DE69633094D1 - Heparansulfat 2-0-Sulfotransferase - Google Patents

Heparansulfat 2-0-Sulfotransferase

Info

Publication number
DE69633094D1
DE69633094D1 DE69633094T DE69633094T DE69633094D1 DE 69633094 D1 DE69633094 D1 DE 69633094D1 DE 69633094 T DE69633094 T DE 69633094T DE 69633094 T DE69633094 T DE 69633094T DE 69633094 D1 DE69633094 D1 DE 69633094D1
Authority
DE
Germany
Prior art keywords
sulfotransferase
heparan sulfate
heparan
sulfate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69633094T
Other languages
English (en)
Other versions
DE69633094T2 (de
Inventor
Masashi Kobayashi
Hiroko Habuchi
Osami Habuchi
Koji Kimata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Application granted granted Critical
Publication of DE69633094D1 publication Critical patent/DE69633094D1/de
Publication of DE69633094T2 publication Critical patent/DE69633094T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/13—Transferases (2.) transferring sulfur containing groups (2.8)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69633094T 1995-07-24 1996-07-23 Heparansulfat 2-0-Sulfotransferase Expired - Lifetime DE69633094T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18757795 1995-07-24
JP18757795A JP3672359B2 (ja) 1995-07-24 1995-07-24 ヘパラン硫酸 ２−ｏ−硫酸基転移酵素

Publications (2)

Publication Number Publication Date
DE69633094D1 true DE69633094D1 (de) 2004-09-16
DE69633094T2 DE69633094T2 (de) 2005-07-28

Family

ID=16208541

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69633094T Expired - Lifetime DE69633094T2 (de) 1995-07-24 1996-07-23 Heparansulfat 2-0-Sulfotransferase

Country Status (4)

Country Link
US (1) US5817487A (de)
EP (1) EP0756004B1 (de)
JP (1) JP3672359B2 (de)
DE (1) DE69633094T2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3672359B2 (ja) * 1995-07-24 2005-07-20 生化学工業株式会社 ヘパラン硫酸 ２−ｏ−硫酸基転移酵素
US6066318A (en) * 1995-10-05 2000-05-23 G.D. Searle & Co. Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors
US5773274A (en) * 1997-01-23 1998-06-30 Takara Shuzo., Ltd. Gene encoding sulfotransferase
JP4768936B2 (ja) * 2000-08-07 2011-09-07 生化学工業株式会社 硫酸基を有するオリゴ糖
DE602004024195D1 (de) * 2003-05-19 2009-12-31 Seikagaku Kogyo Co Ltd Sulfatgruppen-transferase-hemmer
WO2006124801A2 (en) 2005-05-12 2006-11-23 The University Of North Carolina At Chapel Hill Enzymatic synthesis of sulfated polysaccharides
WO2009014715A2 (en) * 2007-07-23 2009-01-29 The University Of North Carolina At Chapel Hill Enzymatic synthesis of sulfated polysaccharides without iduronic acid residues
ES2910476T3 (es) 2010-12-23 2022-05-12 Univ North Carolina Chapel Hill Síntesis quimioenzimática de heparinas de peso molecular ultra bajo estructuralmente homogéneas
ES2924830T3 (es) 2013-06-17 2022-10-11 Univ North Carolina Chapel Hill Moléculas de heparina reversibles
JP7330893B2 (ja) 2017-03-10 2023-08-22 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 短時間作用型ヘパリンベースの抗凝集剤化合物及び方法
WO2019010216A1 (en) 2017-07-03 2019-01-10 The University Of North Carolina At Chapel Hill ENZYMATIC SYNTHESIS OF HOMOGENEOUS CHONDROITIN SULFATE OLIGOSACCHARIDES
WO2019090203A1 (en) 2017-11-03 2019-05-09 The University Of North Carolina At Chapel Hill Sulfated oligosaccharides having anti-inflammatory activity
US11633424B2 (en) 2018-06-20 2023-04-25 The University Of North Carolina At Chapel Hill Cell protective methods and compositions
MX2021008479A (es) 2019-01-15 2021-10-13 Optimvia Llc Enzimas dependientes de aril sulfato modificadas por ingenieria genetica.
CA3144968A1 (en) 2019-07-09 2021-01-14 Optimvia Llc Methods for synthesizing anticoagulant polysaccharides
EP4182452A1 (de) 2020-07-14 2023-05-24 Optimvia, LLC Verfahren zur synthese von nicht-antikoagulierendem heparansulfat

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3818676B2 (ja) * 1994-07-22 2006-09-06 生化学工業株式会社 ヘパラン硫酸６−ｏ−硫酸基転移酵素
JP3672359B2 (ja) * 1995-07-24 2005-07-20 生化学工業株式会社 ヘパラン硫酸 ２−ｏ−硫酸基転移酵素

Also Published As

Publication number Publication date
DE69633094T2 (de) 2005-07-28
US5817487A (en) 1998-10-06
JPH0928374A (ja) 1997-02-04
EP0756004A1 (de) 1997-01-29
JP3672359B2 (ja) 2005-07-20
EP0756004B1 (de) 2004-08-11

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Legal Events

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