DE69627820T2 - Rezeptorspezifischer transepithelialer transport von immunogenen - Google Patents

Rezeptorspezifischer transepithelialer transport von immunogenen Download PDF

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Publication number
DE69627820T2
DE69627820T2 DE69627820T DE69627820T DE69627820T2 DE 69627820 T2 DE69627820 T2 DE 69627820T2 DE 69627820 T DE69627820 T DE 69627820T DE 69627820 T DE69627820 T DE 69627820T DE 69627820 T2 DE69627820 T2 DE 69627820T2
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Prior art keywords
fcrn
igg
antigen
molecule
conjugate
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE69627820T
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German (de)
English (en)
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DE69627820D1 (de
Inventor
S. Richard BLUMBERG
E. Neil SIMISTER
I. Wayne LENCER
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Brandeis University
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Brigham and Womens Hospital Inc
Brandeis University
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Priority claimed from US08/374,159 external-priority patent/US6086875A/en
Application filed by Brigham and Womens Hospital Inc, Brandeis University filed Critical Brigham and Womens Hospital Inc
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Publication of DE69627820D1 publication Critical patent/DE69627820D1/de
Publication of DE69627820T2 publication Critical patent/DE69627820T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K2039/55516—Proteins; Peptides
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    • A61K2039/6031—Proteins
    • A61K2039/6056—Antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurosurgery (AREA)
DE69627820T 1995-01-17 1996-01-17 Rezeptorspezifischer transepithelialer transport von immunogenen Expired - Lifetime DE69627820T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/374,159 US6086875A (en) 1995-01-17 1995-01-17 Receptor specific transepithelial transport of immunogens
US374159 1995-01-17
US57817195A 1995-12-29 1995-12-29
US578171 1995-12-29
PCT/US1996/000597 WO1996022024A1 (en) 1995-01-17 1996-01-17 Receptor specific transepithelial transport of immunogens

Publications (2)

Publication Number Publication Date
DE69627820D1 DE69627820D1 (de) 2003-06-05
DE69627820T2 true DE69627820T2 (de) 2004-04-08

Family

ID=27006452

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69627820T Expired - Lifetime DE69627820T2 (de) 1995-01-17 1996-01-17 Rezeptorspezifischer transepithelialer transport von immunogenen
DE69636312T Expired - Lifetime DE69636312T2 (de) 1995-01-17 1996-01-17 Rezeptorspezifischer Transepithelealer Transport von Immunogenen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69636312T Expired - Lifetime DE69636312T2 (de) 1995-01-17 1996-01-17 Rezeptorspezifischer Transepithelealer Transport von Immunogenen

Country Status (9)

Country Link
EP (3) EP1323346B1 (https=)
JP (2) JP4026848B2 (https=)
AT (2) ATE238668T1 (https=)
CA (1) CA2210656C (https=)
DE (2) DE69627820T2 (https=)
DK (2) DK0805628T3 (https=)
ES (2) ES2268182T3 (https=)
PT (1) PT1323346E (https=)
WO (1) WO1996022024A1 (https=)

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US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
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EP1683865A3 (en) 2001-02-02 2006-10-25 Eli Lilly & Company Mammalian proteins and in particular CD200
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