DE69635822D1 - Beobachtung von verbindungen mittels elektrochemilumineszenz - Google Patents
Beobachtung von verbindungen mittels elektrochemilumineszenzInfo
- Publication number
- DE69635822D1 DE69635822D1 DE69635822T DE69635822T DE69635822D1 DE 69635822 D1 DE69635822 D1 DE 69635822D1 DE 69635822 T DE69635822 T DE 69635822T DE 69635822 T DE69635822 T DE 69635822T DE 69635822 D1 DE69635822 D1 DE 69635822D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- electrochemiluminescence
- observation
- compound
- transformable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000000034 method Methods 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2415/00—Assays, e.g. immunoassays or enzyme assays, involving penicillins or cephalosporins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/30—Electrochemically active labels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/40—Rare earth chelates
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US485419 | 1990-02-27 | ||
| US08/485,419 US5643713A (en) | 1995-06-07 | 1995-06-07 | Electrochemiluminescent monitoring of compounds |
| PCT/US1996/009805 WO1996040978A1 (en) | 1995-06-07 | 1996-06-07 | Electrochemiluminescent monitoring of compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69635822D1 true DE69635822D1 (de) | 2006-04-20 |
| DE69635822T2 DE69635822T2 (de) | 2006-10-19 |
Family
ID=23928088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69635822T Expired - Fee Related DE69635822T2 (de) | 1995-06-07 | 1996-06-07 | Beobachtung von verbindungen mittels elektrochemilumineszenz |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5643713A (de) |
| EP (1) | EP0836651B1 (de) |
| JP (2) | JP3997436B2 (de) |
| AT (1) | ATE317913T1 (de) |
| CA (1) | CA2222926C (de) |
| DE (1) | DE69635822T2 (de) |
| ES (1) | ES2258777T3 (de) |
| WO (1) | WO1996040978A1 (de) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641623A (en) * | 1995-01-04 | 1997-06-24 | Martin; Mark T. | Electrochemiluminescence assay |
| US6316180B1 (en) * | 1995-01-04 | 2001-11-13 | Igen International, Inc. | Electrochemiluminescent monitoring of compounds/electrochemiluminescence assays |
| US20010003647A1 (en) * | 1995-06-07 | 2001-06-14 | Ji Sun | Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US6613583B1 (en) | 1997-06-27 | 2003-09-02 | Igen International, Inc. | Electrochemiluminescent label based on multimetallic assemblies |
| US6312896B1 (en) * | 1998-09-17 | 2001-11-06 | Igen Inaternational, Inc. | Assays for measuring nucleic acid binding proteins and enzyme activities |
| US7141436B2 (en) * | 1999-11-03 | 2006-11-28 | Science And Technology Corp. | Immunoassay and reagents and kits for performing the same |
| US6977722B2 (en) | 2001-06-29 | 2005-12-20 | Meso Scale Technologies, Llc. | Assay plates, reader systems and methods for luminescence test measurements |
| EP1412487B1 (de) | 2001-07-30 | 2010-06-16 | Meso Scale Technologies LLC | Assay-elektroden mit schichten aus immobilisiertem lipid/protein sowie verfahren zu deren herstellung und verwendung |
| US7858321B2 (en) | 2001-09-10 | 2010-12-28 | Meso Scale Technologies, Llc | Methods and apparatus for conducting multiple measurements on a sample |
| AU2003295495A1 (en) * | 2002-11-15 | 2004-06-15 | Applera Corporation | Nucleic acid sequence detection |
| CA2587945A1 (en) * | 2004-11-17 | 2007-04-12 | Bioveris | Electrochemiluminescent assay |
