DE69533189T2 - Immuntherapie von krebs mit allogenen lymphocyten - Google Patents
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- DE69533189T2 DE69533189T2 DE69533189T DE69533189T DE69533189T2 DE 69533189 T2 DE69533189 T2 DE 69533189T2 DE 69533189 T DE69533189 T DE 69533189T DE 69533189 T DE69533189 T DE 69533189T DE 69533189 T2 DE69533189 T2 DE 69533189T2
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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- Organic Chemistry (AREA)
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- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21494494A | 1994-03-17 | 1994-03-17 | |
| US214944 | 1994-03-17 | ||
| PCT/US1995/003303 WO1995024910A1 (en) | 1994-03-17 | 1995-03-16 | Immunotherapy of cancer with allogeneic lymphocytes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69533189D1 DE69533189D1 (de) | 2004-07-29 |
| DE69533189T2 true DE69533189T2 (de) | 2005-07-21 |
Family
ID=22801017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69533189T Expired - Lifetime DE69533189T2 (de) | 1994-03-17 | 1995-03-16 | Immuntherapie von krebs mit allogenen lymphocyten |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5843435A (enExample) |
| EP (1) | EP0750505B1 (enExample) |
| JP (1) | JPH09510456A (enExample) |
| AU (1) | AU2100695A (enExample) |
| CA (1) | CA2184352A1 (enExample) |
| DE (1) | DE69533189T2 (enExample) |
| ES (1) | ES2224122T3 (enExample) |
| IL (1) | IL112969A (enExample) |
| WO (1) | WO1995024910A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
| JPH11511746A (ja) * | 1995-05-25 | 1999-10-12 | バクスター、インターナショナル、インコーポレイテッド | 同種幹細胞移植後の癌の同種細胞治療 |
| US5800539A (en) * | 1995-11-08 | 1998-09-01 | Emory University | Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease |
| CA2243235C (en) * | 1996-01-17 | 2010-08-10 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
| US6213127B1 (en) | 1996-07-29 | 2001-04-10 | Emory University | Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity |
| US5834487A (en) * | 1996-09-24 | 1998-11-10 | Cv Therapeutics | Inhibition of 26S and 20S proteasome by indanones |
| JP2002514193A (ja) | 1996-11-15 | 2002-05-14 | バクスター、インターナショナル、インコーポレイテッド | 同種幹細胞移植のためのコンディショニング |
| US6428782B1 (en) * | 1997-05-23 | 2002-08-06 | Hadasit Medical Research Services And Development Ltd. | Non-myeloablative tolerogenic treatment |
| CA2346735C (en) * | 1997-10-10 | 2005-01-25 | Meyer Pharmaceuticals, Llc | Cancer immunotherapy using allostimulated cells in a multiple sequential implantation strategy |
| US20040033230A1 (en) * | 1997-12-24 | 2004-02-19 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US7598226B2 (en) | 1998-12-28 | 2009-10-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US6969518B2 (en) * | 1998-12-28 | 2005-11-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| AU1807401A (en) * | 1999-11-30 | 2001-06-12 | Corixa Corporation | Compositions and methods for therapy and diagnosis of breast cancer |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| JP4917201B2 (ja) * | 2000-12-04 | 2012-04-18 | 株式会社リンフォテック | 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。 |
| KR20020060643A (ko) * | 2002-06-04 | 2002-07-18 | 김진경 | 타인의 면역시스템을 이용하는 암의 치료 방법 |
| US20040175373A1 (en) * | 2002-06-28 | 2004-09-09 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| US20040151704A1 (en) * | 2002-06-28 | 2004-08-05 | Xcyte Therapies, Inc. | Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| WO2005021734A2 (en) * | 2003-09-02 | 2005-03-10 | University Of Massachussets | Generation of hematopoietic chimerism and induction of central tolerance |
| US20050186146A1 (en) * | 2004-02-12 | 2005-08-25 | Nektar Therapeutics | Interleukin-13 antagonist powders, spray-dried particles, and methods |
| WO2006004592A2 (en) * | 2004-05-28 | 2006-01-12 | Mayo Foundation For Medical Education And Research | Methods for autologous stem cell transplantation |
| US9155789B2 (en) * | 2005-04-25 | 2015-10-13 | New York University | Use of allogenic or syngenic major histocompatibility complex (MHC) molecules as universal adjuvants for vaccines against neoplastic disease, infection and autoimmune disease |
| JP5638804B2 (ja) | 2006-08-04 | 2014-12-10 | アストラゼネカ アクチボラグ | ＥｒｂＢ２に対する抗体 |
| PL2068930T3 (pl) | 2006-08-07 | 2013-02-28 | Abbvie Biotherapeutics Inc | Kompozycje i sposoby wykorzystujące przeciwciało anty-CS1 do leczenia szpiczaka mnogiego |
| PT2641601T (pt) | 2006-08-07 | 2016-10-14 | Dana Farber Cancer Inst Inc | Métodos de tratamento de mieloma múltiplo utilizando terapias de combinação baseadas em huluc63 com bortezomib |
| CA2668673A1 (en) * | 2006-11-08 | 2008-05-22 | Aldagen, Inc. | Methods for improved engraftment following stem cell transplantation |
| WO2008067126A2 (en) * | 2006-11-08 | 2008-06-05 | Aldagen, Inc. | Methods for using aldhbr cells to supplement stem cell transplantation |
| WO2011021503A1 (ja) * | 2009-08-17 | 2011-02-24 | 国立大学法人東京大学 | 一過性生着ｃｔｌを含む医薬品組成物 |
| KR20140105848A (ko) * | 2011-12-22 | 2014-09-02 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | Ｔ/ｂ 세포 제거를 위한 특정 프로토콜을 이용하는, 안정하고 장기적인 생착을 위한 병용 치료법 |
| WO2016054354A1 (en) | 2014-10-02 | 2016-04-07 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating malignancies |
| US10302644B2 (en) | 2014-11-04 | 2019-05-28 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating multiple myeloma |
| AU2018234827B2 (en) | 2017-03-15 | 2024-04-04 | Orca Biosystems Inc. | Compositions and methods for hematopoietic stem cell transplants |
| EP4165084A4 (en) | 2020-06-14 | 2025-03-19 | Shimon Slavin | Multifunctional immunotherapeutic monoclonal antibody complexes and conjugates |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4690915A (en) * | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4861589A (en) * | 1987-03-23 | 1989-08-29 | Trustees Of Boston University | Method for therapeutically treating abnormal cells expressing a major histocompatibility complex class II antigen using cytolytic inducer T4 cells |
| US5126132A (en) * | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| JPH07102131B2 (ja) * | 1991-07-15 | 1995-11-08 | 日本石油株式会社 | ヒトリンパ球の癌細胞に対する傷害活性を高める方法 |
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
-
1995
- 1995-03-13 IL IL11296995A patent/IL112969A/en not_active IP Right Cessation
- 1995-03-16 DE DE69533189T patent/DE69533189T2/de not_active Expired - Lifetime
- 1995-03-16 JP JP7524180A patent/JPH09510456A/ja active Pending
- 1995-03-16 ES ES95913730T patent/ES2224122T3/es not_active Expired - Lifetime
- 1995-03-16 AU AU21006/95A patent/AU2100695A/en not_active Abandoned
- 1995-03-16 WO PCT/US1995/003303 patent/WO1995024910A1/en not_active Ceased
- 1995-03-16 CA CA002184352A patent/CA2184352A1/en not_active Abandoned
- 1995-03-16 EP EP95913730A patent/EP0750505B1/en not_active Expired - Lifetime
- 1995-03-16 US US08/714,144 patent/US5843435A/en not_active Expired - Lifetime
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1996
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2001
- 2001-12-03 US US10/005,747 patent/US20020176850A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US5843435A (en) | 1998-12-01 |
| ES2224122T3 (es) | 2005-03-01 |
| JPH09510456A (ja) | 1997-10-21 |
| DE69533189D1 (de) | 2004-07-29 |
| WO1995024910A1 (en) | 1995-09-21 |
| MX9604099A (es) | 1997-09-30 |
| CA2184352A1 (en) | 1995-09-21 |
| EP0750505B1 (en) | 2004-06-23 |
| AU2100695A (en) | 1995-10-03 |
| US20020176850A1 (en) | 2002-11-28 |
| IL112969A (en) | 2001-05-20 |
| IL112969A0 (en) | 1995-06-29 |
| EP0750505A1 (en) | 1997-01-02 |
| US5928639A (en) | 1999-07-27 |
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| 8364 | No opposition during term of opposition |