ramachandra Rao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9904845&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60109494(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cipla Ltd filed Critical Cipla Ltd
Application granted granted Critical
Publication of DE60109494D1 publication Critical patent/DE60109494D1/de
Publication of DE60109494T2 publication Critical patent/DE60109494T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/34—Preparation of optical isomers by separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60109494T 2000-12-11 2001-12-10 Verfahren zur herstellung von salbutamolisomeren Expired - Lifetime DE60109494T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0030171.3A GB0030171D0 (en) 2000-12-11 2000-12-11 Process for preparing isomers of salbutamol
GB0030171 2000-12-11
PCT/GB2001/005444 WO2002048090A1 (en) 2000-12-11 2001-12-10 Process for preparing isomers of salbutamol

Publications (2)

Publication Number Publication Date
DE60109494D1 true DE60109494D1 (de) 2005-04-21
DE60109494T2 DE60109494T2 (de) 2005-08-04

Family

ID=9904845

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60109494T Expired - Lifetime DE60109494T2 (de) 2000-12-11 2001-12-10 Verfahren zur herstellung von salbutamolisomeren

Country Status (11)

Country Link
US (3) USRE43844E1 (de)
EP (1) EP1349828B1 (de)
AT (1) ATE291006T1 (de)
AU (1) AU2002220918A1 (de)
CA (1) CA2431400C (de)
DE (1) DE60109494T2 (de)
ES (1) ES2240335T3 (de)
GB (1) GB0030171D0 (de)
HK (1) HK1060345A1 (de)
PT (1) PT1349828E (de)
WO (1) WO2002048090A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0030171D0 (en) 2000-12-11 2001-01-24 Cipla Ltd Process for preparing isomers of salbutamol
ATE324364T1 (de) 2002-12-10 2006-05-15 Sepracor Inc Verwendung vom l-tartrat levalbuterolsalz in der herstellung eines dosierinhalators
EP1684593A4 (de) * 2003-11-20 2010-02-10 Alteragon Pty Ltd Verfahren zur verringerung von fettablagerungen sowie des körpergewichts bei säugetieren und vögeln
EP1747189A1 (de) 2004-05-20 2007-01-31 Teva Pharmaceutical Fine Chemicals S.R.L. Herstellung von levalbuterolhydrochlorid
AU2005281511B2 (en) * 2004-09-09 2011-03-31 Cipla Limited Pharmaceutical composition comprising an isomer of a betamimetic agent and an anti-cholinergic agent
RU2440972C2 (ru) * 2004-12-17 2012-01-27 Сипла Лимитед Кристаллический сульфат левосальбутамола, способ его получения и фармацевтическая композиция, содержащая его
MX2007007378A (es) * 2004-12-17 2007-08-14 Cipla Ltd Compuestos y composiciones farmaceuticas.
TW200740779A (en) 2005-07-22 2007-11-01 Mitsubishi Pharma Corp Intermediate compound for synthesizing pharmaceutical agent and production method thereof
EP2099740B1 (de) 2006-08-02 2013-08-14 Aarti Healthcare Limited Verfahren zur herstellung von optisch reinem r-(-)-salbutamol und dessen pharmazeutisch unbedenklichen salzen
EP1935872A1 (de) * 2006-12-11 2008-06-25 Stirling Products Limited Verfahren zur Gewinnung des R-Enantiomers von Salbutamol
BRPI0907222A2 (pt) * 2008-01-15 2015-07-14 Targacept Inc Preparação e separação enantiomérica de 7-(3-piridinil)-1,7-diazaspiro[4-4]nonano e novas formas salinas do racemato e enantiômeros
CN102260179A (zh) * 2010-05-24 2011-11-30 苏州睿克气雾医药有限公司 硫酸沙丁胺醇拆分新工艺
CN108947854B (zh) * 2018-06-30 2020-09-08 常州市阳光药业有限公司 重酒石酸间羟胺及其异构体的拆分方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1200886A (en) 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
JPH0285247A (ja) 1988-09-22 1990-03-26 Kohjin Co Ltd 光学活性チオウレア誘導体
US5399765A (en) 1994-05-23 1995-03-21 Sepracor, Inc. Enantioselective preparation of optically pure albuterol
US5545745A (en) 1994-05-23 1996-08-13 Sepracor, Inc. Enantioselective preparation of optically pure albuterol
AU2539399A (en) 1998-02-20 1999-09-06 Flaccida Investments (Proprietary) Limited Process for the production of optically enriched (r)- or (s)-albuterol
CN1173929C (zh) * 1999-10-19 2004-11-03 中国科学院成都有机化学研究所 光学纯肾上腺素类β-激动剂的组合拆分制备法
GB0030171D0 (en) 2000-12-11 2001-01-24 Cipla Ltd Process for preparing isomers of salbutamol

Also Published As

Publication number Publication date
CA2431400A1 (en) 2002-06-20
USRE43984E1 (en) 2013-02-05
US20040054215A1 (en) 2004-03-18
EP1349828B1 (de) 2005-03-16
HK1060345A1 (en) 2004-08-06
USRE43844E1 (en) 2012-12-04
DE60109494T2 (de) 2005-08-04
EP1349828A1 (de) 2003-10-08
CA2431400C (en) 2008-01-22
US6995286B2 (en) 2006-02-07
AU2002220918A1 (en) 2002-06-24
ES2240335T3 (es) 2005-10-16
PT1349828E (pt) 2005-07-29
ATE291006T1 (de) 2005-04-15
GB0030171D0 (en) 2001-01-24
WO2002048090A1 (en) 2002-06-20

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8365 Fully valid after opposition proceedings