DE69627277D1 - Verfahren zur Herstellung von Etoposide - Google Patents
Verfahren zur Herstellung von EtoposideInfo
- Publication number
- DE69627277D1 DE69627277D1 DE69627277T DE69627277T DE69627277D1 DE 69627277 D1 DE69627277 D1 DE 69627277D1 DE 69627277 T DE69627277 T DE 69627277T DE 69627277 T DE69627277 T DE 69627277T DE 69627277 D1 DE69627277 D1 DE 69627277D1
- Authority
- DE
- Germany
- Prior art keywords
- etoposide
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33772095 | 1995-12-04 | ||
| JP33772095 | 1995-12-04 | ||
| JP34511495 | 1995-12-08 | ||
| JP34511495 | 1995-12-08 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69627277D1 true DE69627277D1 (de) | 2003-05-15 |
| DE69627277T2 DE69627277T2 (de) | 2004-03-04 |
Family
ID=26575893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69627277T Expired - Lifetime DE69627277T2 (de) | 1995-12-04 | 1996-12-03 | Verfahren zur Herstellung von Etoposide |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5821348A (de) |
| EP (1) | EP0778282B1 (de) |
| KR (1) | KR100414706B1 (de) |
| CN (1) | CN1067402C (de) |
| AU (1) | AU712060B2 (de) |
| DE (1) | DE69627277T2 (de) |
| ES (1) | ES2191733T3 (de) |
| IL (1) | IL119749A (de) |
| TW (1) | TW416959B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2343803A1 (en) | 1998-09-10 | 2000-03-23 | Ragina Naidu | Synthetic method for the preparation of the antineoplastic agent etoposide |
| EP2266607A3 (de) | 1999-10-01 | 2011-04-20 | Immunogen, Inc. | Immunokonjugate für Krebsbehandlung |
| CN1101819C (zh) * | 1999-10-21 | 2003-02-19 | 国家医药管理局上海医药工业研究院 | 具有抗肿瘤活性的4－β－碳取代－4－脱氧－4'－去甲表鬼臼毒素衍生物及合成方法和中间体 |
| AU2002222695A1 (en) | 2000-11-20 | 2002-05-27 | Song-Bae Kim | Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same |
| CN105566412A (zh) * | 2016-01-18 | 2016-05-11 | 江西师范大学 | 一种依托泊苷和替尼泊苷及其类似物的制备方法 |
| CN112079879B (zh) * | 2020-08-21 | 2022-01-14 | 华润双鹤药业股份有限公司沧州分公司 | 一种替尼泊苷中间体的合成新方法及替尼泊苷的合成方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60246393A (ja) * | 1984-05-22 | 1985-12-06 | Nippon Kayaku Co Ltd | エトポシドの新規製造法 |
| DE3913326A1 (de) | 1989-04-22 | 1990-11-08 | Behringwerke Ag | Verfahren zur herstellung von etoposiden |
| DE3913327A1 (de) * | 1989-04-22 | 1990-10-25 | Behringwerke Ag | Verfahren zur herstellung von glucosaminyl-epi-podo-phyllotoxin-derivaten |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| CA2017916C (en) * | 1989-06-07 | 1999-02-02 | Minoru Aoki | Etoposide preparations |
| IT1250692B (it) * | 1991-07-23 | 1995-04-21 | Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi. | |
| US5459248A (en) * | 1993-11-04 | 1995-10-17 | Bristol-Myers Squibb Company | Process of preparing etoposide phosphate and etoposide |
-
1996
- 1996-12-03 EP EP96119336A patent/EP0778282B1/de not_active Expired - Lifetime
- 1996-12-03 ES ES96119336T patent/ES2191733T3/es not_active Expired - Lifetime
- 1996-12-03 DE DE69627277T patent/DE69627277T2/de not_active Expired - Lifetime
- 1996-12-03 IL IL11974996A patent/IL119749A/xx not_active IP Right Cessation