| US20060275841A1 (en) * | 2004-12-20 | 2006-12-07 | Martin Blankfard | Assay method and apparatus with reduced sample matrix effects |
| JP5205062B2 (ja) * | 2005-02-10 | 2013-06-05 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 酸化還元活性構造体およびそれを利用するデバイス |
| US20070116600A1 (en) * | 2005-06-23 | 2007-05-24 | Kochar Manish S | Detection device and methods associated therewith |
| DK2271938T3 (da) | 2008-04-11 | 2014-05-12 | Univ Texas | Fremgangsmåde og apparat til nanopartikel-elektrogenereret kemiluminescens-amplifikation |
| KR101603356B1 (ko) | 2008-05-08 | 2016-03-14 | 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 전기발생 화학발광에 사용되는 발광 나노구조 물질 |
| US20100261292A1 (en) | 2009-04-10 | 2010-10-14 | Meso Scale Technologies, Llc | Methods for Conducting Assays |
| CA3203856A1 (en) | 2009-07-27 | 2011-02-10 | Meso Scale Technologies, Llc | Assay apparatuses, consumables and methods |
| EP4300100A2 (de) | 2010-10-14 | 2024-01-03 | Meso Scale Technologies, LLC | Reagenzienlagerung in einer assay-vorrichtung |
| CN103443614B (zh) | 2010-10-25 | 2015-07-22 | 霍夫曼-拉罗奇有限公司 | 信号增强化合物在电化学发光检测中的用途 |
| EP3467500B1 (de) | 2011-11-11 | 2021-05-12 | Eli N. Glezer | Durch co-binder unterstützte testverfahren |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| US9081001B2 (en) | 2012-05-15 | 2015-07-14 | Wellstat Diagnostics, Llc | Diagnostic systems and instruments |
| JP6416785B2 (ja) | 2013-01-04 | 2018-10-31 | メソ スケール テクノロジーズ エルエルシー | マルチウェルプレートおよびコンタクトプラットフォームを利用した電気化学発光分析用計器 |
| CA3153763A1 (en) | 2013-03-11 | 2014-10-09 | Meso Scale Technologies, Llc. | Improved methods for conducting multiplexed assays |
| US10114015B2 (en) | 2013-03-13 | 2018-10-30 | Meso Scale Technologies, Llc. | Assay methods |
| WO2014165061A1 (en) | 2013-03-13 | 2014-10-09 | Meso Scale Technologies, Llc. | Improved assay methods |
| EP2970631B1 (de) | 2013-03-15 | 2017-05-03 | Lubrizol Advanced Materials, Inc. | Schwermetallfreie, chlorierte pvc zusammensetzungen |
| IL229525A0 (en) | 2013-11-20 | 2014-01-30 | Yeda Res & Dev | Metal complexes of tris-bipyridyl and their uses in electrochromic applications |
| CA2947747C (en) | 2014-05-09 | 2024-03-05 | Meso Scale Technologies, Llc. | Graphene-modified electrodes |
| CN112239774A (zh) | 2014-05-15 | 2021-01-19 | 中尺度技术有限责任公司 | 改进的测定方法 |
| ES2717535T3 (es) | 2014-12-08 | 2019-06-21 | Hoffmann La Roche | Procedimiento para la medición de vitamina D |
| EP3338094B1 (de) | 2015-08-20 | 2019-05-08 | H. Hoffnabb-La Roche Ag | Partikelbasierter immunoassay unter verwendung eines pegylierten analytspezifischen bindemittels |
| BR112018017336A2 (pt) | 2016-03-07 | 2018-12-26 | Hoffmann La Roche | método in vitro para detectar um anticorpo para p53 (anticorpo anti-p53) em uma amostra e polipeptídeo de fusão |
| JP7039481B2 (ja) | 2016-03-11 | 2022-03-22 | エフ．ホフマン－ラ ロシュ アーゲー | 電気化学発光検出における分枝鎖アミン |
| EP3577460B1 (de) | 2017-02-02 | 2021-01-20 | Roche Diagnostics GmbH | Immunoassay mit mindestens zwei pegylierten analyt-spezifischen bindungsmitteln |
| WO2019164180A1 (ko) * | 2018-02-21 | 2019-08-29 | 고려대학교 세종산학협력단 | 유기전계발광소자용 조성물, 이로부터 제조된 정공주입층 재료 및 정공주입층을 포함하는 유기전계발광소자 |
| US11686013B2 (en) | 2018-02-23 | 2023-06-27 | Meso Scale Technologies, Llc. | Methods of screening antigen-binding molecules by normalizing for the concentration of antigen-binding molecule |
| CN111936522A (zh) | 2018-04-18 | 2020-11-13 | 豪夫迈·罗氏有限公司 | 新型抗胸苷激酶抗体 |
| EP3844503A1 (de) | 2018-08-31 | 2021-07-07 | F. Hoffmann-La Roche AG | Thymidinkinase (tk-1) in prognostischen indizes für dlbcl |
| AU2019418498A1 (en) | 2019-01-03 | 2021-07-15 | Meso Scale Technologies, Llc | Compositions and methods for carrying out assay measurements |
| US20220099661A1 (en) | 2019-03-01 | 2022-03-31 | Meso Scale Technologies, Llc. | Electrochemiluminescent labeled probes for use in immunoassay methods, methods using such and kits comprising same |
| CN113939599A (zh) | 2019-06-07 | 2022-01-14 | 豪夫迈·罗氏有限公司 | 杂交全lna寡核苷酸 |
| JP2022542056A (ja) | 2019-07-22 | 2022-09-29 | エフ．ホフマン－ラ ロシュ アーゲー | 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ６ |
| CN114144674A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | P物质作为用于子宫内膜异位症的非侵入性诊断的血液生物标志物 |
| BR112022000172A2 (pt) | 2019-07-22 | 2022-02-22 | Hoffmann La Roche | Métodos para avaliar se uma paciente tem endometriose, para selecionar uma paciente para terapia e para monitorar uma paciente |
| BR112022001140A2 (pt) | 2019-07-22 | 2022-03-15 | Hoffmann La Roche | Métodos para avaliar se um paciente tem endometriose ou está em risco de desenvolver endometriose, selecionar um paciente para terapia e monitorar um paciente que sofre de endometriose ou que está sendo tratado para endometriose |
| CN114144673A (zh) | 2019-07-22 | 2022-03-04 | 豪夫迈·罗氏有限公司 | S100a8作为血液生物标志物用于子宫内膜异位症的非侵入性诊断 |
| BR112022009371A2 (pt) | 2019-11-15 | 2022-08-09 | Hoffmann La Roche | Métodos para determinar a quantidade ou concentração de um ou mais analitos antibióticos, tubos de amostragem, usos de um reagente de derivatização nucleofílica e analito antibiótico |
| US20240018571A1 (en) | 2020-05-19 | 2024-01-18 | Meso Scale Technologies, Llc. | Methods, compositions, and kits for nucleic acid detection |
| IL299495A (en) | 2020-07-01 | 2023-02-01 | Meso Scale Technologies Llc | Compositions and methods for making measurements |
| EP4200597A2 (de) | 2020-08-21 | 2023-06-28 | Meso Scale Technologies, LLC | Elektrochemische zellen mit hilfselektroden mit definiertem grenzflächenpotenzial und verfahren zur verwendung davon |
| JP2023547505A (ja) | 2020-11-02 | 2023-11-10 | エフ． ホフマン－ラ ロシュ アーゲー | ＳＡＲＳ－ＣｏＶ－２ヌクレオカプシド抗体 |
| WO2022136234A1 (en) | 2020-12-22 | 2022-06-30 | F. Hoffmann-La Roche Ag | Method for detecting an analyte of interest in a sample |
| WO2022207628A1 (en) | 2021-03-30 | 2022-10-06 | F. Hoffmann-La Roche Ag | Scf as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2022207685A1 (en) | 2021-04-01 | 2022-10-06 | F. Hoffmann-La Roche Ag | Psp94 as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2022243210A1 (en) | 2021-05-17 | 2022-11-24 | F. Hoffmann-La Roche Ag | sFRP4 AS BLOOD BIOMARKER FOR THE NON-INVASIVE DIAGNOSIS OF ADENOMYOSIS |
| AU2022325891A1 (en) | 2021-08-13 | 2024-03-14 | Meso Scale Technologies, Llc. | Electrochemical cell devices and methods of manufacturing |
| WO2023072904A1 (en) | 2021-10-26 | 2023-05-04 | F. Hoffmann-La Roche Ag | Monoclonal antibodies specific for sars-cov-2 rbd |
| WO2023129884A1 (en) | 2021-12-30 | 2023-07-06 | Meso Scale Technologies, Llc. | Methods for electrochemiluminescence detection |
| US20230213476A1 (en) | 2022-01-04 | 2023-07-06 | Meso Scale Technologies, Llc. | Electrochemical cell devices and methods of manufacturing |
| WO2023131594A1 (en) | 2022-01-05 | 2023-07-13 | F. Hoffmann-La Roche Ag | Derivatization of compounds in patient samples for therapeutic drug monitoring (tdm) |
| WO2023156510A1 (en) | 2022-02-18 | 2023-08-24 | F. Hoffmann-La Roche Ag | Method for detecting an analyte of interest in a sample |
| WO2023247752A1 (en) | 2022-06-23 | 2023-12-28 | F. Hoffmann-La Roche Ag | Method for diagnosing endometriosis and for classifying the stage of endometriosis |
| WO2024017983A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Meteorin-like protein (metrnl) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017982A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Leukotriene a4 hydrolase (lta4h) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
| WO2024017985A1 (en) | 2022-07-22 | 2024-01-25 | F. Hoffmann-La Roche Ag | Fibroblast growth factor binding protein 1 (fgfbp1) as (blood) biomarker for the diagnosis of polycystic ovarian syndrome |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3905871A (en) * | 1971-05-14 | 1975-09-16 | Syva Co | Lactam conjugates to enzymes |
| US4238195A (en) * | 1979-01-18 | 1980-12-09 | Miles Laboratories, Inc. | Fluorescer-labeled specific binding assays |
| US4372745A (en) * | 1979-12-19 | 1983-02-08 | Electro-Nucleonics, Inc. | Chemical luminescence amplification substrate system for immunochemistry involving microencapsulated fluorescer |
| EP0050965A1 (de) * | 1980-10-23 | 1982-05-05 | Takeda Chemical Industries, Ltd. | Beta-Lactamase inhibierende Zusammensetzung |
| US4396579A (en) * | 1981-08-06 | 1983-08-02 | Miles Laboratories, Inc. | Luminescence detection device |
| US4713328A (en) * | 1981-09-30 | 1987-12-15 | Yolken Robert H | Microbial Enzyme assays |
| JPS60200167A (ja) * | 1984-03-24 | 1985-10-09 | Toyobo Co Ltd | 化学発光法による過酸化水素の定量法 |
| US5310687A (en) * | 1984-10-31 | 1994-05-10 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US5221605A (en) * | 1984-10-31 | 1993-06-22 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US4764462A (en) * | 1985-08-23 | 1988-08-16 | Georgetown University | Detectably labeled cephalosporin assay for beta-lactamase |
| EP0261591B1 (de) * | 1986-09-22 | 1993-03-10 | Nippon Kayaku Kabushiki Kaisha | Verfahren zur Bestimmung von 1,5-Anhydroglucitol und Ausrüstung dafür |
| US5057302A (en) * | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
| JPH0630628B2 (ja) * | 1987-12-16 | 1994-04-27 | キング醸造株式会社 | 生細胞数及び活力の測定方法 |
| US5321143A (en) * | 1988-05-26 | 1994-06-14 | Massachusetts Institute Of Technology | Ruthenium-catalyzed production of cyclic sulfates |
| US5238610A (en) * | 1988-10-06 | 1993-08-24 | The United States Of America As Represented By The Secretary Of The Navy | Method of detecting oxidizing agents in aqueous media through the use of chemiluminescent microemulsions |
| US5264346A (en) * | 1991-06-03 | 1993-11-23 | Chen Kirk C S | Colorimetric method for beta-lactamase assay and its applications |
| US5321243A (en) * | 1992-02-18 | 1994-06-14 | International Verifact Inc. | Card reader apparatus with read head mounting structure and card guide |
-
1995
- 1995-06-07 US US08/485,419 patent/US5643713A/en not_active Expired - Lifetime
-
1996
- 1996-06-07 CA CA002222926A patent/CA2222926C/en not_active Expired - Fee Related
- 1996-06-07 EP EP96923255A patent/EP0836651B1/de not_active Expired - Lifetime
- 1996-06-07 ES ES96923255T patent/ES2258777T3/es not_active Expired - Lifetime
- 1996-06-07 DE DE69635822T patent/DE69635822T2/de not_active Expired - Fee Related
- 1996-06-07 AT AT96923255T patent/ATE317913T1/de not_active IP Right Cessation
- 1996-06-07 WO PCT/US1996/009805 patent/WO1996040978A1/en active IP Right Grant
- 1996-06-07 JP JP50202097A patent/JP3997436B2/ja not_active Expired - Fee Related
