DE69708950D1 - Verfahren zur Herstellung von 2'-Deoxy-2'-Halocoformycin oder Stereoisomere davon - Google Patents

Verfahren zur Herstellung von 2'-Deoxy-2'-Halocoformycin oder Stereoisomere davon

Info

Publication number
DE69708950D1
DE69708950D1 DE69708950T DE69708950T DE69708950D1 DE 69708950 D1 DE69708950 D1 DE 69708950D1 DE 69708950 T DE69708950 T DE 69708950T DE 69708950 T DE69708950 T DE 69708950T DE 69708950 D1 DE69708950 D1 DE 69708950D1
Authority
DE
Germany
Prior art keywords
deoxy
halocoformycin
chem
formula
epi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69708950T
Other languages
English (en)
Other versions
DE69708950T2 (de
Inventor
Tomio Takeuchi
Sumio Umezawa
Tsutomu Tsuchiya
Yoshiaki Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Application granted granted Critical
Publication of DE69708950D1 publication Critical patent/DE69708950D1/de
Publication of DE69708950T2 publication Critical patent/DE69708950T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69708950T 1996-03-07 1997-03-06 Verfahren zur Herstellung von 2'-Deoxy-2'-Halocoformycin oder Stereoisomere davon Expired - Fee Related DE69708950T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8078084A JPH09241294A (ja) 1996-03-07 1996-03-07 ２′−デオキシ−２′−ハロコホルマイシン又はその立体異性体の製造法

Publications (2)

Publication Number Publication Date
DE69708950D1 true DE69708950D1 (de) 2002-01-24
DE69708950T2 DE69708950T2 (de) 2002-08-08

Family

ID=13651989

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69708950T Expired - Fee Related DE69708950T2 (de) 1996-03-07 1997-03-06 Verfahren zur Herstellung von 2'-Deoxy-2'-Halocoformycin oder Stereoisomere davon

Country Status (6)

Country Link
US (1) US5831072A (de)
EP (1) EP0794194B1 (de)
JP (1) JPH09241294A (de)
AT (1) ATE210676T1 (de)
DE (1) DE69708950T2 (de)
ES (1) ES2168586T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE027338T2 (en) * 2003-09-15 2016-09-28 Hospira Uk Ltd Synthesis and preparation of pentostatin and its precursors, analogues and derivatives
FR2881798B1 (fr) 2005-02-10 2010-08-20 Valeo Equip Electr Moteur Dispositif de demarrage d'un moteur thermique
US20100261666A1 (en) * 2009-04-14 2010-10-14 The Board Of Trustees Of The University Of Illinois Compositions and methods for the treatment of myocardial dysfunction associated with sirs or sepsis
CN113980860B (zh) * 2021-11-23 2023-09-08 天津商业大学 一种高产喷司他丁和2’-氨基-2’-脱氧腺苷的野野村菌及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923785A (en) * 1974-04-22 1975-12-02 Parke Davis & Co (R)-3-(2-deoxy-{62 -D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo{8 4,5-d{9 {8 1,3{9 diazepin-8-ol
US4117229A (en) * 1977-10-11 1978-09-26 Warner-Lambert Company 2-amino-1-(5-amino-1h-imidazol-4-yl)ethanone and method of preparation
US4713372A (en) * 1984-03-16 1987-12-15 Warner-Lambert Company 2-chloropentostatin compound having adenosine diaminase inhibitory activity
ATE34176T1 (de) * 1984-03-16 1988-05-15 Warner Lambert Co 2'-chloropentostatin, eine diese verbindung enthaltende pharmazeutische zusammensetzung und ein mikroorganismus zur herstellung dieser verbindung.
JPS61199797A (ja) * 1985-02-28 1986-09-04 Kitasato Inst:The 新規化合物アデクロリンおよびその製造法
JPH0798832B2 (ja) * 1987-05-01 1995-10-25 財団法人微生物化学研究会 イミダゾジアゼピン誘導体
NO169858C (no) * 1989-03-02 1992-08-12 Roger Sten Snarli Innretning ved rulle- eller foldesjalusi
JP3030087B2 (ja) * 1991-11-14 2000-04-10 財団法人微生物化学研究会 ２´−デオキシ−２´−フルオロコホルマイシンとその立体異性体

Also Published As

Publication number Publication date
EP0794194B1 (de) 2001-12-12
DE69708950T2 (de) 2002-08-08
EP0794194A1 (de) 1997-09-10
ES2168586T3 (es) 2002-06-16
JPH09241294A (ja) 1997-09-16
US5831072A (en) 1998-11-03
ATE210676T1 (de) 2001-12-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee