DE69629300D1 - Triazol enthaltende antifungale mittel - Google Patents

Triazol enthaltende antifungale mittel

Info

Publication number
DE69629300D1
DE69629300D1 DE69629300T DE69629300T DE69629300D1 DE 69629300 D1 DE69629300 D1 DE 69629300D1 DE 69629300 T DE69629300 T DE 69629300T DE 69629300 T DE69629300 T DE 69629300T DE 69629300 D1 DE69629300 D1 DE 69629300D1
Authority
DE
Germany
Prior art keywords
triazolic
antifungal agents
antifungal
agents
triazolic antifungal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69629300T
Other languages
English (en)
Other versions
DE69629300T2 (de
Inventor
Simon Bell
Jonathan Fray
Patrick Marchington
Kenneth Richardson
Thomas Stephenson
John Whittle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ireland Pharmaceuticals
Original Assignee
Pfizer Research and Development Co NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Research and Development Co NV SA filed Critical Pfizer Research and Development Co NV SA
Publication of DE69629300D1 publication Critical patent/DE69629300D1/de
Application granted granted Critical
Publication of DE69629300T2 publication Critical patent/DE69629300T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
DE69629300T 1995-06-26 1996-06-05 Triazol enthaltende antifungale mittel Expired - Fee Related DE69629300T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9512961 1995-06-26
GBGB9512961.5A GB9512961D0 (en) 1995-06-26 1995-06-26 Antifungal agents
PCT/EP1996/002470 WO1997001552A1 (en) 1995-06-26 1996-06-05 Triazole antifungal agents

Publications (2)

Publication Number Publication Date
DE69629300D1 true DE69629300D1 (de) 2003-09-04
DE69629300T2 DE69629300T2 (de) 2004-03-04

Family

ID=10776672

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69629300T Expired - Fee Related DE69629300T2 (de) 1995-06-26 1996-06-05 Triazol enthaltende antifungale mittel

Country Status (25)

Country Link
US (1) US6015825A (de)
EP (1) EP0835252B1 (de)
JP (1) JP3105926B2 (de)
KR (1) KR19990028390A (de)
AR (1) AR002761A1 (de)
AT (1) ATE246186T1 (de)
AU (1) AU697405B2 (de)
BR (1) BR9609298A (de)
CA (1) CA2224983C (de)
CO (1) CO4480719A1 (de)
CZ (1) CZ415597A3 (de)
DE (1) DE69629300T2 (de)
DK (1) DK0835252T3 (de)
ES (1) ES2202453T3 (de)
GB (1) GB9512961D0 (de)
HU (1) HUP9803022A2 (de)
IL (1) IL118698A0 (de)
NO (1) NO976047L (de)
NZ (1) NZ311651A (de)
PE (1) PE4698A1 (de)
PL (1) PL324336A1 (de)
PT (1) PT835252E (de)
TR (1) TR199701699T1 (de)
WO (1) WO1997001552A1 (de)
ZA (1) ZA965365B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9602080D0 (en) * 1996-02-02 1996-04-03 Pfizer Ltd Pharmaceutical compounds
GB9713149D0 (en) 1997-06-21 1997-08-27 Pfizer Ltd Pharmaceutical formulations
US6645990B2 (en) 2000-08-15 2003-11-11 Amgen Inc. Thiazolyl urea compounds and methods of uses
KR100572996B1 (ko) * 2003-08-12 2006-04-25 한국화학연구원 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법
CA2548374C (en) 2003-12-23 2014-05-27 Astex Therapeutics Limited Pyrazole derivatives as protein kinase modulators
EP1902032A1 (de) 2005-06-22 2008-03-26 Astex Therapeutics Limited Pharmazeutische verbindungen
US8541461B2 (en) 2005-06-23 2013-09-24 Astex Therapeutics Limited Pharmaceutical combinations comprising pyrazole derivatives as protein kinase modulators
KR100738228B1 (ko) * 2006-02-22 2007-07-12 한국화학연구원 아졸계 항균제 화합물 및 그의 제조방법
GB0704932D0 (en) 2007-03-14 2007-04-25 Astex Therapeutics Ltd Pharmaceutical compounds
JP5266430B2 (ja) * 2010-04-24 2013-08-21 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
JP5953308B2 (ja) 2010-10-22 2016-07-20 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 殺害虫剤としての新規ヘテロ環式化合物
AU2011362281A1 (en) 2011-03-15 2013-09-05 Council Of Scientific & Industrial Research Enantiomers of fluconazole analogues containing thieno-[2,3-d]pyrimidin-4 (3H)-one moiety as antifungal agents
CN103764646A (zh) * 2011-06-19 2014-04-30 威尔金制药有限公司 金属酶抑制剂化合物
KR101964195B1 (ko) * 2011-06-23 2019-04-01 비아멧 파마슈티컬즈(엔씨), 인코포레이티드 금속효소 억제제 화합물
DK2804858T3 (da) 2012-01-20 2020-03-16 Mycovia Pharmaceuticals Inc Metalloenzym-inhibitorforbindelser
TWI646088B (zh) * 2012-03-16 2019-01-01 維愛美製藥公司 金屬酶抑制劑化合物
WO2013144224A1 (en) * 2012-03-27 2013-10-03 Syngenta Participations Ag Acetylenic microbiocides
WO2015037013A1 (en) * 2013-09-13 2015-03-19 Suven Life Sciences Limited Process for the large scale production of 1h- [1,2,3]triazole and its intermediate 1-benzyl-1h-[1,2,3] triazole

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4729523A (en) * 1984-06-11 1988-03-08 Kabushiki Kaisha Tokai-Rika-Denki-Seisakusho Locking mechanism for webbing retractor
GB8819308D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
GB9107055D0 (en) * 1991-04-04 1991-05-22 Pfizer Ltd Triazole antifungal agents
GB9121456D0 (en) * 1991-10-10 1991-11-27 Pfizer Ltd Triazole antifungal agents
NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
CA2145458A1 (en) * 1994-03-28 1995-09-29 Hiroki Kodama Triazole compound and production process and use thereof

Also Published As

Publication number Publication date
PE4698A1 (es) 1998-03-03
ATE246186T1 (de) 2003-08-15
PL324336A1 (en) 1998-05-25
PT835252E (pt) 2003-11-28
EP0835252A1 (de) 1998-04-15
US6015825A (en) 2000-01-18
NO976047D0 (no) 1997-12-22
GB9512961D0 (en) 1995-08-30
ES2202453T3 (es) 2004-04-01
AR002761A1 (es) 1998-04-29
CO4480719A1 (es) 1997-07-09
NZ311651A (en) 1999-09-29
NO976047L (no) 1998-02-25
JPH10506652A (ja) 1998-06-30
HUP9803022A2 (hu) 1999-10-28
BR9609298A (pt) 1999-05-18
KR19990028390A (ko) 1999-04-15
AU6301096A (en) 1997-01-30
ZA965365B (en) 1997-12-29
WO1997001552A1 (en) 1997-01-16
DE69629300T2 (de) 2004-03-04
EP0835252B1 (de) 2003-07-30
CA2224983A1 (en) 1997-01-16
DK0835252T3 (da) 2003-10-27
MX9800046A (es) 1998-08-30
TR199701699T1 (xx) 1998-06-22
JP3105926B2 (ja) 2000-11-06
IL118698A0 (en) 1996-10-16
AU697405B2 (en) 1998-10-08
CA2224983C (en) 2003-04-08
CZ415597A3 (cs) 1998-11-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PFIZER IRELAND PHARMACEUTICALS, DUN LAOGHAIRE, COU

8339 Ceased/non-payment of the annual fee