DE69528291D1 - Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung - Google Patents
Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellungInfo
- Publication number
- DE69528291D1 DE69528291D1 DE69528291T DE69528291T DE69528291D1 DE 69528291 D1 DE69528291 D1 DE 69528291D1 DE 69528291 T DE69528291 T DE 69528291T DE 69528291 T DE69528291 T DE 69528291T DE 69528291 D1 DE69528291 D1 DE 69528291D1
- Authority
- DE
- Germany
- Prior art keywords
- sub
- beta
- production
- fatty acid
- therapeutically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 2
- 229930195729 fatty acid Natural products 0.000 title abstract 2
- 239000000194 fatty acid Substances 0.000 title abstract 2
- 150000004665 fatty acids Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 230000005907 cancer growth Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO952796A NO952796D0 (no) | 1995-07-14 | 1995-07-14 | Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater |
PCT/NO1995/000195 WO1997003663A1 (en) | 1995-07-14 | 1995-10-25 | NON-β-OXIDIZABLE FATTY ACID ANALOGUES, THEIR USES AS THERAPEUTIC ACTIVE MEDICAMENTS, AND PREPARATION THEREOF |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69528291D1 true DE69528291D1 (de) | 2002-10-24 |
DE69528291T2 DE69528291T2 (de) | 2003-05-08 |
Family
ID=19898394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69528291T Expired - Fee Related DE69528291T2 (de) | 1995-07-14 | 1995-10-25 | Nicht-beta oxidierbare fettsäureanaloge,deren verwendung als therapeutisch wirksame medikamente sowie deren herstellung |
Country Status (13)
Country | Link |
---|---|
US (1) | US6046237A (de) |
EP (3) | EP0840604B1 (de) |
JP (1) | JP3553966B2 (de) |
KR (1) | KR100394986B1 (de) |
AT (1) | ATE224188T1 (de) |
AU (2) | AU4272696A (de) |
CA (1) | CA2226871A1 (de) |
DE (1) | DE69528291T2 (de) |
DK (1) | DK0840604T3 (de) |
ES (1) | ES2183889T3 (de) |
NO (1) | NO952796D0 (de) |
PT (1) | PT840604E (de) |
WO (1) | WO1997003663A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7240398A (en) * | 1998-05-08 | 1999-11-29 | Rolf Berge | Use of non-beta-oxidizable fatty acid analogues for treatment of syndrome-x conditions |
AUPQ291499A0 (en) * | 1999-09-17 | 1999-10-07 | Women's And Children's Hospital Adelaide | Novel nitro and sulphur containing compounds |
AU784116B2 (en) * | 1999-09-17 | 2006-02-09 | Peplin Biolipids Pty Ltd | Anti-cancer nitro- and thia-fatty acids |
NO328803B1 (no) * | 2000-03-03 | 2010-05-18 | Thia Medica | Nye fettsyreanaloger |
NO20003591L (no) * | 2000-07-13 | 2002-01-14 | Thia Medica As | Fettsyreanaloger for behandling av kreft |
NO20006008L (no) * | 2000-11-28 | 2002-05-29 | Thia Medica As | Fettsyreanaloger for behandling av inflammatoriske og autoimmune sykdommer |
US7842727B2 (en) * | 2001-03-27 | 2010-11-30 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US6495719B2 (en) | 2001-03-27 | 2002-12-17 | Circagen Pharmaceutical | Histone deacetylase inhibitors |
US7312247B2 (en) | 2001-03-27 | 2007-12-25 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
US8026280B2 (en) | 2001-03-27 | 2011-09-27 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
FR2828487B1 (fr) | 2001-08-09 | 2005-05-27 | Genfit S A | Nouveaux composes derives d'acides gras, preparation et utilisations |
AU2003243272A1 (en) * | 2002-05-22 | 2003-12-12 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors based on alpha-ketoepoxide compounds |
EP1515978A1 (de) | 2002-06-20 | 2005-03-23 | IC Vec Limited | Schwefelhaltige phospholipidderivate |
CA2506504A1 (en) * | 2002-11-20 | 2004-06-03 | Errant Gene Therapeutics, Llc | Treatment of lung cells with histone deacetylase inhibitors |
FR2850650B1 (fr) * | 2003-01-31 | 2005-03-25 | Genfit S A | Utilisation therapeutique d'acylglycerols et de leurs analogues azotes et sulfures |
FR2850869B1 (fr) * | 2003-02-12 | 2005-03-25 | Genfit S A | Utilisations d'aminopropanediols acyles et de leurs analogues azotes et sulfures |
US20090215895A1 (en) * | 2004-01-30 | 2009-08-27 | Peplin Biolipids Pty Ltd | Therapeutic and carrier molecules |
EP2275140B1 (de) * | 2004-07-19 | 2017-11-01 | Bergen Teknologioverforing AS | Zusammensetzung enthaltend Pflanzen- oder Fischöl und nicht-oxidierbaren Fettsäuren-enthaltenden Komponenten |
CA2587013A1 (en) * | 2004-11-08 | 2006-05-18 | Errant Gene Therapeutics, Llc | Histone deacetylase inhibitors |
WO2014140934A2 (en) | 2013-03-11 | 2014-09-18 | Life Science Nutrition As | Natural lipids containing non-oxidizable fatty acids |
CA2904898C (en) | 2013-03-11 | 2019-10-15 | Jan Remmereit | Lipid compositions containing bioactive fatty acids |
CN105498622B (zh) * | 2015-12-10 | 2017-10-17 | 江南大学 | 一种含硒表面活性剂及其制备方法和应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2208533A1 (de) * | 1972-02-23 | 1973-09-27 | Kolmar Laboratories | Neue alkylthioaether |
GB8813012D0 (en) * | 1988-06-02 | 1988-07-06 | Norsk Hydro As | Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals |
-
1995
- 1995-07-14 NO NO952796A patent/NO952796D0/no unknown
- 1995-10-25 DE DE69528291T patent/DE69528291T2/de not_active Expired - Fee Related
- 1995-10-25 ES ES95941241T patent/ES2183889T3/es not_active Expired - Lifetime
- 1995-10-25 EP EP95941241A patent/EP0840604B1/de not_active Expired - Lifetime
- 1995-10-25 CA CA002226871A patent/CA2226871A1/en not_active Abandoned
- 1995-10-25 AT AT95941241T patent/ATE224188T1/de not_active IP Right Cessation
- 1995-10-25 KR KR19980700295A patent/KR100394986B1/ko not_active IP Right Cessation
- 1995-10-25 DK DK95941241T patent/DK0840604T3/da active
- 1995-10-25 EP EP02075955A patent/EP1232750A1/de not_active Withdrawn
- 1995-10-25 PT PT95941241T patent/PT840604E/pt unknown
- 1995-10-25 JP JP50656797A patent/JP3553966B2/ja not_active Expired - Fee Related
- 1995-10-25 WO PCT/NO1995/000195 patent/WO1997003663A1/en active IP Right Grant
- 1995-10-25 EP EP02075954A patent/EP1232749A1/de not_active Ceased
- 1995-10-25 AU AU42726/96A patent/AU4272696A/en not_active Abandoned
- 1995-10-25 US US08/981,956 patent/US6046237A/en not_active Expired - Lifetime
-
2000
- 2000-09-21 AU AU61243/00A patent/AU734431B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DE69528291T2 (de) | 2003-05-08 |
PT840604E (pt) | 2003-01-31 |
CA2226871A1 (en) | 1997-02-06 |
AU4272696A (en) | 1997-02-18 |
AU6124300A (en) | 2000-11-30 |
DK0840604T3 (da) | 2002-12-30 |
EP1232749A1 (de) | 2002-08-21 |
WO1997003663A1 (en) | 1997-02-06 |
KR19990028993A (ko) | 1999-04-15 |
EP0840604A1 (de) | 1998-05-13 |
EP0840604B1 (de) | 2002-09-18 |
KR100394986B1 (ko) | 2004-01-24 |
ATE224188T1 (de) | 2002-10-15 |
JPH11514339A (ja) | 1999-12-07 |
US6046237A (en) | 2000-04-04 |
NO952796D0 (no) | 1995-07-14 |
JP3553966B2 (ja) | 2004-08-11 |
AU734431B2 (en) | 2001-06-14 |
EP1232750A1 (de) | 2002-08-21 |
ES2183889T3 (es) | 2003-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |