IL112969A - Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator - Google Patents
Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activatorInfo
- Publication number
- IL112969A IL112969A IL11296995A IL11296995A IL112969A IL 112969 A IL112969 A IL 112969A IL 11296995 A IL11296995 A IL 11296995A IL 11296995 A IL11296995 A IL 11296995A IL 112969 A IL112969 A IL 112969A
- Authority
- IL
- Israel
- Prior art keywords
- patient
- cells
- cell
- lymphocytes
- allogeneic
- Prior art date
Links
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
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- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- A61K40/00—Cellular immunotherapy
- A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Wood Science & Technology (AREA)
- Microbiology (AREA)
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- Hematology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21494494A | 1994-03-17 | 1994-03-17 |
Publications (2)
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| IL112969A0 IL112969A0 (en) | 1995-06-29 |
| IL112969A true IL112969A (en) | 2001-05-20 |
Family
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Family Applications (1)
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| IL11296995A IL112969A (en) | 1994-03-17 | 1995-03-13 | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
Country Status (9)
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| EP (1) | EP0750505B1 (enExample) |
| JP (1) | JPH09510456A (enExample) |
| AU (1) | AU2100695A (enExample) |
| CA (1) | CA2184352A1 (enExample) |
| DE (1) | DE69533189T2 (enExample) |
| ES (1) | ES2224122T3 (enExample) |
| IL (1) | IL112969A (enExample) |
| WO (1) | WO1995024910A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
| US6143292A (en) * | 1995-05-25 | 2000-11-07 | Baxter International Inc. | Allogeneic cell therapy for cancer following allogeneic stem cell transplantation |
| US5800539A (en) * | 1995-11-08 | 1998-09-01 | Emory University | Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease |
| US6805861B2 (en) * | 1996-01-17 | 2004-10-19 | Imperial College Innovations Limited | Immunotherapy using cytotoxic T lymphocytes (CTL) |
| US6213127B1 (en) | 1996-07-29 | 2001-04-10 | Emory University | Methods for treating cancer using allogeneic lymphocytes without graft vs host disease activity |
| US5834487A (en) * | 1996-09-24 | 1998-11-10 | Cv Therapeutics | Inhibition of 26S and 20S proteasome by indanones |
| IL129573A0 (en) * | 1996-11-15 | 2000-02-29 | Baxter Int | Conditioning for allogeneic stem cell transplantation |
| US6428782B1 (en) * | 1997-05-23 | 2002-08-06 | Hadasit Medical Research Services And Development Ltd. | Non-myeloablative tolerogenic treatment |
| AU9589398A (en) * | 1997-10-10 | 1999-05-03 | Applied Immunotherapeutics, Inc. | Cancer immunotherapy using allostimulated cells in a multiple sequential implantation strategy |
| US20040033230A1 (en) * | 1997-12-24 | 2004-02-19 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US7598226B2 (en) | 1998-12-28 | 2009-10-06 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| US6969518B2 (en) * | 1998-12-28 | 2005-11-29 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of breast cancer |
| AU1807401A (en) * | 1999-11-30 | 2001-06-12 | Corixa Corporation | Compositions and methods for therapy and diagnosis of breast cancer |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US7541184B2 (en) | 2000-02-24 | 2009-06-02 | Invitrogen Corporation | Activation and expansion of cells |
| JP4917201B2 (ja) * | 2000-12-04 | 2012-04-18 | 株式会社リンフォテック | 臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤、臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤、臍帯血移植後の腫瘍および各種感染症の予防・治療用製剤ならびに臍帯血移植後の移植臍帯血幹細胞の生着促進用製剤の製造方法。 |
| KR20020060643A (ko) * | 2002-06-04 | 2002-07-18 | 김진경 | 타인의 면역시스템을 이용하는 암의 치료 방법 |
| ES2422193T3 (es) * | 2002-06-28 | 2013-09-09 | Life Technologies Corp | Métodos para restaurar el repertorio inmune en pacientes con defectos inmunológicos relacionados con la autoinmunidad y trasplante de órganos o de células madre hematopoyéticas |
| US20050084967A1 (en) | 2002-06-28 | 2005-04-21 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| US20040175373A1 (en) * | 2002-06-28 | 2004-09-09 | Xcyte Therapies, Inc. | Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation |
| WO2005021734A2 (en) * | 2003-09-02 | 2005-03-10 | University Of Massachussets | Generation of hematopoietic chimerism and induction of central tolerance |
| CA2555841A1 (en) * | 2004-02-12 | 2005-09-01 | Nektar Therapeutics | Interleukin-13 antagonist powders, spray-dried particles, and methods |
| WO2006004592A2 (en) * | 2004-05-28 | 2006-01-12 | Mayo Foundation For Medical Education And Research | Methods for autologous stem cell transplantation |
| US9155789B2 (en) * | 2005-04-25 | 2015-10-13 | New York University | Use of allogenic or syngenic major histocompatibility complex (MHC) molecules as universal adjuvants for vaccines against neoplastic disease, infection and autoimmune disease |
| KR20090058512A (ko) | 2006-08-04 | 2009-06-09 | 아스트라제네카 아베 | Ｅｒｂｂ2에 대한 인간 항체 |
| AU2007281684C1 (en) | 2006-08-07 | 2013-12-19 | Abbvie Biotherapeutics Inc. | Methods of treating multiple myeloma using combination therapies based on anti-CS1 antibodies |
| AU2007281682B2 (en) | 2006-08-07 | 2013-05-16 | Abbvie Biotherapeutics Inc. | Compositions and methods using anti-CS1 antibodies to treat multiple myeloma |
| JP2010508854A (ja) * | 2006-11-08 | 2010-03-25 | アルダジェン， インコーポレイテッド | 幹細胞移植の後の生着を改善するための方法 |
| CA2668608A1 (en) * | 2006-11-08 | 2008-06-05 | Aldagen, Inc. | Methods for using aldhbr cells to supplement stem cell transplantation |
| CN102596209A (zh) * | 2009-08-17 | 2012-07-18 | 国立大学法人东京大学 | 含有短暂性存活ctl的医药品组合物 |
| RU2657758C2 (ru) | 2011-12-22 | 2018-06-15 | Иеда Рисеч Энд Девелопмент Ко. Лтд. | Комбинированная терапия для стабильного и долговременного приживления трансплантата |
| US10365280B2 (en) | 2014-10-02 | 2019-07-30 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating malignancies |
| WO2016073184A1 (en) | 2014-11-04 | 2016-05-12 | Dana Farber Cancer Institute, Inc. | Compositions and methods for treating multiple myeloma |
| CN118662615A (zh) | 2017-03-15 | 2024-09-20 | 浩康生物系统公司 | 用于造血干细胞移植的组合物和方法 |
| US12594341B2 (en) | 2020-06-14 | 2026-04-07 | Shimon Slavin | Multifunctional immunotherapeutic monoclonal antibody complexes and conjugates |
Family Cites Families (5)
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|---|---|---|---|---|
| US4690915A (en) * | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4861589A (en) * | 1987-03-23 | 1989-08-29 | Trustees Of Boston University | Method for therapeutically treating abnormal cells expressing a major histocompatibility complex class II antigen using cytolytic inducer T4 cells |
| US5126132A (en) * | 1989-08-21 | 1992-06-30 | The United States Of America As Represented By The Department Of Health And Human Services | Tumor infiltrating lymphocytes as a treatment modality for human cancer |
| JPH07102131B2 (ja) * | 1991-07-15 | 1995-11-08 | 日本石油株式会社 | ヒトリンパ球の癌細胞に対する傷害活性を高める方法 |
| IL112969A (en) * | 1994-03-17 | 2001-05-20 | Baxter Int | Pharmaceutical compositions for the treatment of cancer comprising allogenic lymphocytes or their combination with a t-cell activator |
-
1995
- 1995-03-13 IL IL11296995A patent/IL112969A/en not_active IP Right Cessation
- 1995-03-16 JP JP7524180A patent/JPH09510456A/ja active Pending
- 1995-03-16 CA CA002184352A patent/CA2184352A1/en not_active Abandoned
- 1995-03-16 WO PCT/US1995/003303 patent/WO1995024910A1/en not_active Ceased
- 1995-03-16 AU AU21006/95A patent/AU2100695A/en not_active Abandoned
- 1995-03-16 DE DE69533189T patent/DE69533189T2/de not_active Expired - Lifetime
- 1995-03-16 ES ES95913730T patent/ES2224122T3/es not_active Expired - Lifetime
- 1995-03-16 US US08/714,144 patent/US5843435A/en not_active Expired - Lifetime
- 1995-03-16 EP EP95913730A patent/EP0750505B1/en not_active Expired - Lifetime
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1996
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2001
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Also Published As
| Publication number | Publication date |
|---|---|
| JPH09510456A (ja) | 1997-10-21 |
| EP0750505A1 (en) | 1997-01-02 |
| IL112969A0 (en) | 1995-06-29 |
| DE69533189T2 (de) | 2005-07-21 |
| AU2100695A (en) | 1995-10-03 |
| US5843435A (en) | 1998-12-01 |
| ES2224122T3 (es) | 2005-03-01 |
| DE69533189D1 (de) | 2004-07-29 |
| MX9604099A (es) | 1997-09-30 |
| US20020176850A1 (en) | 2002-11-28 |
| EP0750505B1 (en) | 2004-06-23 |
| WO1995024910A1 (en) | 1995-09-21 |
| US5928639A (en) | 1999-07-27 |
| CA2184352A1 (en) | 1995-09-21 |
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