-
1997
- 1997-06-23 US US08/880,209 patent/US6165708A/en not_active Expired - Fee Related
-
2006
- 2006-12-13 JP JP2006335216A patent/JP2007176939A/ja not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP3997436B2 (ja) | 2007-10-24 |
| CA2222926A1 (en) | 1996-12-19 |
| JP2007176939A (ja) | 2007-07-12 |
| US5643713A (en) | 1997-07-01 |
| AU6381796A (en) | 1996-12-30 |
| EP0836651A4 (de) | 2004-07-14 |
| ATE317913T1 (de) | 2006-03-15 |
| DE69635822T2 (de) | 2006-10-19 |
| EP0836651B1 (de) | 2006-02-15 |
| CA2222926C (en) | 2008-09-16 |
| AU708865B2 (en) | 1999-08-12 |
| EP0836651A1 (de) | 1998-04-22 |
| ES2258777T3 (es) | 2006-09-01 |
| WO1996040978A1 (en) | 1996-12-19 |
| JPH11507533A (ja) | 1999-07-06 |
| US6165708A (en) | 2000-12-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69635822D1 (de) | Beobachtung von verbindungen mittels elektrochemilumineszenz | |
| EA199700219A1 (ru) | Мультиматричное мультиспецифическое электрохемилюминесцентное испытание | |
| ES2073006T3 (es) | Secuestrantes asociados a polimeros de cascada, sus complejos y conjugados, proceso para su obtencion y preparados farmaceuticos que los contienen. | |
| DE69836888D1 (de) | Verfahren für Fluoreszenzerkennungstest | |
| ATE199263T1 (de) | Für den chemilumineszenz-nachweis verwendbare aryl-n-alkylacridanthiocarboxylat-derivate | |
| NO964187D0 (no) | Fremgangsmåte for fremstilling av mykobakterier | |
| DE69942068D1 (de) | Erzeugen eines nichtlinearen modells und erzeugen tzung desselben | |
| ES2179355T3 (es) | Derivados de tiazol utilizados como inhibidores de proteina quinasa c. | |
| DE69401717D1 (de) | Verfahren zur Aktivierung von polyanionischen,fluoreszierenden Farbstoffen in schwach dielektrischen Medien mit quaternären Oniumverbindungen | |
| FI941512A0 (fi) | Laitteisto ja menetelmä työstökoneen toiminnallisen tehokkuuden määrittämiseksi | |
| DE69108733D1 (de) | Bisphosphonsäurederivate als antiarthritische mittel. | |
| ES2079386T3 (es) | Ensayos para beta-lactamasa que utilizan los sustratos capaces de precipitar un cromogeno. | |
| ES2185218T3 (es) | Un plasma sanguineo aplicable universalmente. | |
| DE69609993D1 (de) | Calixarene und ihre verwendung für das abtrennen von metallen | |
| DE68919597T2 (de) | Spektrofluorometrisches verfahren und für dieses verfahren wertvolle verbindungen. | |
| FR2344837A1 (fr) | Installation d'emission acoustique permettant la detection des defauts de soudage | |
| ATE178410T1 (de) | Verfahren zur hochempfindlichen dosierung von herztroponin - i | |
| DE69509875D1 (de) | Nipecotinsäurederivate als antithrombische verbindungen | |
| NO972346L (no) | Aminoguanidinkarboksylater for behandling av ikke-insulinavhengig diabetes millitus | |
| GR1000664B (el) | Παρασκευη ενωσεων αντι-υπερχοληστερολαιμικης τετραζολης και ενδιαμεσων αυτων. | |
| DE69403550D1 (de) | Vorrichtung zur Herstellung von gebohrten Nadelrohlingen | |
| ES2097056T3 (es) | Calixarenos que contienen fosforo. | |
| FI942217A0 (fi) | Foer ytbehandling avsedd aemnessammansaettning samt ett saett att skydda ytorna pao byggnadsmaterial mot icke-oenskade reaktioner orsakade av mikroorganismer | |
| DE3860525D1 (de) | Vorrichtung zur erschliessung von muelldeponiegasquellen und zur erkundung und sanierung von altlasten und verunreinigten boeden. | |
| ATE29722T1 (de) | Verfahren zur debrominierung von dibromopenicillansaeure und derivaten. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |