DE69505315T2 - Heparan sulfat 6-0-Sulfotransferase - Google Patents

Heparan sulfat 6-0-Sulfotransferase

Info

Publication number
DE69505315T2
DE69505315T2 DE69505315T DE69505315T DE69505315T2 DE 69505315 T2 DE69505315 T2 DE 69505315T2 DE 69505315 T DE69505315 T DE 69505315T DE 69505315 T DE69505315 T DE 69505315T DE 69505315 T2 DE69505315 T2 DE 69505315T2
Authority
DE
Germany
Prior art keywords
sulfotransferase
heparan sulfate
heparan
sulfate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69505315T
Other languages
English (en)
Other versions
DE69505315D1 (de
Inventor
Hiroko Habuchi
Osami Habuchi
Koji Kimata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Application granted granted Critical
Publication of DE69505315D1 publication Critical patent/DE69505315D1/de
Publication of DE69505315T2 publication Critical patent/DE69505315T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/13—Transferases (2.) transferring sulfur containing groups (2.8)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69505315T 1994-07-22 1995-07-20 Heparan sulfat 6-0-Sulfotransferase Expired - Lifetime DE69505315T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP17137994A JP3818676B2 (ja) 1994-07-22 1994-07-22 ヘパラン硫酸６−ｏ−硫酸基転移酵素

Publications (2)

Publication Number Publication Date
DE69505315D1 DE69505315D1 (de) 1998-11-19
DE69505315T2 true DE69505315T2 (de) 1999-05-20

Family

ID=15922091

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69505315T Expired - Lifetime DE69505315T2 (de) 1994-07-22 1995-07-20 Heparan sulfat 6-0-Sulfotransferase

Country Status (5)

Country Link
US (1) US5834282A (de)
EP (1) EP0693553B1 (de)
JP (1) JP3818676B2 (de)
CA (1) CA2154325C (de)
DE (1) DE69505315T2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3672359B2 (ja) * 1995-07-24 2005-07-20 生化学工業株式会社 ヘパラン硫酸 ２−ｏ−硫酸基転移酵素
JP4023848B2 (ja) * 1996-03-29 2007-12-19 生化学工業株式会社 硫酸化ラクトサミンオリゴ糖の製造方法
US5773274A (en) * 1997-01-23 1998-06-30 Takara Shuzo., Ltd. Gene encoding sulfotransferase
JP4768936B2 (ja) * 2000-08-07 2011-09-07 生化学工業株式会社 硫酸基を有するオリゴ糖
CA2441984A1 (en) * 2001-03-28 2002-10-10 Massachusetts Institute Of Technology Methods of 6-o-sulfating polysaccharides and 6-o-sulfated polysaccharide preparations
US20030114416A1 (en) * 2001-08-14 2003-06-19 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation with a cyclooxygenase-2 selective inhibitor and chondroitin sulfate
US20050101563A1 (en) * 2001-08-14 2005-05-12 Pharmacia Corporation Method and compositions for the treatment and prevention of pain and inflammation
DE602004024195D1 (de) 2003-05-19 2009-12-31 Seikagaku Kogyo Co Ltd Sulfatgruppen-transferase-hemmer
EP1885865A4 (de) 2005-05-12 2010-12-22 Univ North Carolina Enzymatische synthese sulfatierter polysaccharide
US20090035787A1 (en) * 2007-07-23 2009-02-05 The University Of North Carolina At Chapel Hill Enzymatic synthesis of sulfated polysaccharides without iduronic acid residues
WO2012088416A2 (en) 2010-12-23 2012-06-28 The University Of North Carolina At Chapel Hill Chemoenzymatic synthesis of structurally homogeneous ultra-low molecular weight heparins
WO2014165769A1 (en) * 2013-04-05 2014-10-09 Mo Bio Laboratories, Inc. Kits and methods for isolating protein from biological and environmental samples
EP3011043B1 (de) 2013-06-17 2022-05-11 The University of North Carolina At Chapel Hill Umkehrbare heparinmoleküle
WO2017040992A1 (en) 2015-09-04 2017-03-09 Mo Bio Laboratories, Inc. Methods for co-isolation of nucelic acids and proteins
CN110446511B (zh) 2017-03-10 2024-04-02 北卡罗来纳大学查珀尔希尔分校 短效的基于肝素的抗凝血剂化合物和方法
CN111601603A (zh) 2017-11-03 2020-08-28 北卡罗来纳大学查珀尔希尔分校 具有抗炎活性的硫酸化寡糖
EP3810152A4 (de) 2018-06-20 2022-04-27 The University of North Carolina at Chapel Hill Zellschutzverfahren und zusammensetzungen
EP3911737A1 (de) 2019-01-15 2021-11-24 Optimvia, LLC Gentechnisch hergestellte arylsulfat-abhängige enzyme
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
MX2022000343A (es) 2019-07-09 2022-03-11 Optimvia Llc Metodos para sintetizar polisacaridos anticoagulantes.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541095A (en) * 1992-06-16 1996-07-30 University Of Massachusetts Medical Center Glycosaminoglycan specific sulfotransferases

Also Published As

Publication number Publication date
US5834282A (en) 1998-11-10
CA2154325A1 (en) 1996-01-23
JPH0833483A (ja) 1996-02-06
CA2154325C (en) 2007-08-21
EP0693553A1 (de) 1996-01-24
JP3818676B2 (ja) 2006-09-06
DE69505315D1 (de) 1998-11-19
EP0693553B1 (de) 1998-10-14

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Legal Events

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