DE69615498T2 - Benzensulfonamidderivate als bradykinin antagonisten - Google Patents
Benzensulfonamidderivate als bradykinin antagonistenInfo
- Publication number
- DE69615498T2 DE69615498T2 DE69615498T DE69615498T DE69615498T2 DE 69615498 T2 DE69615498 T2 DE 69615498T2 DE 69615498 T DE69615498 T DE 69615498T DE 69615498 T DE69615498 T DE 69615498T DE 69615498 T2 DE69615498 T2 DE 69615498T2
- Authority
- DE
- Germany
- Prior art keywords
- pct
- nr4r5
- sec
- different
- date
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9506703A FR2735128B1 (fr) | 1995-06-07 | 1995-06-07 | Nouveaux composes de benzenesulfonamide, leur procede de preparation et utilisation en therapeutique. |
PCT/FR1996/000845 WO1996040639A1 (fr) | 1995-06-07 | 1996-06-05 | Derives de benzenesulfonamide comme antagonistes de la bradykinine |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69615498D1 DE69615498D1 (de) | 2001-10-31 |
DE69615498T2 true DE69615498T2 (de) | 2002-05-16 |
Family
ID=9479700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69615498T Expired - Fee Related DE69615498T2 (de) | 1995-06-07 | 1996-06-05 | Benzensulfonamidderivate als bradykinin antagonisten |
Country Status (10)
Country | Link |
---|---|
US (1) | US5968951A (de) |
EP (1) | EP0773932B1 (de) |
JP (1) | JPH10504840A (de) |
AT (1) | ATE206114T1 (de) |
DE (1) | DE69615498T2 (de) |
DK (1) | DK0773932T3 (de) |
ES (1) | ES2164896T3 (de) |
FR (1) | FR2735128B1 (de) |
PT (1) | PT773932E (de) |
WO (1) | WO1996040639A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19609827A1 (de) * | 1996-03-13 | 1997-09-18 | Hoechst Ag | Aminoalkyl- und Acylaminoalkylether, Verfahren zu deren Herstellung und ihre Verwendung als Bradykinin-Rezeptorantagonisten |
FR2751650B1 (fr) * | 1996-07-24 | 1998-10-09 | Fournier Ind & Sante | Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique |
DE19712960A1 (de) * | 1997-03-27 | 1998-10-01 | Hoechst Ag | Benzyloxy-substituierte, anellierte N-Heterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Bradykininrezeptorantagonisten |
FR2765222B1 (fr) * | 1997-06-27 | 1999-12-31 | Fournier Ind & Sante | Nouveaux composes de n-benzenesulfonyl-l-proline, procede de preparation et utilisation en therapeutique |
FR2790260B1 (fr) | 1999-02-26 | 2001-05-04 | Fournier Ind & Sante | Nouveaux composes de n-(benzenesulfonamide), procede de preparation et utilisation en therapeutique |
US7105172B1 (en) | 1999-11-18 | 2006-09-12 | Bolla John D | Treatment of rosacea |
US6699486B1 (en) | 1999-11-18 | 2004-03-02 | Bolla Corporation | Treatment or prevention of photoaging and skin cancer |
FR2819254B1 (fr) * | 2001-01-08 | 2003-04-18 | Fournier Lab Sa | Nouveaux composes de la n-(phenylsulfonyl) glycine, leur procede de preparation et leur utilisation pour obtenir des compostions pharmaceutiques |
FR2822827B1 (fr) * | 2001-03-28 | 2003-05-16 | Sanofi Synthelabo | Nouveaux derives de n-(arylsulfonyl) beta-aminoacides comportant un groupe aminomethyle substitue, leur procede de preparation et les compositions pharmaceutiques en contenant |
EP1914236A1 (de) | 2002-04-10 | 2008-04-23 | Ortho-McNeil Pharmaceutical, Inc. | Neue Heteroaryl-Alkylamid-Derivate als Bradykininrezeptormodulatoren |
WO2003093245A1 (en) * | 2002-05-03 | 2003-11-13 | Elan Pharmaceuticals, Inc. | Sulfonylquinoxalone acetamide derivatives and related compounds as bradykinin antagonists |
ITMI20021247A1 (it) * | 2002-06-07 | 2003-12-09 | Menarini Ricerche Spa | Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche |
FR2840897B1 (fr) | 2002-06-14 | 2004-09-10 | Fournier Lab Sa | Nouveaux derives d'arylsulfonamides et leur utilisation en therapeutique |
US20050020591A1 (en) * | 2002-12-13 | 2005-01-27 | Dai-Shi Su | 2-Quinoxalinone derivatives as bradykinin antagonists and novel compounds |
EA008921B1 (ru) | 2003-03-25 | 2007-08-31 | Лаборатуар Фурнье С.А. | Производные бензолсульфонамидов, способ их получения и их применение для лечения боли |
JP2010527401A (ja) * | 2007-05-14 | 2010-08-12 | タイコ ヘルスケア グループ リミテッド パートナーシップ | 抗菌材料および被膜 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2533821A1 (de) * | 1975-07-29 | 1977-02-17 | Hoechst Ag | Thiazolidinderivate und verfahren zu ihrer herstellung |
DE3632329A1 (de) * | 1986-09-24 | 1988-03-31 | Bayer Ag | Substituierte phenylsulfonamide |
US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US5212182A (en) * | 1990-10-03 | 1993-05-18 | American Home Products Corpooration | Substituted quinolinyl- and naphthalenylbenzamides or benzylamines and related compounds useful as analgesics |
AU686115B2 (en) * | 1992-11-02 | 1998-02-05 | Fujisawa Pharmaceutical Co., Ltd. | Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation |
AU680870B2 (en) * | 1993-04-28 | 1997-08-14 | Astellas Pharma Inc. | New heterocyclic compounds |
-
1995
- 1995-06-07 FR FR9506703A patent/FR2735128B1/fr not_active Expired - Fee Related
-
1996
- 1996-06-05 PT PT96920901T patent/PT773932E/pt unknown
- 1996-06-05 AT AT96920901T patent/ATE206114T1/de not_active IP Right Cessation
- 1996-06-05 ES ES96920901T patent/ES2164896T3/es not_active Expired - Lifetime
- 1996-06-05 DK DK96920901T patent/DK0773932T3/da active
- 1996-06-05 US US08/776,544 patent/US5968951A/en not_active Expired - Fee Related
- 1996-06-05 DE DE69615498T patent/DE69615498T2/de not_active Expired - Fee Related
- 1996-06-05 EP EP96920901A patent/EP0773932B1/de not_active Expired - Lifetime
- 1996-06-05 JP JP9500190A patent/JPH10504840A/ja not_active Ceased
- 1996-06-05 WO PCT/FR1996/000845 patent/WO1996040639A1/fr active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
DK0773932T3 (da) | 2002-01-14 |
JPH10504840A (ja) | 1998-05-12 |
FR2735128B1 (fr) | 1997-07-25 |
EP0773932A1 (de) | 1997-05-21 |
US5968951A (en) | 1999-10-19 |
WO1996040639A1 (fr) | 1996-12-19 |
FR2735128A1 (fr) | 1996-12-13 |
DE69615498D1 (de) | 2001-10-31 |
ES2164896T3 (es) | 2002-03-01 |
EP0773932B1 (de) | 2001-09-26 |
ATE206114T1 (de) | 2001-10-15 |
PT773932E (pt) | 2002-03-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |