ATE204173T1 - Verwendung von 1-beta-d-ribofuranosyl-1,2,4- triazol-3-carboxamid (ribavirin) zur herstellung eines medikaments für die behandlung von arboviren - Google Patents
Verwendung von 1-beta-d-ribofuranosyl-1,2,4- triazol-3-carboxamid (ribavirin) zur herstellung eines medikaments für die behandlung von arbovirenInfo
- Publication number
- ATE204173T1 ATE204173T1 AT94118300T AT94118300T ATE204173T1 AT E204173 T1 ATE204173 T1 AT E204173T1 AT 94118300 T AT94118300 T AT 94118300T AT 94118300 T AT94118300 T AT 94118300T AT E204173 T1 ATE204173 T1 AT E204173T1
- Authority
- AT
- Austria
- Prior art keywords
- ribofuranosyl
- carboxamide
- triazole
- arboviruses
- ribavirin
- Prior art date
Links
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 title 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229960000329 ribavirin Drugs 0.000 title 1
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 title 1
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 241000712891 Arenavirus Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241000713112 Orthobunyavirus Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66625284A | 1984-10-29 | 1984-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE204173T1 true ATE204173T1 (de) | 2001-09-15 |
Family
ID=24673430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94118300T ATE204173T1 (de) | 1984-10-29 | 1985-04-16 | Verwendung von 1-beta-d-ribofuranosyl-1,2,4- triazol-3-carboxamid (ribavirin) zur herstellung eines medikaments für die behandlung von arboviren |
Country Status (18)
| Country | Link |
|---|---|
| EP (3) | EP0383361A3 (de) |
| JP (1) | JPH0713019B2 (de) |
| KR (1) | KR860003018A (de) |
| AT (1) | ATE204173T1 (de) |
| AU (1) | AU584333B2 (de) |
| BE (1) | BE902199A (de) |
| CA (1) | CA1261265A (de) |
| DD (1) | DD261094A5 (de) |
| DE (3) | DE3588232T2 (de) |
| ES (1) | ES8704962A1 (de) |
| FR (1) | FR2572286B1 (de) |
| GB (1) | GB2166050B (de) |
| LU (1) | LU85854A1 (de) |
| NL (1) | NL300083I1 (de) |
| NZ (1) | NZ212510A (de) |
| PH (1) | PH22534A (de) |
| PT (1) | PT81387B (de) |
| ZA (1) | ZA858237B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE126696T1 (de) * | 1985-12-23 | 1995-09-15 | Hutchinson Fred Cancer Res | Regulierung der retroviralen replikation, infektion und pathogenese. |
| JP2792246B2 (ja) * | 1991-01-31 | 1998-09-03 | 信越半導体株式会社 | 単結晶棒クランプ位置決め治具及びこれを用いた単結晶棒クランプ位置決め方法 |
| PL364699A1 (en) * | 1999-01-29 | 2004-12-13 | Icn Pharmaceuticals, Inc. | Modulation of immune response by ribavirin |
| US6720000B2 (en) | 2001-03-19 | 2004-04-13 | Three Rivers Pharmaceutical, Llc | Process for producing wet ribavirin pellets |
| US7132453B2 (en) * | 2002-03-15 | 2006-11-07 | Vanderbilt University | Method of using prostacyclin to treat respiratory syncytial virus infections |
| US7538094B2 (en) | 2002-09-19 | 2009-05-26 | Three Rivers Pharmacueticals, Llc | Composition containing ribavirin and use thereof |
| US20170128482A1 (en) | 2014-06-23 | 2017-05-11 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Modified release pharmaceutical compositions of sofosbuvir and ribavirin |
| US20170151272A1 (en) | 2014-06-23 | 2017-06-01 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | A novel pharmaceutical composition of sofosbuvir and ribavirin |
| EA201692507A1 (ru) | 2014-06-23 | 2017-04-28 | Сановель Илач Санайи Ве Тиджарет А.Ш. | Фармацевтические комбинации софосбувира и рибавирина |
| JP2018076280A (ja) * | 2016-10-28 | 2018-05-17 | 国立大学法人 大分大学 | ジカウイルス感染症治療用医薬組成物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3798209A (en) * | 1971-06-01 | 1974-03-19 | Icn Pharmaceuticals | 1,2,4-triazole nucleosides |
| US3927216A (en) * | 1971-06-01 | 1975-12-16 | Icn Pharmaceuticals | 1,2,4-Triazol E-3-carboxamides for inhibiting virus infections |
| US4211771A (en) * | 1971-06-01 | 1980-07-08 | Robins Ronald K | Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide |
| AR205339A1 (es) * | 1973-03-12 | 1976-04-30 | Icn Pharmaceuticals | Sintesis de 1,2,4-triazolo-3-carboxamidas utiles como agentes antivirales |
| WO1983003383A1 (en) * | 1982-03-29 | 1983-10-13 | Liposome Co Inc | Stable plurilamellar vesicles |
-
1985
- 1985-04-15 BE BE0/214849A patent/BE902199A/fr not_active IP Right Cessation
- 1985-04-16 GB GB8509689A patent/GB2166050B/en not_active Expired
- 1985-04-16 DE DE3588232T patent/DE3588232T2/de not_active Expired - Lifetime
- 1985-04-16 DE DE198585302644T patent/DE181050T1/de active Pending
- 1985-04-16 AT AT94118300T patent/ATE204173T1/de active
- 1985-04-16 EP EP19900105678 patent/EP0383361A3/de not_active Withdrawn
- 1985-04-16 EP EP85302644A patent/EP0181050A3/de not_active Withdrawn
- 1985-04-16 EP EP94118300A patent/EP0643970B1/de not_active Revoked
- 1985-04-16 DE DE2002199005 patent/DE10299005I2/de active Active
- 1985-04-17 LU LU85854A patent/LU85854A1/fr unknown
- 1985-04-30 AU AU41807/85A patent/AU584333B2/en not_active Expired
- 1985-05-07 CA CA000480878A patent/CA1261265A/en not_active Expired
- 1985-05-16 PH PH32282A patent/PH22534A/en unknown
- 1985-05-30 FR FR858508143A patent/FR2572286B1/fr not_active Expired - Fee Related
- 1985-05-30 KR KR1019850003752A patent/KR860003018A/ko not_active Ceased
- 1985-06-05 JP JP60122351A patent/JPH0713019B2/ja not_active Expired - Fee Related
- 1985-06-21 NZ NZ212510A patent/NZ212510A/xx unknown
- 1985-10-09 DD DD85281565A patent/DD261094A5/de active Search and Examination
- 1985-10-28 ZA ZA858237A patent/ZA858237B/xx unknown
- 1985-10-28 PT PT81387A patent/PT81387B/pt active IP Right Revival
- 1985-10-29 ES ES548303A patent/ES8704962A1/es not_active Expired
-
2002
- 2002-02-14 NL NL300083C patent/NL300083I1/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES548303A0 (es) | 1987-04-16 |
| JPH0713019B2 (ja) | 1995-02-15 |
| ZA858237B (en) | 1988-02-24 |
| DE181050T1 (de) | 1986-12-18 |
| CA1261265A (en) | 1989-09-26 |
| HK1010985A1 (en) | 1999-07-02 |
| DE10299005I1 (de) | 2002-05-08 |
| LU85854A1 (fr) | 1985-12-16 |
| NL300083I1 (nl) | 2002-05-01 |
| DE3588232D1 (de) | 2001-09-20 |
| AU584333B2 (en) | 1989-05-25 |
| EP0643970B1 (de) | 2001-08-16 |
| EP0181050A3 (de) | 1987-10-21 |
| PT81387B (pt) | 1987-11-11 |
| DE10299005I2 (de) | 2004-07-01 |
| PT81387A (en) | 1985-11-01 |
| GB2166050A (en) | 1986-04-30 |
| FR2572286B1 (fr) | 1990-03-23 |
| EP0181050A2 (de) | 1986-05-14 |
| GB8509689D0 (en) | 1985-05-22 |
| AU4180785A (en) | 1986-05-08 |
| BE902199A (fr) | 1985-07-31 |
| PH22534A (en) | 1988-10-17 |
| JPS61109723A (ja) | 1986-05-28 |
| GB2166050B (en) | 1989-08-16 |
| EP0643970A3 (de) | 1997-07-09 |
| EP0643970A2 (de) | 1995-03-22 |
| NZ212510A (en) | 1989-04-26 |
| DE3588232T2 (de) | 2002-06-13 |
| FR2572286A1 (fr) | 1986-05-02 |
| EP0383361A3 (de) | 1993-06-16 |
| KR860003018A (ko) | 1986-05-19 |
| DD261094A5 (de) | 1988-10-19 |
| ES8704962A1 (es) | 1987-04-16 |
| EP0383361A2 (de) | 1990-08-22 |
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