DE69530408D1 - Neue zwischenprodukte und verfahren zur herstellung von pyridin-derivaten - Google Patents

Neue zwischenprodukte und verfahren zur herstellung von pyridin-derivaten

Info

Publication number
DE69530408D1
DE69530408D1 DE69530408T DE69530408T DE69530408D1 DE 69530408 D1 DE69530408 D1 DE 69530408D1 DE 69530408 T DE69530408 T DE 69530408T DE 69530408 T DE69530408 T DE 69530408T DE 69530408 D1 DE69530408 D1 DE 69530408D1
Authority
DE
Germany
Prior art keywords
production
intermediate products
pyridine derivatives
new intermediate
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69530408T
Other languages
English (en)
Other versions
DE69530408T2 (de
Inventor
Syotaro Watanabe
R Kem
Ju Lee
Makoto Kajitani
Kazuo Maruhashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
University of Florida
Original Assignee
Taiho Pharmaceutical Co Ltd
University of Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd, University of Florida filed Critical Taiho Pharmaceutical Co Ltd
Publication of DE69530408D1 publication Critical patent/DE69530408D1/de
Application granted granted Critical
Publication of DE69530408T2 publication Critical patent/DE69530408T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69530408T 1994-09-22 1995-09-21 Neue zwischenprodukte und verfahren zur herstellung von pyridin-derivaten Expired - Lifetime DE69530408T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25272694A JP3219946B2 (ja) 1994-09-22 1994-09-22 新規製造中間体及びピリジン誘導体の製造方法
PCT/JP1995/001911 WO1996009300A1 (fr) 1994-09-22 1995-09-21 Nouvel intermediaire pour la production d'un derive de pyridine et procede pour produire ce derive

Publications (2)

Publication Number Publication Date
DE69530408D1 true DE69530408D1 (de) 2003-05-22
DE69530408T2 DE69530408T2 (de) 2003-10-30

Family

ID=17241414

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69530408T Expired - Lifetime DE69530408T2 (de) 1994-09-22 1995-09-21 Neue zwischenprodukte und verfahren zur herstellung von pyridin-derivaten

Country Status (7)

Country Link
US (1) US5734059A (de)
EP (1) EP0787724B1 (de)
JP (1) JP3219946B2 (de)
CA (1) CA2200604C (de)
DE (1) DE69530408T2 (de)
ES (1) ES2196078T3 (de)
WO (1) WO1996009300A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1531820A1 (de) * 2002-08-30 2005-05-25 Memory Pharmaceuticals Corporation Anabasein-derivate zur behandlung von neurodegenerativen erkrankungen
US20050288333A1 (en) * 2004-06-08 2005-12-29 Kem William R Controlling angiogenesis with anabaseine analogs
US11096932B2 (en) 2016-09-29 2021-08-24 The Uab Research Foundation Methods and compositions for increasing mucus clearance
BR112020012457A2 (pt) * 2017-12-22 2020-11-24 Siegfried Ag preparação de nicotina racêmica por reação de nicotinato de etila com n-vinilpirrolidona na presença de uma base de alcoolato e subsequentes etapas de processo
WO2020099490A1 (en) 2018-11-14 2020-05-22 Novozymes A/S Oral care composition comprising enzymes
JP2023539234A (ja) 2020-08-24 2023-09-13 ノボザイムス アクティーゼルスカブ フルクタナーゼを含む口腔ケア組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2153357T3 (es) * 1991-03-01 2001-03-01 Univ Florida Uso de analogos nicotinicos para el tratamiento de enfermedades degenerativas del sistema nervioso.

Also Published As

Publication number Publication date
JP3219946B2 (ja) 2001-10-15
ES2196078T3 (es) 2003-12-16
WO1996009300A1 (fr) 1996-03-28
EP0787724B1 (de) 2003-04-16
CA2200604C (en) 2001-04-10
US5734059A (en) 1998-03-31
DE69530408T2 (de) 2003-10-30
CA2200604A1 (en) 1996-03-28
EP0787724A4 (de) 1998-01-07
EP0787724A1 (de) 1997-08-06
JPH0892242A (ja) 1996-04-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition