DE69528867D1 - Verbindungen und Verfahren zur Inhibierung der Verbreitung der HIV - Google Patents

Verbindungen und Verfahren zur Inhibierung der Verbreitung der HIV

Info

Publication number
DE69528867D1
DE69528867D1 DE69528867T DE69528867T DE69528867D1 DE 69528867 D1 DE69528867 D1 DE 69528867D1 DE 69528867 T DE69528867 T DE 69528867T DE 69528867 T DE69528867 T DE 69528867T DE 69528867 D1 DE69528867 D1 DE 69528867D1
Authority
DE
Germany
Prior art keywords
hiv
inhibiting
spread
compounds
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69528867T
Other languages
English (en)
Inventor
Thomas B Ryder
Theodore J Kwoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gen Probe Inc
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of DE69528867D1 publication Critical patent/DE69528867D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • C12N15/1132—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses against retroviridae, e.g. HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
DE69528867T 1994-07-19 1995-07-19 Verbindungen und Verfahren zur Inhibierung der Verbreitung der HIV Expired - Lifetime DE69528867D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/277,857 US5733781A (en) 1994-07-19 1994-07-19 Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus

Publications (1)

Publication Number Publication Date
DE69528867D1 true DE69528867D1 (de) 2003-01-02

Family

ID=23062654

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69528867T Expired - Lifetime DE69528867D1 (de) 1994-07-19 1995-07-19 Verbindungen und Verfahren zur Inhibierung der Verbreitung der HIV

Country Status (9)

Country Link
US (1) US5733781A (de)
EP (1) EP0697414B1 (de)
JP (1) JP3307944B2 (de)
KR (1) KR970704768A (de)
AT (1) ATE228142T1 (de)
AU (1) AU699233B2 (de)
CA (1) CA2194398A1 (de)
DE (1) DE69528867D1 (de)
WO (1) WO1996002557A1 (de)

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CA2279669A1 (en) * 1995-12-15 1997-06-16 Enzo Therapeutics, Inc. Property effecting and/or property exhibiting constructs for the expression of non-native nucleic acid processing components for therapeutic and diagnostic uses
US6776986B1 (en) 1996-06-06 2004-08-17 Novartis Ag Inhibition of HIV-1 replication by antisense RNA expression
DE69727984T2 (de) * 1996-07-09 2005-01-05 Canji, Inc., San Diego Verfahren zur messung viraler infektivität
US5962665A (en) * 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US7244570B2 (en) * 1998-08-04 2007-07-17 Luminex Molecular Diagnostics, Inc. Methods and compositions for modulating “marginally indiscriminant” hybridizations
US6867037B1 (en) * 1998-08-10 2005-03-15 Meiji Dairies Corp. High level secretory expression system of intact MK family protein
DE19850186A1 (de) * 1998-10-30 2000-05-25 Roche Diagnostics Gmbh Neue Primer und Sonden zum Nachweis von HIV
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
WO2000046403A2 (en) * 1999-02-03 2000-08-10 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OFHEALT H AND HUMAN SERVICES Methods and reagents for molecular detection of hiv-1 groups m, n and o
KR20020069627A (ko) * 2001-02-27 2002-09-05 동부한농화학 주식회사 육환의 아자슈거를 가진 뉴클레오타이드 유도체를 포함한포스포로티오에이트 올리고뉴클레오타이드 및 이들의에이즈 치료제로서의 새로운 용도
CA2452015C (en) 2001-07-05 2012-07-03 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
US6852491B2 (en) * 2001-09-04 2005-02-08 Abbott Laboratories Amplification and detection reagents for HIV-1
US20050222068A1 (en) * 2003-10-23 2005-10-06 Mourich Dan V Method and antisense composition for selective inhibition of HIV infection in hematopoietic cells
US20060205070A1 (en) * 2004-01-13 2006-09-14 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services HIV TEV compositions and methods of use
US20060240032A1 (en) * 2005-03-31 2006-10-26 Hinrichs David J Immunomodulating compositions and methods for use in the treatment of human autoimmune diseases
EP2121984A2 (de) * 2007-03-16 2009-11-25 454 Life Sciences Corporation System und verfahren zur erkennung von hiv-arzneiresistenten varianten
CA2746508A1 (en) * 2008-12-17 2010-07-15 Avi Biopharma, Inc. Antisense compositions and methods for modulating contact hypersensitivity or contact dermatitis
NL2010579C2 (nl) 2013-04-05 2014-10-07 Thomas Regout Internat B V Anti-kantelsamenstel voor een reeks van laden in een gereedschapskast.

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US5023243A (en) * 1981-10-23 1991-06-11 Molecular Biosystems, Inc. Oligonucleotide therapeutic agent and method of making same
GB8423659D0 (en) * 1984-09-19 1984-10-24 Pasteur Institut Cloned dna sequences
NZ209840A (en) * 1983-10-17 1988-11-29 Kaji Akira A method of inhibiting viral propagation by hybridising dna with the viral rna thus blocking its action
US4738922A (en) * 1984-05-25 1988-04-19 Dana Farber Cancer Institute Trans-acting transcriptional factors
IL79391A (en) * 1985-08-14 1994-06-24 Hughes Aircraft Co Non-spherical patch with a stepped key and a display system that uses it
US4752565A (en) 1986-04-07 1988-06-21 The United States Of America As Represented By The Department Of Health And Human Services Cell line producing AIDS viral antigens without producing infectious virus particles
US4806463A (en) * 1986-05-23 1989-02-21 Worcester Foundation For Experimental Biology Inhibition of HTLV-III by exogenous oligonucleotides
US5264423A (en) * 1987-03-25 1993-11-23 The United States Of America As Represented By The Department Of Health And Human Services Inhibitors for replication of retroviruses and for the expression of oncogene products
JP2758184B2 (ja) * 1987-06-22 1998-05-28 メデバ ホールディングス ベスローテン ベノートスハップ 肝炎ｂ表面抗原ワクチン
US5110802A (en) * 1987-07-14 1992-05-05 City Of Hope Oligonucleotide phosphonates and method of inhibiting a human immunodeficiency virus in vitro utilizing said oligonucleotide phosphonates
KR960002561B1 (ko) 1987-09-21 1996-02-22 젠-프로우브 인코퍼레이티드 균질보호분석법
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US5449769A (en) 1989-03-06 1995-09-12 Gen-Probe Incorporated Method and reagent for sulfurization of organophosphorous compounds
ES2262166T3 (es) * 1989-06-02 2006-11-16 Institut Pasteur Sintesis de proteinas o polipeptidos codificados por un secuencia nucleotidica vih-1, vih-2 o siv.
US5144019A (en) * 1989-06-21 1992-09-01 City Of Hope Ribozyme cleavage of HIV-I RNA
WO1991010746A1 (en) * 1990-01-10 1991-07-25 Chiron Corporation Dna-dependent rna polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
US5166195A (en) * 1990-05-11 1992-11-24 Isis Pharmaceuticals, Inc. Antisense inhibitors of the human immunodeficiency virus phosphorothioate oligonucleotides
DE69130331T2 (de) 1990-10-26 1999-03-04 Genta Inc Verbessertes verfahren zur synthese von oligomeren
AU1741692A (en) * 1991-03-13 1992-10-21 Regents Of The University Of California, The Detection of 3'-azido-3'-deoxythymidine resistance
FR2677039B1 (fr) * 1991-05-31 1994-09-09 Cis Bio Int Oligonucleotides, utilisables comme reactifs pour la detection in vitro des infections a retrovirus de type hiv et procede de detection de retrovirus de type hiv.
US5226326A (en) * 1991-05-31 1993-07-13 Environmental Stress Screening Corp. Vibration chamber
PT726962E (pt) * 1991-12-23 2006-10-31 Chiron Corp Sondas para hiv para uso em ensaios de hibridacao em sanduiche em fase de solucao
US5585479A (en) * 1992-07-24 1996-12-17 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ELAM-I RNA
JPH08504570A (ja) * 1992-10-05 1996-05-21 ハイブライドン インコーポレイテッド 治療用抗ｈｉｖオリゴヌクレオチドと薬剤
CA2159103C (en) * 1993-03-26 2002-03-12 Sherrol H. Mcdonough Detection of human immunodeficiency virus type 1
US8328553B2 (en) 2006-03-09 2012-12-11 3M Innovative Properties Company Device for dispensing material
CN101689633A (zh) 2007-05-08 2010-03-31 加利福尼亚大学董事会 高放电倍率锂离子电池
US8803361B2 (en) 2011-01-19 2014-08-12 Schneider Electric It Corporation Apparatus and method for providing uninterruptible power
US9202037B2 (en) 2012-06-08 2015-12-01 General Electric Company System and method for using machine readable code to commission device applications

Also Published As

Publication number Publication date
AU699233B2 (en) 1998-11-26
CA2194398A1 (en) 1996-02-01
WO1996002557A1 (en) 1996-02-01
JP3307944B2 (ja) 2002-07-29
KR970704768A (ko) 1997-09-06
ATE228142T1 (de) 2002-12-15
AU3135495A (en) 1996-02-16
US5733781A (en) 1998-03-31
EP0697414A1 (de) 1996-02-21
EP0697414B1 (de) 2002-11-20
JPH10501421A (ja) 1998-02-10

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Legal Events

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8332 No legal effect for de