DE69637518D1 - Homogene vervielfältigung und nachweis von nukleinsäuren - Google Patents
Homogene vervielfältigung und nachweis von nukleinsäurenInfo
- Publication number
- DE69637518D1 DE69637518D1 DE69637518T DE69637518T DE69637518D1 DE 69637518 D1 DE69637518 D1 DE 69637518D1 DE 69637518 T DE69637518 T DE 69637518T DE 69637518 T DE69637518 T DE 69637518T DE 69637518 D1 DE69637518 D1 DE 69637518D1
- Authority
- DE
- Germany
- Prior art keywords
- duplication
- homogenous
- detection
- nucleic acids
- nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000001514 detection method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US909095P | 1995-12-22 | 1995-12-22 | |
| PCT/US1996/019751 WO1997023647A1 (en) | 1995-12-22 | 1996-12-20 | Homogeneous amplification and detection of nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69637518D1 true DE69637518D1 (de) | 2008-06-19 |
Family
ID=21735499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69637518T Expired - Fee Related DE69637518D1 (de) | 1995-12-22 | 1996-12-20 | Homogene vervielfältigung und nachweis von nukleinsäuren |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5914230A (de) |
| EP (1) | EP0876510B1 (de) |
| JP (1) | JP2001517925A (de) |
| CA (1) | CA2239683A1 (de) |
| DE (1) | DE69637518D1 (de) |
| WO (1) | WO1997023647A1 (de) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1223831A (en) | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| US7195871B2 (en) * | 1996-01-24 | 2007-03-27 | Third Wave Technologies, Inc | Methods and compositions for detecting target sequences |
| US7256020B2 (en) * | 1996-11-29 | 2007-08-14 | Third Wave Technologies, Inc. | Methods and compositions for detecting target sequences |
| US7745142B2 (en) | 1997-09-15 | 2010-06-29 | Molecular Devices Corporation | Molecular modification assays |
| US6297018B1 (en) | 1998-04-17 | 2001-10-02 | Ljl Biosystems, Inc. | Methods and apparatus for detecting nucleic acid polymorphisms |
| WO1999023258A1 (en) * | 1997-10-31 | 1999-05-14 | Gen-Probe Incorporated | Methods of nucleic acid detection |
| EP1930078A1 (de) * | 1998-05-01 | 2008-06-11 | Gen-Probe Incorporated | Verfahren zum Umrühren des Inhalts eines Containers |
| ATE440963T1 (de) | 1998-07-02 | 2009-09-15 | Gen Probe Inc | Molekulare fackeln |
| AU3748800A (en) * | 1999-03-16 | 2000-10-04 | Ljl Biosystems, Inc. | Methods and apparatus for detecting nucleic acid polymorphisms |
| US6346384B1 (en) * | 2000-03-27 | 2002-02-12 | Dade Behring Inc. | Real-time monitoring of PCR using LOCI |
| ES2370232T3 (es) * | 2000-05-04 | 2011-12-13 | Siemens Healthcare Diagnostics Products Gmbh | Procedimiento para la detección de múltiples analitos. |
| DE10123183A1 (de) * | 2000-05-18 | 2001-11-22 | Becton Dickinson Co | Modifizierte Amplifikationsprimer und ihre Verwendung |
| US20030082549A1 (en) * | 2000-08-30 | 2003-05-01 | Xiangjun Liu | Method for determining alleles |
| CA2460759C (en) * | 2001-09-24 | 2011-05-31 | One Lambda | Diagnostic probe detection system |
| EP1546392A4 (de) | 2002-08-02 | 2006-05-24 | Stratatech Corp | Spezies-spezifischer dna-nachweis |
| US7851150B2 (en) | 2002-12-18 | 2010-12-14 | Third Wave Technologies, Inc. | Detection of small nucleic acids |
