DE69635184T2 - Vielfachkapillarfluoreszenzsensoranordnung - Google Patents

Vielfachkapillarfluoreszenzsensoranordnung Download PDF

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Publication number
DE69635184T2
DE69635184T2 DE69635184T DE69635184T DE69635184T2 DE 69635184 T2 DE69635184 T2 DE 69635184T2 DE 69635184 T DE69635184 T DE 69635184T DE 69635184 T DE69635184 T DE 69635184T DE 69635184 T2 DE69635184 T2 DE 69635184T2
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DE
Germany
Prior art keywords
vielfachkapillarfluoreszenzsensoranordnung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69635184T
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English (en)
Other versions
DE69635184D1 (de
Inventor
Stephen L Pentoney Jr
David J Rakestraw
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
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Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of DE69635184D1 publication Critical patent/DE69635184D1/de
Publication of DE69635184T2 publication Critical patent/DE69635184T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
DE69635184T 1995-04-26 1996-04-26 Vielfachkapillarfluoreszenzsensoranordnung Expired - Lifetime DE69635184T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/429,406 US5675155A (en) 1995-04-26 1995-04-26 Multicapillary fluorescent detection system
PCT/US1996/005903 WO1996034278A1 (en) 1995-04-26 1996-04-26 A multicapillary fluorescent detection system

Publications (2)

Publication Number Publication Date
DE69635184D1 DE69635184D1 (de) 2005-10-20
DE69635184T2 true DE69635184T2 (de) 2006-06-14

Family

ID=23703102

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69635184T Expired - Lifetime DE69635184T2 (de) 1995-04-26 1996-04-26 Vielfachkapillarfluoreszenzsensoranordnung

Country Status (5)

Country Link
US (1) US5675155A (de)
EP (1) EP0823052B1 (de)
JP (2) JPH11505015A (de)
DE (1) DE69635184T2 (de)
WO (1) WO1996034278A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022204582A1 (de) 2022-05-11 2023-11-16 Robert Bosch Gesellschaft mit beschränkter Haftung Verfahren und Vorrichtung zur korrekten Zuordnung zumindest eines Filters zu vorgegebenem Licht, insbesondere für eine Anwendung in der Molekular- oder Medizindiagnostik

Families Citing this family (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6972183B1 (en) 1997-06-16 2005-12-06 Diversa Corporation Capillary array-based enzyme screening
US20020048809A1 (en) * 1997-06-16 2002-04-25 Lafferty William Micharl Capillary array-based sample screening
US20010041333A1 (en) * 1997-06-16 2001-11-15 Short Jay M. High throughput screening for a bioactivity or biomolecule
US6794127B1 (en) * 1997-06-16 2004-09-21 Diversa Corporation Capillary array-based sample screening
US20040241759A1 (en) * 1997-06-16 2004-12-02 Eileen Tozer High throughput screening of libraries
US20020015997A1 (en) * 1997-06-16 2002-02-07 Lafferty William Michael Capillary array-based sample screening
US20030077620A1 (en) * 1997-06-16 2003-04-24 Diversa Corporation, A Delaware Corporation High throughput screening for sequences of interest
US20050070005A1 (en) * 1997-06-16 2005-03-31 Martin Keller High throughput or capillary-based screening for a bioactivity or biomolecule
US20030013115A1 (en) * 1997-06-16 2003-01-16 Diversa Corporation, A Delaware Corporation Capillary array-based sample screening
US6100535A (en) * 1998-01-29 2000-08-08 The Regents Of The University Of California Rotary confocal scanner for detection of capillary arrays
DE19803753C1 (de) * 1998-01-30 1999-12-02 Max Planck Gesellschaft Vorrichtung und Verfahren zur Kapillarelektrophorese
FR2774472B1 (fr) * 1998-01-30 2000-04-21 Centre Nat Rech Scient Perfectionnements aux systemes d'electrophorese multicapillaire
US6369893B1 (en) 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6818437B1 (en) * 1998-05-16 2004-11-16 Applera Corporation Instrument for monitoring polymerase chain reaction of DNA
EP3093649B1 (de) * 1998-05-16 2019-05-08 Life Technologies Corporation Eine kombination einer reaktionsvorrichtung und eines optischen instruments zur überwachung von dns-polymerasekettenreaktionen
US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
DE19829981C2 (de) * 1998-07-04 2002-10-17 Zeiss Carl Jena Gmbh Verfahren und Anordnung zur konfokalen Mikroskopie
WO2000004349A1 (en) * 1998-07-14 2000-01-27 Lewis E Neil High-throughput infrared spectroscopy
US6483112B1 (en) 1998-07-14 2002-11-19 E. Neil Lewis High-throughput infrared spectroscopy
US6759662B1 (en) * 1998-07-28 2004-07-06 Ce Resources Pte. Ltd. Optical detection system
US6225635B1 (en) * 1998-08-07 2001-05-01 The Regents Of The University Of California System and method for optically locating microchannel positions
JP3613032B2 (ja) * 1998-10-26 2005-01-26 株式会社日立製作所 キャピラリーアレイ電気泳動装置
US6690464B1 (en) * 1999-02-19 2004-02-10 Spectral Dimensions, Inc. High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units
EP1177441A1 (de) * 1999-05-10 2002-02-06 Prolinx, Inc. Vorrichtung zur zelltrennung und verfahren zur anwendung
WO2000068671A2 (en) * 1999-05-12 2000-11-16 Aclara Biosciences, Inc. Multiplexed fluorescent detection in microfluidic devices
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US6696022B1 (en) 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
US6630063B1 (en) * 1999-10-06 2003-10-07 I. Reich Family Limited Partnership Uniform laser excitation and detection in capillary array electrophoresis system and method
US6547943B1 (en) * 2000-05-25 2003-04-15 Spectrumedix Llc Capillary system providing multiple analysis of sample from same body of liquid
CA2436098C (en) 2001-01-26 2014-04-01 Biocal Technology, Inc. Optical detection in a multi-channel bio-separation system
ATE522802T1 (de) * 2001-01-26 2011-09-15 Qiagen Sciences Llc Mehrkanalkassette für biotrennung
WO2002072892A1 (en) 2001-03-12 2002-09-19 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension
US6932940B2 (en) * 2001-06-22 2005-08-23 Biocal Technology, Inc. Optical detection in bio-separation device using axial radiation input
CA2453390A1 (en) * 2001-07-25 2003-02-06 Applera Corporation Time-delay integration in electrophoretic detection systems
US6995841B2 (en) * 2001-08-28 2006-02-07 Rice University Pulsed-multiline excitation for color-blind fluorescence detection
US6870165B2 (en) 2001-10-19 2005-03-22 Biocal Technology, Inc. Multi-color multiplexed analysis in a bio-separation system
US20030162204A1 (en) * 2001-12-04 2003-08-28 Dave Smith Alcohol detection assembly
US7208072B2 (en) * 2002-01-18 2007-04-24 Biocal Technology, Inc. Multi-segment cartridge for bio-separation with multiplexed fluorescence detection
KR100483706B1 (ko) * 2002-04-04 2005-04-18 바디텍메드 주식회사 레이저 유발 표면형광 검출 장치
AU2002363822A1 (en) * 2002-11-20 2004-06-15 Richard Fritz Sauter Method for analyzing molecules for molecule sequencing and spectrometer therefor
US6967338B1 (en) * 2002-11-25 2005-11-22 The United States Of America As Represented By The Secretary Of The Army Micro UV particle detector
WO2004059312A1 (en) * 2002-12-20 2004-07-15 Corning Incorporated Capillary assay device and method
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US7981604B2 (en) 2004-02-19 2011-07-19 California Institute Of Technology Methods and kits for analyzing polynucleotide sequences
JP4224640B2 (ja) * 2004-03-29 2009-02-18 オリンパス株式会社 蛍光分光分析装置
US7635562B2 (en) 2004-05-25 2009-12-22 Helicos Biosciences Corporation Methods and devices for nucleic acid sequence determination
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
US7262859B2 (en) * 2004-10-13 2007-08-28 U.S. Genomics, Inc. Systems and methods for measurement optimization
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
FR2887626B1 (fr) * 2005-06-23 2008-02-15 Univ Nantes Etablissement Publ Capteur de spectrometre, dont les moyens optiques sont mobiles, et spectrometre correspondant
JP2007046904A (ja) 2005-08-05 2007-02-22 Sanyo Electric Co Ltd 反応検出装置
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
US20090305248A1 (en) * 2005-12-15 2009-12-10 Lander Eric G Methods for increasing accuracy of nucleic acid sequencing
CN101415813B (zh) 2006-02-03 2013-04-10 微芯片生物工艺学股份有限公司 微流体装置
WO2007091230A1 (en) * 2006-02-07 2007-08-16 Stokes Bio Limited A microfluidic analysis system
US7397546B2 (en) 2006-03-08 2008-07-08 Helicos Biosciences Corporation Systems and methods for reducing detected intensity non-uniformity in a laser beam
WO2008085991A2 (en) 2007-01-08 2008-07-17 U.S. Genomics, Inc. Reaction chamber
US7738094B2 (en) * 2007-01-26 2010-06-15 Becton, Dickinson And Company Method, system, and compositions for cell counting and analysis
US7518727B2 (en) * 2007-02-28 2009-04-14 Beckman Coulter, Inc. Multicapillary multilaser detection system
JP4525725B2 (ja) * 2007-10-18 2010-08-18 ソニー株式会社 光学測定部、光学測定用部材、及びこれらを配設した微小粒子測定装置、並びに微小粒子の光学測定方法
US20090253181A1 (en) 2008-01-22 2009-10-08 Microchip Biotechnologies, Inc. Universal sample preparation system and use in an integrated analysis system
US8361716B2 (en) 2008-10-03 2013-01-29 Pathogenetix, Inc. Focusing chamber
CN102803147B (zh) 2009-06-05 2015-11-25 尹特根埃克斯有限公司 通用样品准备系统以及在一体化分析系统中的用途
WO2012024658A2 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Integrated analysis system
US9121827B2 (en) 2011-06-30 2015-09-01 Mocon, Inc. Method of contemporaneously monitoring changes in analyte concentration in a plurality of samples on individual schedules
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
BR112014010718B1 (pt) 2011-11-16 2020-12-22 Becton, Dickinson And Company métodos, sistemas, dispositivos e kits para detecção de analito em amostra
JP2013160672A (ja) 2012-02-07 2013-08-19 Sony Corp 蛍光検出用光学系及び微小粒子分析装置
US8685708B2 (en) 2012-04-18 2014-04-01 Pathogenetix, Inc. Device for preparing a sample
US9028776B2 (en) 2012-04-18 2015-05-12 Toxic Report Llc Device for stretching a polymer in a fluid sample
CA2874870C (en) 2012-07-16 2020-07-07 Sharath Chandra MAHAVADI Capillary electrophoresis for reservoir fluid analysis at wellsite and laboratory
US20140065628A1 (en) * 2012-08-28 2014-03-06 Integenx Inc. Methods and Devices for Multi-Color, Out-of-Phase Detection in Electrophoresis
EP2929308A4 (de) 2012-12-05 2015-12-16 Genepoc Inc Optische abfragevorrichtung
US9678065B2 (en) 2013-01-11 2017-06-13 Becton, Dickinson And Company Low-cost point-of-care assay device
US10018590B2 (en) * 2013-08-15 2018-07-10 Schlumberger Technology Corporation Capillary electrophoresis for subterranean applications
US9797899B2 (en) 2013-11-06 2017-10-24 Becton, Dickinson And Company Microfluidic devices, and methods of making and using the same
CN105899936B (zh) 2013-11-13 2019-12-24 贝克顿·迪金森公司 光学成像系统及使用其的方法
CN110560187B (zh) 2013-11-18 2022-01-11 尹特根埃克斯有限公司 用于样本分析的卡盒和仪器
US10208332B2 (en) 2014-05-21 2019-02-19 Integenx Inc. Fluidic cartridge with valve mechanism
BR122020024355B1 (pt) 2014-10-14 2023-03-14 Becton, Dickinson And Company Dispositivo de mistura e transferência de espécime adaptado para receber uma amostra
AU2015334044B2 (en) 2014-10-14 2018-02-15 Becton, Dickinson And Company Blood sample management using open cell foam
EP3209410A4 (de) 2014-10-22 2018-05-02 IntegenX Inc. Systeme und verfahren zur automatisierten vorbereitung, verarbeitung und analyse von proben
AU2016229837B2 (en) 2015-03-10 2018-05-24 Becton, Dickinson And Company Biological fluid micro-sample management device
EP3311135B1 (de) 2015-06-17 2023-11-01 Becton, Dickinson and Company Streukappenanordnung für optischen detektor mit abnehmbarem streubalken und verfahren zur verwendung davon
US10151682B2 (en) * 2015-07-14 2018-12-11 Teilch Llc Airborne particle measuring device
EP3782730B1 (de) 2015-09-01 2024-01-10 Becton, Dickinson and Company Tiefenfiltervorrichtung zur trennung von probenphasen
US11085039B2 (en) 2016-12-12 2021-08-10 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
CA3046827A1 (en) 2016-12-12 2018-06-21 xCella Biosciences, Inc. Methods and systems for screening using microcapillary arrays
AU2017388058B2 (en) 2016-12-30 2023-02-02 xCella Biosciences, Inc. Multi-stage sample recovery system
US11346762B2 (en) 2018-01-23 2022-05-31 Becton, Dickinson And Company Systems for dynamic light detection obscuration and methods for using thereof
KR102133633B1 (ko) 2018-04-17 2020-07-13 (주)로고스바이오시스템스 핵산증폭반응산물을 실시간으로 검출하는 장치
CN109813692A (zh) * 2019-01-02 2019-05-28 北京科技大学 一种基于超声聚集的毛细管分析检测方法
CN113791059A (zh) * 2021-09-16 2021-12-14 大连理工大学 一种低背景信号的毛细管荧光仪

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2155176B (en) * 1984-01-16 1988-05-11 California Inst Of Techn Sequencing dna
US5246866A (en) * 1987-12-23 1993-09-21 Hitachi Software Engineering Co., Ltd. Method for transcription of a DNA sequence
US5274240A (en) * 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
US5091652A (en) * 1990-01-12 1992-02-25 The Regents Of The University Of California Laser excited confocal microscope fluorescence scanner and method
JP2873884B2 (ja) * 1991-03-22 1999-03-24 日立ソフトウェアエンジニアリング 株式会社 多色泳動パターン読み取り装置
DE69221423T2 (de) * 1991-09-30 1998-03-19 Beckman Instruments Inc Verbesserte Fluoreszenz-Erfassung von Proben in einem Kapillarrohr
WO1993019205A1 (en) * 1992-03-19 1993-09-30 The Regents Of The University Of California Multiple tag labeling method for dna sequencing
JP2815506B2 (ja) * 1992-04-14 1998-10-27 株式会社日立製作所 光検出型電気泳動装置
JPH09500443A (ja) * 1992-08-10 1997-01-14 バイオメトリック イメージング インコーポレイテッド 示差分離検定方法および試験キット
US5418371A (en) * 1993-02-01 1995-05-23 Aslund; Nils R. D. Apparatus for quantitative imaging of multiple fluorophores using dual detectors
US5371016A (en) * 1993-04-26 1994-12-06 Becton, Dickinson And Company Detecting biological activities in culture vials

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022204582A1 (de) 2022-05-11 2023-11-16 Robert Bosch Gesellschaft mit beschränkter Haftung Verfahren und Vorrichtung zur korrekten Zuordnung zumindest eines Filters zu vorgegebenem Licht, insbesondere für eine Anwendung in der Molekular- oder Medizindiagnostik

Also Published As

Publication number Publication date
EP0823052B1 (de) 2005-09-14
JP3626956B2 (ja) 2005-03-09
WO1996034278A1 (en) 1996-10-31
JP2003329590A (ja) 2003-11-19
DE69635184D1 (de) 2005-10-20
US5675155A (en) 1997-10-07
JPH11505015A (ja) 1999-05-11
EP0823052A1 (de) 1998-02-11

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Owner name: BECKMAN COULTER, INC., BREA, CALIF., US