DE69619861T2 - 3-(2h)-pyridazinon derivate und diese verbindungen enthaltende pharmazeutische zusammensetzungen - Google Patents
3-(2h)-pyridazinon derivate und diese verbindungen enthaltende pharmazeutische zusammensetzungenInfo
- Publication number
- DE69619861T2 DE69619861T2 DE69619861T DE69619861T DE69619861T2 DE 69619861 T2 DE69619861 T2 DE 69619861T2 DE 69619861 T DE69619861 T DE 69619861T DE 69619861 T DE69619861 T DE 69619861T DE 69619861 T2 DE69619861 T2 DE 69619861T2
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- pharmaceutical compositions
- compositions containing
- pyridazinone
- pyridazinone derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
- FJNRJBQUOQLUNQ-CYBMUJFWSA-N 2-[3-[[(3r)-2,3-dihydro-1,4-benzodioxin-3-yl]methylamino]propyl]pyridazin-3-one Chemical compound O=C1C=CC=NN1CCCNC[C@H]1OC2=CC=CC=C2OC1 FJNRJBQUOQLUNQ-CYBMUJFWSA-N 0.000 abstract 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- 108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 abstract 1
- 108020004101 alpha-2 Adrenergic Receptor Proteins 0.000 abstract 1
- 102000015009 alpha1-adrenergic receptor activity proteins Human genes 0.000 abstract 1
- 102000015006 alpha2-adrenergic receptor activity proteins Human genes 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU9501560A HU224067B1 (hu) | 1995-05-29 | 1995-05-29 | 3(2H)-Piridazinon-származékok és e vegyületeket tartalmazó gyógyszerkészítmények |
PCT/HU1996/000030 WO1996038441A1 (en) | 1995-05-29 | 1996-05-28 | 3(2h)-pyridazinone derivatives and pharmaceutical compositions containing these compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69619861D1 DE69619861D1 (de) | 2002-04-18 |
DE69619861T2 true DE69619861T2 (de) | 2002-09-26 |
Family
ID=10986884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69619861T Expired - Fee Related DE69619861T2 (de) | 1995-05-29 | 1996-05-28 | 3-(2h)-pyridazinon derivate und diese verbindungen enthaltende pharmazeutische zusammensetzungen |
Country Status (13)
Country | Link |
---|---|
US (2) | US6194411B1 (de) |
EP (1) | EP0869957B1 (de) |
JP (2) | JP3857313B2 (de) |
KR (1) | KR100408364B1 (de) |
AT (1) | ATE214389T1 (de) |
AU (1) | AU710265B2 (de) |
CA (1) | CA2222724C (de) |
DE (1) | DE69619861T2 (de) |
DK (1) | DK0869957T3 (de) |
ES (1) | ES2175100T3 (de) |
HU (1) | HU224067B1 (de) |
PT (1) | PT869957E (de) |
WO (1) | WO1996038441A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU227237B1 (en) * | 2001-09-27 | 2010-12-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Substituted alkylpyridazinone derivatives, process for their preparation, pharmaceutical compositions containing them |
WO2006089053A2 (en) | 2005-02-17 | 2006-08-24 | Wyeth | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU195645B (en) * | 1985-10-30 | 1988-06-28 | Gyogyszerkutato Intezet | Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same |
-
1995
- 1995-05-29 HU HU9501560A patent/HU224067B1/hu not_active IP Right Cessation
-
1996
- 1996-05-28 ES ES96919967T patent/ES2175100T3/es not_active Expired - Lifetime
- 1996-05-28 DE DE69619861T patent/DE69619861T2/de not_active Expired - Fee Related
- 1996-05-28 DK DK96919967T patent/DK0869957T3/da active
- 1996-05-28 PT PT96919967T patent/PT869957E/pt unknown
- 1996-05-28 AT AT96919967T patent/ATE214389T1/de not_active IP Right Cessation
- 1996-05-28 CA CA002222724A patent/CA2222724C/en not_active Expired - Fee Related
- 1996-05-28 JP JP53631996A patent/JP3857313B2/ja not_active Expired - Fee Related
- 1996-05-28 WO PCT/HU1996/000030 patent/WO1996038441A1/en active IP Right Grant
- 1996-05-28 AU AU58427/96A patent/AU710265B2/en not_active Ceased
- 1996-05-28 EP EP96919967A patent/EP0869957B1/de not_active Expired - Lifetime
- 1996-05-28 US US08/973,584 patent/US6194411B1/en not_active Expired - Fee Related
- 1996-05-28 KR KR1019970708521A patent/KR100408364B1/ko not_active IP Right Cessation
-
2000
- 2000-08-28 US US09/649,077 patent/US6248907B1/en not_active Expired - Fee Related
-
2006
- 2006-06-01 JP JP2006153349A patent/JP2006316064A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR100408364B1 (ko) | 2004-06-14 |
ES2175100T3 (es) | 2002-11-16 |
EP0869957A2 (de) | 1998-10-14 |
AU5842796A (en) | 1996-12-18 |
PT869957E (pt) | 2002-09-30 |
HUT75104A (en) | 1997-04-28 |
JP2006316064A (ja) | 2006-11-24 |
WO1996038441A1 (en) | 1996-12-05 |
JPH11506094A (ja) | 1999-06-02 |
HU224067B1 (hu) | 2005-05-30 |
US6194411B1 (en) | 2001-02-27 |
KR19990022042A (ko) | 1999-03-25 |
CA2222724A1 (en) | 1996-12-05 |
HU9501560D0 (en) | 1995-07-28 |
EP0869957B1 (de) | 2002-03-13 |
AU710265B2 (en) | 1999-09-16 |
DE69619861D1 (de) | 2002-04-18 |
CA2222724C (en) | 2006-05-23 |
ATE214389T1 (de) | 2002-03-15 |
US6248907B1 (en) | 2001-06-19 |
JP3857313B2 (ja) | 2006-12-13 |
DK0869957T3 (da) | 2002-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: IVAX DRUG RESEARCH INSTITUTE LTD., BUDAPEST, HU |
|
8339 | Ceased/non-payment of the annual fee |