DE69634142D1 - Neuartige affinitatsliganden und ihre verwendung - Google Patents
Neuartige affinitatsliganden und ihre verwendungInfo
- Publication number
- DE69634142D1 DE69634142D1 DE69634142T DE69634142T DE69634142D1 DE 69634142 D1 DE69634142 D1 DE 69634142D1 DE 69634142 T DE69634142 T DE 69634142T DE 69634142 T DE69634142 T DE 69634142T DE 69634142 D1 DE69634142 D1 DE 69634142D1
- Authority
- DE
- Germany
- Prior art keywords
- silicones
- novel affinity
- affinity
- novel
- affinity silicones
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
- B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3204—Inorganic carriers, supports or substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3253—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure not containing any of the heteroatoms nitrogen, oxygen or sulfur, e.g. aromatic structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3289—Coatings involving more than one layer of same or different nature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/48—Two nitrogen atoms
- C07D251/50—Two nitrogen atoms with a halogen atom attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/58—Use in a single column
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9519197 | 1995-09-20 | ||
GBGB9519197.9A GB9519197D0 (en) | 1995-09-20 | 1995-09-20 | Novel affinity ligands and their use |
PCT/DK1996/000399 WO1997010887A1 (en) | 1995-09-20 | 1996-09-19 | Novel affinity ligands and their use |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69634142D1 true DE69634142D1 (de) | 2005-02-03 |
DE69634142T2 DE69634142T2 (de) | 2005-12-29 |
Family
ID=10780990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69634142T Expired - Lifetime DE69634142T2 (de) | 1995-09-20 | 1996-09-19 | Neuartige affinitatsliganden und ihre verwendung |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0959975B1 (de) |
JP (1) | JP4824147B2 (de) |
KR (1) | KR100537386B1 (de) |
CN (1) | CN1089617C (de) |
AR (1) | AR003634A1 (de) |
AT (1) | ATE285827T1 (de) |
AU (1) | AU702901B2 (de) |
CA (1) | CA2232626C (de) |
DE (1) | DE69634142T2 (de) |
DK (1) | DK0959975T3 (de) |
ES (1) | ES2236748T3 (de) |
GB (1) | GB9519197D0 (de) |
MY (1) | MY127957A (de) |
RU (1) | RU2175261C2 (de) |
WO (1) | WO1997010887A1 (de) |
ZA (1) | ZA967917B (de) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5760187A (en) * | 1996-02-22 | 1998-06-02 | Mitsui Toatsu Chemicals, Inc. | Purification process of a human growth hormone |
AU729039C (en) | 1996-08-30 | 2001-08-02 | Upfront Chromatography A/S | Isolation of immunoglobulins |
EP0945447A1 (de) * | 1998-03-27 | 1999-09-29 | Janssen Pharmaceutica N.V. | Trisubstituierte 1,3,5-Triazinderivate zur Behandlung von HIV Infektionen |
GB9910807D0 (en) * | 1999-05-10 | 1999-07-07 | Prometic Biosciences Limited | Novel detoxification agents and their use |
EA005423B1 (ru) | 1999-09-24 | 2005-02-24 | Янссен Фармацевтика Н.В. | Противовирусные композиции |
US6153364A (en) * | 1999-12-16 | 2000-11-28 | Eastman Kodak Company | Photographic processing methods using compositions containing stain reducing agent |
US6153365A (en) | 1999-12-16 | 2000-11-28 | Eastman Kodak Company | Photographic processing compositions containing stain reducing agent |
AU2001259293A1 (en) | 2000-04-28 | 2001-11-12 | Accurate Polymers, Inc. | Simulated activity of protein a displayed by ligands attached to a cellulose bead surface |
US6440651B1 (en) | 2000-10-05 | 2002-08-27 | Eastman Kodak Company | Concentrated photographic fixer additive and fixing compositions and method of photographic processing |
US6288227B1 (en) | 2000-10-05 | 2001-09-11 | Eastman Kodak Company | Solublized 2,6-dinaphthylaminotriazines |
US6943162B2 (en) | 2001-01-26 | 2005-09-13 | Smithkline Beecham Corporation | Piperazinyltriazines as estrogen receptor modulators |
US7173032B2 (en) * | 2001-09-21 | 2007-02-06 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
GB0224446D0 (en) * | 2002-10-21 | 2002-11-27 | Univ Cambridge Tech | Affinity adsorbents for immunoglobulins |
GB0228724D0 (en) * | 2002-12-09 | 2003-01-15 | Prometic Biosciences Ltd | Multidimensinal libraries |
US7109040B2 (en) | 2002-12-13 | 2006-09-19 | Agilent Technologies, Inc. | Modular isotope coding approach to proteomic analysis |
US7700743B2 (en) | 2003-07-22 | 2010-04-20 | Millipore Corporation | Immobilised affinity medium and its use in separation |
SE0400501D0 (sv) * | 2004-02-27 | 2004-02-27 | Amersham Biosciences Ab | Antibody purification |
CA2552639C (en) | 2004-02-27 | 2012-05-01 | Ge Healthcare Bio-Sciences Ab | A process for the purification of antibodies |
SE0401665D0 (sv) * | 2004-06-24 | 2004-06-24 | Amersham Biosciences Ab | Purification of immunoglobulins |
GB0416699D0 (en) | 2004-07-27 | 2004-09-01 | Prometic Biosciences Ltd | Prion protein ligands and methods of use |
AU2005279615A1 (en) * | 2004-09-03 | 2006-03-09 | Prometic Biosciences Inc. | 2,4,6-triamino-s-triazine-based compounds which bind to the tail (Fc) portion of immunoglobulins and their use |
JP4831436B2 (ja) * | 2004-10-21 | 2011-12-07 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | クロマトグラフィーリガンド |
EP2360171A1 (de) | 2004-12-23 | 2011-08-24 | Novo Nordisk Health Care AG | Reduktion des Gehaltes an kontaminierenden Proteinen in Zusammensetzungen, die Vitamin K-abhängige Proteine von Interesse umfassen |
GB0509443D0 (en) * | 2005-05-09 | 2005-06-15 | Prometic Biosciences Ltd | Affinity adsorbents for factor VIII and von willebrand's factor |
GB0509438D0 (en) * | 2005-05-09 | 2005-06-15 | Prometic Biosciences Ltd | Affinity adsorbets for fibrinogen |
GB0509442D0 (en) * | 2005-05-09 | 2005-06-15 | Prometic Biosciences Ltd | Affinity adsorbents for fibrinogen |
US8501939B2 (en) | 2005-06-10 | 2013-08-06 | Prometic Biosciences Limited | Triazines and pyrimidines as protein binding ligands |
US20080220968A1 (en) * | 2005-07-05 | 2008-09-11 | Ge Healthcare Bio-Sciences Ab | [1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg |
GB0604236D0 (en) * | 2006-03-02 | 2006-04-12 | Prometic Biosciences Ltd | Adsorbents for protein purification |
JP5888481B2 (ja) | 2007-03-28 | 2016-03-22 | ディーピーエックス ホールディングス ビー.ブイ. | 膨張床カラムおよび使い捨て可能なクロマトグラフィー |
WO2008131547A1 (en) | 2007-04-30 | 2008-11-06 | Prometic Biosciences Inc. | 'triazine derivatives, compositions containing such derivatives, and methods of treatment of cancer and autoimmune diseases using such derivatives' |
GB0808908D0 (en) * | 2008-05-16 | 2008-06-25 | Avecia Biolog Ltd | Purification process |
US9273077B2 (en) | 2008-05-21 | 2016-03-01 | Ariad Pharmaceuticals, Inc. | Phosphorus derivatives as kinase inhibitors |
CA2723961C (en) | 2008-05-21 | 2017-03-21 | Ariad Pharmaceuticals, Inc. | Phosphorous derivatives as kinase inhibitors |
CN102216325A (zh) * | 2008-11-13 | 2011-10-12 | 诺沃-诺迪斯克有限公司 | 使用包括特异性配体的亲和树脂用于纯化人生长激素多肽的方法 |
US20100297243A1 (en) | 2009-04-15 | 2010-11-25 | Desai Neil P | Prion free nanoparticle compositions and methods of making thereof |
WO2010128142A1 (en) | 2009-05-07 | 2010-11-11 | Novozymes Biopharma Dk A/S | Method for purifying albumin |
EP2440548A1 (de) | 2009-06-10 | 2012-04-18 | Abbott Laboratories | 2- ( lh-pyrazol-4 -ylamin) -pyrimidin als kinasehemmer |
CA2769040A1 (en) * | 2009-07-28 | 2011-02-03 | Instraction Gmbh | Specific sorbent for binding proteins and peptides, and separation method using the same |
US8952150B2 (en) | 2009-09-23 | 2015-02-10 | Albert Einstein College Of Medicine Of Yeshiva University | Prostaglandin transporter inhibitors and uses thereof |
US9273151B2 (en) | 2011-03-24 | 2016-03-01 | Kaneka Corporation | Proteinaceous-substance-binding low-molecular-weight compound |
CN103501612B (zh) | 2011-05-04 | 2017-03-29 | 阿里亚德医药股份有限公司 | 抑制表皮生长因子受体导致的癌症中细胞增殖的化合物 |
WO2013169401A1 (en) | 2012-05-05 | 2013-11-14 | Ariad Pharmaceuticals, Inc. | Compounds for inhibiting cell proliferation in egfr-driven cancers |
US9611283B1 (en) | 2013-04-10 | 2017-04-04 | Ariad Pharmaceuticals, Inc. | Methods for inhibiting cell proliferation in ALK-driven cancers |
GB2513405A (en) * | 2013-04-26 | 2014-10-29 | Adc Biotechnology Ltd | Method of synthesising ADCs using affinity resins |
CN104148018B (zh) * | 2013-05-14 | 2018-04-20 | 上海亨臻实业有限公司 | 抗体亲和纯化材料及其用途 |
EP2918641A1 (de) | 2014-03-13 | 2015-09-16 | Basf Se | Reinigungsverfahren für Antikörper, Antikörperfragmente oder manipulierte Varianten davon mit spezifischen Anthrachinon-Farbstoffligandenstrukturen |
GB201419184D0 (en) | 2014-10-28 | 2014-12-10 | Adc Biotechnology Ltd | Method of synthesising biomolecule-effector/reporter-conjugates using affinity resins |
GB201419185D0 (en) | 2014-10-28 | 2014-12-10 | Adc Biotechnology Ltd | Method of synthesising ADCs using affinity resin |
RU2627849C1 (ru) * | 2016-07-22 | 2017-08-14 | Игорь Анатольевич Мнушкин | Способ разделения газового потока на отдельные компоненты или фракции |
RU2626354C9 (ru) * | 2016-07-25 | 2017-10-04 | Игорь Анатольевич Мнушкин | Способ разделения газового потока на отдельные компоненты или фракции |
CN109354600B (zh) * | 2018-11-29 | 2021-08-10 | 浙江海洋大学 | 一种牛磺酸修饰的新型阿拉斯加鳕鱼多功能肽的制备方法 |
CN113527284A (zh) * | 2021-07-16 | 2021-10-22 | 东莞市顶盛环保科技有限公司 | 一种含双酯基均三嗪衍生物的环保多功能材料及其制备方法与应用 |
CN113563324A (zh) * | 2021-07-22 | 2021-10-29 | 东莞市顶盛环保科技有限公司 | 一种含酯基均三嗪的绿色环保多功能材料及其制备方法与应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3726019A1 (de) * | 1987-08-05 | 1989-02-16 | Boehringer Mannheim Gmbh | Verfahren zur abtrennung und reinigung von t-pa |
-
1995
- 1995-09-20 GB GBGB9519197.9A patent/GB9519197D0/en active Pending
-
1996
- 1996-09-18 MY MYPI96003852A patent/MY127957A/en unknown
- 1996-09-19 AU AU69242/96A patent/AU702901B2/en not_active Expired
- 1996-09-19 DE DE69634142T patent/DE69634142T2/de not_active Expired - Lifetime
- 1996-09-19 DK DK96930037T patent/DK0959975T3/da active
- 1996-09-19 JP JP51233597A patent/JP4824147B2/ja not_active Expired - Lifetime
- 1996-09-19 WO PCT/DK1996/000399 patent/WO1997010887A1/en not_active Application Discontinuation
- 1996-09-19 RU RU98107896/12A patent/RU2175261C2/ru not_active IP Right Cessation
- 1996-09-19 CN CN96197849A patent/CN1089617C/zh not_active Expired - Lifetime
- 1996-09-19 ES ES96930037T patent/ES2236748T3/es not_active Expired - Lifetime
- 1996-09-19 ZA ZA967917A patent/ZA967917B/xx unknown
- 1996-09-19 EP EP96930037A patent/EP0959975B1/de not_active Expired - Lifetime
- 1996-09-19 AT AT96930037T patent/ATE285827T1/de active
- 1996-09-19 CA CA2232626A patent/CA2232626C/en not_active Expired - Lifetime
- 1996-09-19 KR KR1019980702097A patent/KR100537386B1/ko not_active IP Right Cessation
- 1996-09-20 AR ARP960104427A patent/AR003634A1/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2232626A1 (en) | 1997-03-27 |
KR19990063645A (ko) | 1999-07-26 |
WO1997010887A1 (en) | 1997-03-27 |
JPH11512442A (ja) | 1999-10-26 |
RU2175261C2 (ru) | 2001-10-27 |
ES2236748T3 (es) | 2005-07-16 |
CA2232626C (en) | 2011-11-29 |
DE69634142T2 (de) | 2005-12-29 |
ATE285827T1 (de) | 2005-01-15 |
MY127957A (en) | 2007-01-31 |
AU702901B2 (en) | 1999-03-11 |
EP0959975A1 (de) | 1999-12-01 |
DK0959975T3 (da) | 2005-05-09 |
JP4824147B2 (ja) | 2011-11-30 |
AU6924296A (en) | 1997-04-09 |
ZA967917B (en) | 1997-03-20 |
EP0959975B1 (de) | 2004-12-29 |
KR100537386B1 (ko) | 2006-04-21 |
CN1200680A (zh) | 1998-12-02 |
CN1089617C (zh) | 2002-08-28 |
AR003634A1 (es) | 1998-08-05 |
GB9519197D0 (en) | 1995-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69634142D1 (de) | Neuartige affinitatsliganden und ihre verwendung | |
DE69637691D1 (de) | Azeotropähnliche zusammensetzungen und ihre verwendung | |
DE69638056D1 (de) | Azeotropähnliche zusammensetzungen und ihre verwendung | |
DE69602787D1 (de) | Rotationsbremse und ihre Verwendung | |
DE69534880D1 (de) | MHC-Komplexe und ihre Verwendung | |
DE69413636D1 (de) | Reibungsmodifizierende Zusammensetzungen und ihre Verwendung | |
DE69617019D1 (de) | Fluorinierte alkenyltriazine und ihre verwendung als vernetzungsmittel | |
DE69532671D1 (de) | Endoprothesen und stents | |
DE69627188T2 (de) | Brille und brillenfassung | |
DE69513307T4 (de) | Zusammensetzung und verwendung | |
DE69820397D1 (de) | Ätzmittel und ihre Verwendung | |
DE69620270D1 (de) | Backfett und dessen Verwendung | |
DE59709806D1 (de) | Cycloolefincopolymere, ihre verwendung und daraus hergestellte formkörper | |
DE69628195D1 (de) | Verwendung von xyloglucanendotransglycosylase | |
DE69806419D1 (de) | Harzzusammensetzung und ihre Verwendung | |
DE69620914D1 (de) | Perfluoralkoxycycloalkancarbonylfluorid-zusammensetzungen und ihre verwendung | |
DE69615714T2 (de) | Phosphat-zusammensetzung und ihre verwendung | |
DE59708683D1 (de) | Kupfer-Chrom-Titan-Silizium-Legierung und ihre Verwendung | |
DE59610382D1 (de) | Halogenbenzimidazole und ihre verwendung als mikrobizide | |
DE69732095D1 (de) | Ionomerzusammensetzung und ihre verwendung | |
DE59607383D1 (de) | Farbstoffmischungen und ihre Verwendung | |
DE69328467T2 (de) | Polyamidzusammensetzung und Verwendung | |
DE69614491T2 (de) | 5HT1Dalpha und 5HT2A Ligande | |
DE69504049D1 (de) | Neue progesteronverbindung und ihre verwendung | |
DE69602782D1 (de) | Klebstoffzusammensetzung und ihre Verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |