DE69525859T2 - Neue tricyclische kondensierte heterocyclische verbindungen als antioxidantien - Google Patents

Neue tricyclische kondensierte heterocyclische verbindungen als antioxidantien

Info

Publication number
DE69525859T2
DE69525859T2 DE69525859T DE69525859T DE69525859T2 DE 69525859 T2 DE69525859 T2 DE 69525859T2 DE 69525859 T DE69525859 T DE 69525859T DE 69525859 T DE69525859 T DE 69525859T DE 69525859 T2 DE69525859 T2 DE 69525859T2
Authority
DE
Germany
Prior art keywords
group
condensed heterocyclic
oxidative
compound
promising
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69525859T
Other languages
English (en)
Other versions
DE69525859D1 (de
Inventor
Shuji Jinno
Yasuyo Kogure
Hiroyuki Onuki
Takaaki Okita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissui Corp
Original Assignee
Nippon Suisan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Suisan Kaisha Ltd filed Critical Nippon Suisan Kaisha Ltd
Publication of DE69525859D1 publication Critical patent/DE69525859D1/de
Application granted granted Critical
Publication of DE69525859T2 publication Critical patent/DE69525859T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
DE69525859T 1994-09-28 1995-09-28 Neue tricyclische kondensierte heterocyclische verbindungen als antioxidantien Expired - Lifetime DE69525859T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP25878194 1994-09-28
JP3317895 1995-01-30
PCT/JP1995/001975 WO1996010021A1 (fr) 1994-09-28 1995-09-28 Compose antioxydant heterocyclique a trois cycles fusionnes

Publications (2)

Publication Number Publication Date
DE69525859D1 DE69525859D1 (de) 2002-04-18
DE69525859T2 true DE69525859T2 (de) 2002-10-24

Family

ID=26371823

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69525859T Expired - Lifetime DE69525859T2 (de) 1994-09-28 1995-09-28 Neue tricyclische kondensierte heterocyclische verbindungen als antioxidantien

Country Status (10)

Country Link
US (1) US5734067A (de)
EP (1) EP0805155B1 (de)
JP (1) JP3328673B2 (de)
AT (1) ATE214386T1 (de)
CA (1) CA2200598C (de)
DE (1) DE69525859T2 (de)
DK (1) DK0805155T3 (de)
ES (1) ES2173968T3 (de)
PT (1) PT805155E (de)
WO (1) WO1996010021A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR19990081834A (ko) * 1996-01-19 1999-11-15 미노다 가츠스케 기관 평활근 이완제
JP3471778B2 (ja) * 1999-06-03 2003-12-02 日本水産株式会社 三環性縮合複素環化合物、その製造方法および用途
IL147593A0 (en) 1999-07-19 2002-08-14 Sankyo Co Pharmaceutical compositions containing fused hetrocyclic compounds
JP2007230866A (ja) * 2004-02-20 2007-09-13 Nippon Suisan Kaisha Ltd 高尿酸血症治療剤
JP2010516679A (ja) * 2007-01-19 2010-05-20 マリンクロット インコーポレイテッド 診断用および治療用シクロオキシゲナーゼ−２結合リガンド

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029587B1 (de) * 1979-11-27 1984-06-13 Merck Sharp & Dohme (I.A.) Corp. 3-Hydroxymethyldibenzo (b,f)thiepine und Dibenzo(b,f)thiepin-3-carboxaldehyde als Prostaglandin-Antagonisten, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen
JPS56166180A (en) * 1980-05-28 1981-12-21 Chugai Pharmaceut Co Ltd Dibenzoxazepine derivative and its preparation
JPH05153990A (ja) * 1991-12-06 1993-06-22 Nippon Suisan Kaisha Ltd 新規ジベンゾオキセピン誘導体

Also Published As

Publication number Publication date
ES2173968T3 (es) 2002-11-01
US5734067A (en) 1998-03-31
EP0805155A4 (de) 1998-01-07
DE69525859D1 (de) 2002-04-18
CA2200598C (en) 1999-12-07
WO1996010021A1 (fr) 1996-04-04
EP0805155B1 (de) 2002-03-13
DK0805155T3 (da) 2002-07-08
PT805155E (pt) 2002-09-30
EP0805155A1 (de) 1997-11-05
CA2200598A1 (en) 1996-04-04
JP3328673B2 (ja) 2002-09-30
ATE214386T1 (de) 2002-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: FIENER, J., PAT.-ANW., 87719 MINDELHEIM

8330 Complete renunciation