| US8206904B2 (en) * | 2002-12-18 | 2012-06-26 | Third Wave Technologies, Inc. | Detection of nucleic acids |
| WO2004057017A2 (en) | 2002-12-18 | 2004-07-08 | Third Wave Technologies, Inc. | Detection of small nucleic acids |
| US7297780B2 (en) | 2003-01-06 | 2007-11-20 | Third Wave Technologies, Inc. | Reactive functional groups for preparation of modified nucleic acid |
| JP4782668B2 (ja) | 2003-03-31 | 2011-09-28 | エフ．ホフマン−ラ ロシュ アーゲー | 日本脳炎ウィルス血清グループのメンバーを包含する一定のフラビウィルスを検出するための組成物及び方法 |
| WO2005012548A2 (en) * | 2003-08-01 | 2005-02-10 | Dynal Biotech Inc. | Self-hybridizing multiple target nucleic acid probes and methods of use |
| US20050118727A1 (en) * | 2003-12-01 | 2005-06-02 | Carsten Schelp | Conjugates and their use in detection methods |
| WO2005062048A1 (de) * | 2003-12-01 | 2005-07-07 | Dade Behring Marburg Gmbh | Homogenes nachweisverfahren |
| WO2005060618A2 (en) * | 2003-12-19 | 2005-07-07 | California Institute Of Technology | Enzyme-free isothermal exponential amplification of nucleic acids and nucleic acid analog signals |
| US7462451B2 (en) * | 2004-04-26 | 2008-12-09 | Third Wave Technologies, Inc. | Compositions for modifying nucleic acids |
| EP1778867B1 (de) | 2004-07-01 | 2010-04-28 | Gen-Probe Incorporated | Verfahren und zusammensetzungen zum nachweis von nukleinsäuren in einer biologischen probe |
| DE102005000021A1 (de) * | 2005-03-16 | 2006-09-21 | Köhler, Thomas, Dr. | Verfahren und Testkit zur Detektion von Ziel-Nukleinsäuren |
| US20070026423A1 (en) * | 2005-03-16 | 2007-02-01 | Thomas Koehler | Method and test kit for the detection of target nucleic acids |
| WO2007059348A2 (en) * | 2005-11-17 | 2007-05-24 | Third Wave Technologies, Inc. | Compositions and methods for detecting an hcv-1 subtype |
| CA2654016C (en) | 2006-06-01 | 2016-01-05 | Third Wave Technologies, Inc. | Detection of nucleic acids |
| KR20090078341A (ko) * | 2006-10-03 | 2009-07-17 | 고꾸리츠 다이가꾸호오징 기후다이가꾸 | Ｄｎａｊ 유전자를 사용한 박테리아의 검출, 및 그의 용도 |
| US8043810B2 (en) * | 2007-05-02 | 2011-10-25 | Eagle Eye Research, Inc. | Analyte detection using autocatalytic chain reactions |
| GB0713183D0 (en) * | 2007-07-06 | 2007-08-15 | King S College London | Method |
| WO2009033156A2 (en) * | 2007-09-07 | 2009-03-12 | Third Wave Technologies, Inc. | Methods and applications for target quantification |
| CA2718011C (en) * | 2008-03-15 | 2015-05-19 | Hologic, Inc. | Compositions and methods for analysis of nucleic acid molecules during amplification reaction using footprint probes |
| CA2723726C (en) | 2008-05-13 | 2017-09-12 | Michael M. Becker | Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences |
| JP2012509675A (ja) * | 2008-11-25 | 2012-04-26 | ジェン−プロウブ インコーポレイテッド | 低分子ｒｎａを検出するための組成物および方法、ならびにその使用 |
| US20110091931A1 (en) * | 2009-04-24 | 2011-04-21 | Colby Pharmaceutical Company | Methods and Kits for Determining Oxygen Free Radical (OFR) Levels in Animal and Human Tissues as a Prognostic Marker for Cancer and Other Pathophysiologies |
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| US9910040B2 (en) * | 2012-07-09 | 2018-03-06 | Sevident, Inc. | Molecular nets comprising capture agents and linking agents |
| WO2011084772A2 (en) | 2009-12-21 | 2011-07-14 | Northwestern University | Allelic disorders caused by mutations in trpv4 |
| DE102010003781B4 (de) * | 2010-04-08 | 2012-08-16 | Aj Innuscreen Gmbh | Verfahren zum Nachweis spezifischer Nukleinsäuresequenzen |
| CN103675303B (zh) | 2010-07-23 | 2016-02-03 | 贝克曼考尔特公司 | 传感器系统 |
| US20150225792A1 (en) | 2014-01-17 | 2015-08-13 | Northwestern University | Compositions and methods for identifying depressive disorders |
| US10233501B2 (en) | 2010-10-19 | 2019-03-19 | Northwestern University | Biomarkers predictive of predisposition to depression and response to treatment |
| US10093981B2 (en) | 2010-10-19 | 2018-10-09 | Northwestern University | Compositions and methods for identifying depressive disorders |
| US20150218639A1 (en) | 2014-01-17 | 2015-08-06 | Northwestern University | Biomarkers predictive of predisposition to depression and response to treatment |
| CA2826696C (en) | 2011-02-02 | 2019-12-03 | Exact Sciences Corporation | Digital sequence analysis of dna methylation |
| CN104450680A (zh) | 2011-05-12 | 2015-03-25 | 精密科学公司 | 核酸的分离 |
| US8993341B2 (en) | 2011-05-12 | 2015-03-31 | Exact Sciences Corporation | Removal of PCR inhibitors |
| US8808990B2 (en) | 2011-05-12 | 2014-08-19 | Exact Sciences Corporation | Serial isolation of multiple DNA targets from stool |
| EP2776844B1 (de) | 2011-11-07 | 2020-09-30 | Beckman Coulter, Inc. | Probenbehälterdetektion |
| JP2014532881A (ja) | 2011-11-07 | 2014-12-08 | ベックマン コールター， インコーポレイテッド | 標本輸送システムのための磁気制動 |
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| ES2778054T3 (es) | 2011-11-07 | 2020-08-07 | Beckman Coulter Inc | Sistema y método para transportar recipientes de muestras |
| US9482684B2 (en) | 2011-11-07 | 2016-11-01 | Beckman Coulter, Inc. | Centrifuge system and workflow |
| US9446418B2 (en) | 2011-11-07 | 2016-09-20 | Beckman Coulter, Inc. | Robotic arm |
| ES2645418T3 (es) | 2011-12-22 | 2017-12-05 | Ibis Biosciences, Inc. | Amplificación de una secuencia de un ácido ribonucleico |
| CN102559661B (zh) * | 2012-01-18 | 2014-06-04 | 厦门基科生物科技有限公司 | 一种新型连接酶反应介导的扩增方法及用途 |
| ES2905448T3 (es) | 2012-05-10 | 2022-04-08 | Massachusetts Gen Hospital | Métodos para determinar una secuencia nucleotídica |
| AU2013205064B2 (en) | 2012-06-04 | 2015-07-30 | Gen-Probe Incorporated | Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid |
| US9212392B2 (en) | 2012-09-25 | 2015-12-15 | Exact Sciences Corporation | Normalization of polymerase activity |
| CA2902916C (en) | 2013-03-14 | 2018-08-28 | Mayo Foundation For Medical Education And Research | Detecting neoplasm |
| AU2014321355B2 (en) | 2013-09-20 | 2019-10-10 | The Regents Of The University Of Michigan | Compositions and methods for the analysis of radiosensitivity |
| US10253358B2 (en) | 2013-11-04 | 2019-04-09 | Exact Sciences Development Company, Llc | Multiple-control calibrators for DNA quantitation |
| CN117106868A (zh) * | 2013-11-26 | 2023-11-24 | 杭州联川基因诊断技术有限公司 | 一种扩增靶核酸的试剂盒和方法 |
| US9909181B2 (en) | 2013-12-13 | 2018-03-06 | Northwestern University | Biomarkers for post-traumatic stress states |
| EP4209600A1 (de) | 2013-12-19 | 2023-07-12 | Exact Sciences Corporation | Synthetische nukleinsäurekontrollmoleküle |
| AU2015209079B2 (en) | 2014-01-27 | 2021-07-15 | Archerdx, Llc | Methods of preparing nucleic acids for sequencing |
| JP2017514467A (ja) * | 2014-04-23 | 2017-06-08 | チルドレンズ メディカル センター コーポレーション | 核酸キャリパーを用いた高スループット構造決定 |
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| US10683534B2 (en) | 2015-01-27 | 2020-06-16 | BioSpyder Technologies, Inc. | Ligation assays in liquid phase |
| EP3230476B1 (de) | 2014-12-12 | 2020-02-05 | Exact Sciences Development Company, LLC | Zdhhc1 zur normalisierung von methylierungsdetektionstests |
| CA3183545A1 (en) | 2014-12-12 | 2016-06-16 | Exact Sciences Corporation | Compositions and methods for performing methylation detection assays |
| US10435755B2 (en) | 2015-03-27 | 2019-10-08 | Exact Sciences Development Company, Llc | Detecting esophageal disorders |
| WO2017010854A1 (ko) * | 2015-07-13 | 2017-01-19 | 국립암센터 | 나노입자를 이용한 핵산 검출용 키트 및 핵산 검출 방법 |
| KR101817155B1 (ko) * | 2015-07-13 | 2018-01-11 | 국립암센터 | 나노입자를 이용한 핵산 검출용 키트 및 핵산 검출 방법 |
| US10040069B2 (en) | 2015-07-23 | 2018-08-07 | General Electric Company | Amplification and detection of nucleic acids |
| CN108350485A (zh) | 2015-10-30 | 2018-07-31 | 精密科学发展有限责任公司 | 血浆dna的多重扩增检测测定以及分离和检测 |
| EP3414327B1 (de) * | 2016-02-10 | 2020-09-30 | The Regents of The University of Michigan | Nachweis von nukleinsäuren |
| US10385406B2 (en) | 2016-05-05 | 2019-08-20 | Exact Sciences Development Company, Llc | Detection of lung neoplasia by analysis of methylated DNA |
| US20170321286A1 (en) | 2016-05-05 | 2017-11-09 | Exact Sciences Corporation | Detection of lung neoplasia by amplification of rna sequences |
| WO2018017710A1 (en) | 2016-07-19 | 2018-01-25 | Exact Sciences Development Company, Llc | Nucleic acid control molecules from non-human organisms |
| EP3488004B1 (de) | 2016-07-19 | 2021-10-06 | Exact Sciences Development Company, LLC | Methylierte kontroll-dna |
| ES2956257T3 (es) | 2016-09-02 | 2023-12-18 | Mayo Found Medical Education & Res | Detección de carcinoma hepatocelular |
| AU2017328950B2 (en) | 2016-09-15 | 2023-09-14 | Archerdx, Llc | Methods of nucleic acid sample preparation |
| EP3512965B1 (de) | 2016-09-15 | 2024-03-13 | ArcherDX, LLC | Verfahren zur herstellung von nukleinsäuren zur analyse von zellfreier dna |
| US10427162B2 (en) | 2016-12-21 | 2019-10-01 | Quandx Inc. | Systems and methods for molecular diagnostics |
| CN110475875B (zh) | 2017-01-27 | 2024-06-25 | 精密科学公司 | 通过分析甲基化dna检测结肠瘤形成 |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| JP7348603B2 (ja) | 2018-04-02 | 2023-09-21 | エニュメラ・モレキュラー・インコーポレイテッド | 核酸分子を計数するための方法、システム、および組成物 |
| US11408030B2 (en) | 2018-09-10 | 2022-08-09 | Andy Madrid | Test for detecting Alzheimer's disease |
| WO2020206170A1 (en) | 2019-04-02 | 2020-10-08 | Progenity, Inc. | Methods, systems, and compositions for counting nucleic acid molecules |
| KR20220092561A (ko) | 2019-10-31 | 2022-07-01 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 난소암 검출 |
| US20230357852A1 (en) | 2020-08-19 | 2023-11-09 | Mayo Foundation For Medical Education And Research | Detecting non-hodgkin lymphoma |
| EP4214243A1 (de) | 2020-09-21 | 2023-07-26 | Progenity, Inc. | Zusammensetzungen und verfahren zur isolierung von zellfreier dna |
| WO2023011660A1 (en) | 2021-08-06 | 2023-02-09 | Sansure Biotech Inc. | Compositions for liquefying a viscous biological sample, combination products, liquefying agents, and kits thereof, and methods and application thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU600900B2 (en) * | 1985-05-02 | 1990-08-30 | Genetics Institute Inc. | Process and nucleic acid construct for producing reagent complexes useful in determining target nucleotide sequences |
| US4868104A (en) * | 1985-09-06 | 1989-09-19 | Syntex (U.S.A.) Inc. | Homogeneous assay for specific polynucleotides |
| DE3785591T2 (de) * | 1986-01-10 | 1993-09-02 | Amoco Corp | Kompetitiver homogener test. |
| EP0259453A1 (de) * | 1986-03-04 | 1988-03-16 | Cambridge Biotech Corporation | Nachweis von nukleinsäure durch partikel-agglutination |
| WO1990002205A1 (en) * | 1988-08-25 | 1990-03-08 | Angenics, Inc. | Detection of nucleic acid sequences using particle agglutination |
| EP0557456A4 (en) * | 1990-11-14 | 1995-11-15 | Siska Diagnostics Inc | Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor |
| WO1992014845A1 (en) * | 1991-02-26 | 1992-09-03 | Worcester Foundation For Experimental Biology | Diagnosing cystic fibrosis and other genetic diseases using fluorescence resonance energy transfer (fret) |
| ES2146215T3 (es) * | 1991-11-15 | 2000-08-01 | Igen Int Inc | Ensayos rapidos para productos de amplificacion. |
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| JPH08505531A (ja) * | 1993-01-15 | 1996-06-18 | ザ パブリック ヘルス リサーチ インスティチュート オブ ザ シティー オブ ニューヨーク インク | Ｒｎａバイナリ・プローブとリボザイムリガーゼを用いたｒｎａ検定法 |
| DE4344742A1 (de) * | 1993-06-09 | 1994-12-15 | Boehringer Mannheim Gmbh | Verfahren zur Immobilisierung von Nukleinsäuren |
| US5624803A (en) * | 1993-10-14 | 1997-04-29 | The Regents Of The University Of California | In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom |
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| DE4436534A1 (de) * | 1994-10-13 | 1996-04-18 | Bayer Ag | Verfahren und Vorrichtung zur Beschichtung von Rotationskörpern mit nicht geradlinig verlaufender Achse |
| US5753439A (en) * | 1995-05-19 | 1998-05-19 | Trustees Of Boston University | Nucleic acid detection methods |
| EP0845047A2 (de) * | 1995-08-14 | 1998-06-03 | Abbott Laboratories | Eintopf-amplifikationstestverfahren für nukleinsäuren |
| US20030083758A1 (en) * | 2001-11-01 | 2003-05-01 | Williamson Charles G. | Remote updating of intelligent household appliances |
-
1996
- 1996-12-20 US US08/771,624 patent/US5914230A/en not_active Expired - Fee Related
- 1996-12-20 CA CA002239683A patent/CA2239683A1/en not_active Abandoned
- 1996-12-20 JP JP52370097A patent/JP2001517925A/ja not_active Ceased
- 1996-12-20 DE DE69637518T patent/DE69637518D1/de not_active Expired - Fee Related
- 1996-12-20 WO PCT/US1996/019751 patent/WO1997023647A1/en active Application Filing
- 1996-12-20 EP EP96945934A patent/EP0876510B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997023647A1 (en) | 1997-07-03 |
| US5914230A (en) | 1999-06-22 |
| JP2001517925A (ja) | 2001-10-09 |
| CA2239683A1 (en) | 1997-07-03 |
| EP0876510B1 (de) | 2008-05-07 |
| EP0876510A1 (de) | 1998-11-11 |
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