- 1996-12-04 US US08/760,647 patent/US5821348A/en not_active Expired - Lifetime
- 1996-12-04 CN CN96121862A patent/CN1067402C/zh not_active Expired - Lifetime
- 1996-12-04 KR KR1019960061554A patent/KR100414706B1/ko not_active IP Right Cessation
- 1996-12-04 AU AU74141/96A patent/AU712060B2/en not_active Ceased
- 1996-12-04 TW TW085114942A patent/TW416959B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU712060B2 (en) | 1999-10-28 |
| US5821348A (en) | 1998-10-13 |
| CN1154968A (zh) | 1997-07-23 |
| CN1067402C (zh) | 2001-06-20 |
| EP0778282B1 (de) | 2003-04-09 |
| ES2191733T3 (es) | 2003-09-16 |
| IL119749A (en) | 2001-03-19 |
| TW416959B (en) | 2001-01-01 |
| KR970042580A (ko) | 1997-07-24 |
| DE69627277T2 (de) | 2004-03-04 |
| IL119749A0 (en) | 1997-03-18 |
| EP0778282A1 (de) | 1997-06-11 |
| AU7414196A (en) | 1997-06-12 |
| KR100414706B1 (ko) | 2004-07-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69628712D1 (de) | Verfahren zur Herstellung von Dihalogenazolopyrimidinen | |
| DE69615453T2 (de) | Verfahren zur Herstellung von mikrokapselhaltigen Zusammensetzungen | |
| DE59607656D1 (de) | Verfahren zur Herstellung von Alkylhydrogenchlorsilanen | |
| DE69619067T2 (de) | Verfahren zur Herstellung von 3-Amino-2-oxo-1-Halogenpropan-Derivaten | |
| DE59603916D1 (de) | Verfahren zur Herstellung von Imidazo-Benzodiazepin-Derivaten | |
| DE69616452T2 (de) | Verfahren zur Herstellung von Sulfonylharnstoffen | |
| DE69625253D1 (de) | Verfahren zur Herstellung von Imidazochinazolinon-Derivaten | |
| DE69606102D1 (de) | Verfahren zur Herstellung von Difluormethan | |
| DE69635421D1 (de) | Verfahren zur herstellung von 2-chlorthiazolderivaten | |
| DE59601030D1 (de) | Verfahren zur Herstellung von Diarylethanen | |
| DE69600385D1 (de) | Verfahren zur Herstellung von Aminonitropyridinen | |
| DE69627277D1 (de) | Verfahren zur Herstellung von Etoposide | |
| DE69611331T2 (de) | Verfahren zur Herstellung von S-Phenyl-L-Cystein | |
| DE69625102D1 (de) | Verfahren zur Herstellung von 3-Methyltetrahydrofuran | |
| DE69513008D1 (de) | Verfahren zur Herstellung von Hydroxyalkoxybenzophenonen | |
| DE69607541D1 (de) | Verfahren zur Herstellung von p-Bromfluorobenzol | |
| DE59605105D1 (de) | Verfahren zur Herstellung von substituierten Aminocarbonyltriazolinonen | |
| DE69603243D1 (de) | Verfahren zur Herstellung von Ethenylamiden | |
| DE69607290D1 (de) | Verfahren zur Herstellung von Lactamid | |
| DE59605227D1 (de) | Verfahren zur Herstellung von ortho-Nitro-benzonitrilen | |
| DE69616195T2 (de) | Verfahren zur Herstellung von 4-tert-Butylcyclohexanol | |
| DE59604010D1 (de) | Verfahren zur Herstellung von 3-hydroxyoxetanen | |
| DE59601809D1 (de) | Verfahren zur Herstellung von substituierten Aminotriazolinonen | |
| DE59604167D1 (de) | Verfahren zur Herstellung von primären Octadienylaminen | |
| DE59607076D1 (de) | Verfahren zur Herstellung von 2-Amino-6-chlorphenyl-isopropylsulfan |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |