DE69631253T2 - Mobilisierung von haematopoietischen stammzellen durch ein chemokin - Google Patents
Mobilisierung von haematopoietischen stammzellen durch ein chemokin Download PDFInfo
- Publication number
- DE69631253T2 DE69631253T2 DE1996631253 DE69631253T DE69631253T2 DE 69631253 T2 DE69631253 T2 DE 69631253T2 DE 1996631253 DE1996631253 DE 1996631253 DE 69631253 T DE69631253 T DE 69631253T DE 69631253 T2 DE69631253 T2 DE 69631253T2
- Authority
- DE
- Germany
- Prior art keywords
- cells
- mobilization
- stem cells
- blood
- csf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US605195P | 1995-10-24 | 1995-10-24 | |
| US6051P | 1995-10-24 | ||
| PCT/US1996/016959 WO1997015594A1 (en) | 1995-10-24 | 1996-10-23 | Novel chemokine for mobilizing stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69631253D1 DE69631253D1 (de) | 2004-02-05 |
| DE69631253T2 true DE69631253T2 (de) | 2004-11-18 |
Family
ID=21719050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE1996631253 Expired - Fee Related DE69631253T2 (de) | 1995-10-24 | 1996-10-23 | Mobilisierung von haematopoietischen stammzellen durch ein chemokin |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0871664B1 (enExample) |
| JP (1) | JP2001519757A (enExample) |
| AU (1) | AU7468896A (enExample) |
| CA (1) | CA2235360A1 (enExample) |
| DE (1) | DE69631253T2 (enExample) |
| DK (1) | DK0871664T3 (enExample) |
| WO (1) | WO1997015594A1 (enExample) |
| ZA (1) | ZA968897B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451562B1 (en) | 1993-12-22 | 2002-09-17 | Human Genome Sciences, Inc. | Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides |
| US6488925B2 (en) | 1993-12-22 | 2002-12-03 | Human Genome Sciences, Inc. | Macrophage inflammatory protein-4 (MIP-4) polypeptides |
| US6811773B1 (en) | 1993-12-22 | 2004-11-02 | Human Genome Sciences, Inc. | Human monocyte colony inhibitory factor (M-CIF) polypeptides |
| US6001606A (en) * | 1994-03-08 | 1999-12-14 | Human Genome Sciences, Inc. | Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby |
| US6495129B1 (en) | 1994-03-08 | 2002-12-17 | Human Genome Sciences, Inc. | Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3) |
| US6075124A (en) * | 1994-05-16 | 2000-06-13 | Human Genome Sciences, Inc. | Human chemotactin protein |
| US5866373A (en) * | 1995-04-21 | 1999-02-02 | Human Genome Sciences, Inc. | Polynucleotide encoding a human chemotactic protein |
| US6100389A (en) | 1995-04-21 | 2000-08-08 | Human Genome Sciences, Inc. | Polynucleotides encoding a human chemotactic protein |
| US6174995B1 (en) | 1994-08-23 | 2001-01-16 | Haodong Li | Human chemokines, CKβ4 and CKβ10/MCP-4 |
| US6458349B1 (en) | 1995-06-02 | 2002-10-01 | Human Genome Sciences, Inc. | Chemokine β-4 polypeptides |
| US6391589B1 (en) | 1994-08-23 | 2002-05-21 | Human Genome Sciences, Inc. | Human chemokine beta-10 mutant polypeptides |
| US5981230A (en) * | 1994-08-23 | 1999-11-09 | Human Genome Sciences, Inc. | Polynucleotide encoding chemokine β-4 |
| US6139832A (en) * | 1995-02-08 | 2000-10-31 | Human Genome Sciences, Inc. | Leukocyte adhesion inhibitor-1 (LAI-1) Polypeptides |
| EP0859842A4 (en) * | 1995-09-29 | 1999-02-24 | Smithkline Beecham Corp | SHORT FORMS OF CHEMOKIN-g (b) -8 |
| US6290948B1 (en) * | 1996-05-14 | 2001-09-18 | Smithkline Beecham Corporation | Method of treating sepsis and ARDS using chamohine beta-10 |
| JP2001500382A (ja) * | 1996-09-30 | 2001-01-16 | ヒューマン ジノーム サイエンシーズ，インコーポレイテッド | 骨髄前駆体阻害因子―１（ｍｐｉｆ―１）、単球コロニー阻害因子（ｍ―ｃｉｆ）、およびマクロファージ阻害因子―４（ｍｉｐ―４）で疾患状態を処置するための治療組成物および方法 |
| US5912327A (en) * | 1996-09-30 | 1999-06-15 | Human Genome Sciences, Inc. | Method of purifying chemokines from inclusion bodies |
| EP0950066A1 (en) * | 1996-10-04 | 1999-10-20 | Human Genome Sciences, Inc. | THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING DISEASE STATES WITH LEUKOCYTE ADHESION INHIBITOR-1 (LAI-1), AND CHEMOKINE BETA-11 (Ck$g(b)-11) |
| JP2001506492A (ja) * | 1996-12-05 | 2001-05-22 | ヒューマン ゲノム サイエンシズ インク． | ヒトケモカインβ−１３ |
| AU5410698A (en) * | 1996-12-13 | 1998-07-03 | Shionogi & Co., Ltd. | Human cc chemokine elc |
| US6632425B1 (en) | 1997-03-20 | 2003-10-14 | Human Genome Sciences, Inc. | Chemokine compositions |
| US6028169A (en) * | 1997-03-31 | 2000-02-22 | Human Genome Sciences, Inc. | Chemokine β-6 antagonists |
| US6562800B1 (en) * | 1998-10-30 | 2003-05-13 | University Of Southern California | Use of immunopotentiating sequences for inducing immune response |
| JP2002529090A (ja) | 1998-11-10 | 2002-09-10 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ケモカインβ−７ |
| CA2359853A1 (en) * | 1999-01-08 | 2000-07-13 | Human Genome Sciences, Inc. | Human chemokine beta-10 mutant polypeptides |
| AU2505601A (en) * | 1999-11-15 | 2001-05-30 | Wolf-Georg Forssmann | Novel use of hcc-2 |
| AU2003225237A1 (en) | 2002-05-01 | 2003-11-17 | Human Genome Sciences, Inc. | Antibodies that specifically bind to chemokine beta-4 |
| CN103874707B (zh) | 2010-11-19 | 2017-04-19 | 卫材R&D管理有限公司 | 中和抗‑ccl20抗体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR970700438A (ko) * | 1993-12-22 | 1997-02-12 | 로버트 에이치. 벤슨 | 마크로파지 염증성 단백질-3,-4 및 -1감마(MACROPHAGE INFLAMMATORY PROTEINS -3,-4 AND -1sg(g)) |
| DE59410132D1 (de) * | 1993-12-24 | 2002-07-11 | Forssmann Wolf Georg | Humanes zirkulierendes cytokin cc-1 |
-
1996
- 1996-10-23 DK DK96936873T patent/DK0871664T3/da active
- 1996-10-23 AU AU74688/96A patent/AU7468896A/en not_active Abandoned
- 1996-10-23 JP JP51673897A patent/JP2001519757A/ja not_active Withdrawn
- 1996-10-23 DE DE1996631253 patent/DE69631253T2/de not_active Expired - Fee Related
- 1996-10-23 ZA ZA968897A patent/ZA968897B/xx unknown
- 1996-10-23 CA CA002235360A patent/CA2235360A1/en not_active Abandoned
- 1996-10-23 EP EP96936873A patent/EP0871664B1/en not_active Expired - Lifetime
- 1996-10-23 WO PCT/US1996/016959 patent/WO1997015594A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001519757A (ja) | 2001-10-23 |
| EP0871664A1 (en) | 1998-10-21 |
| CA2235360A1 (en) | 1997-05-01 |
| AU7468896A (en) | 1997-05-15 |
| ZA968897B (en) | 1998-07-14 |
| DE69631253D1 (de) | 2004-02-05 |
| WO1997015594A1 (en) | 1997-05-01 |
| DK0871664T3 (da) | 2004-04-26 |
| EP0871664A4 (en) | 2000-07-05 |
| EP0871664B1 (en) | 2004-01-02 |
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