DE69523585D1 - Wundheilmittel - Google Patents

Wundheilmittel

Info

Publication number
DE69523585D1
DE69523585D1 DE69523585T DE69523585T DE69523585D1 DE 69523585 D1 DE69523585 D1 DE 69523585D1 DE 69523585 T DE69523585 T DE 69523585T DE 69523585 T DE69523585 T DE 69523585T DE 69523585 D1 DE69523585 D1 DE 69523585D1
Authority
DE
Germany
Prior art keywords
pct
chitosan
polysaccharide
composition
heparin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69523585T
Other languages
English (en)
Other versions
DE69523585T2 (de
Inventor
Ibrahim Gouda
Olle Larm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicarb AB
Original Assignee
Medicarb AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicarb AB filed Critical Medicarb AB
Publication of DE69523585D1 publication Critical patent/DE69523585D1/de
Application granted granted Critical
Publication of DE69523585T2 publication Critical patent/DE69523585T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69523585T 1994-07-19 1995-07-18 Wundheilmittel Expired - Lifetime DE69523585T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9402531A SE9402531L (sv) 1994-07-19 1994-07-19 Sårläkningsmedel
PCT/SE1995/000875 WO1996002260A1 (en) 1994-07-19 1995-07-18 Wound healing agent

Publications (2)

Publication Number Publication Date
DE69523585D1 true DE69523585D1 (de) 2001-12-06
DE69523585T2 DE69523585T2 (de) 2002-04-11

Family

ID=20394771

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69523585T Expired - Lifetime DE69523585T2 (de) 1994-07-19 1995-07-18 Wundheilmittel

Country Status (11)

Country Link
US (1) US5902798A (de)
EP (1) EP0759760B1 (de)
JP (1) JP3337472B2 (de)
AT (1) ATE207753T1 (de)
AU (1) AU691322B2 (de)
CA (1) CA2194976C (de)
DE (1) DE69523585T2 (de)
DK (1) DK0759760T3 (de)
ES (1) ES2161903T3 (de)
SE (1) SE9402531L (de)
WO (1) WO1996002260A1 (de)

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SE508760C2 (sv) * 1997-04-29 1998-11-02 Medicarb Ab Användning av en komposition innefattande kitosan i kombination med en polysackarid, som aktiv komponent i ett lösningsmedel, för framställning av ett spendoppningsmedel för mjölkproducerande djur
NL1011680C2 (nl) 1999-03-26 2000-09-27 Nutricia Nv Voedingssamenstellen die licht negatief geladen, niet-verteerbare polysacchariden bevatten en gebruik ervan voor het verminderen van transport door tight junctions.
US6391334B1 (en) 1999-10-25 2002-05-21 Amway Corporation Barrier-forming composition
EP1229940B1 (de) * 1999-11-15 2014-05-14 Piramal Healthcare (Canada) Limited Temperaturgesteuerte und ph-abhängige selbstgelierende biopolymere wässrige lösung
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
ATE243049T1 (de) * 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
GB9929472D0 (en) * 1999-12-13 2000-02-09 Btg Int Ltd Polymeric film
DK1294414T3 (da) * 2000-06-29 2006-07-24 Biosyntech Canada Inc Præparat og fremgangsmåde til heling og regenerering af brusk og andre væv
DE60125973D1 (de) * 2000-11-15 2007-02-22 Biosyntech Canada Inc Verfahren zur wiederherstellung einer geschädigten bandscheibe
US6623761B2 (en) 2000-12-22 2003-09-23 Hassan Emadeldin M. Method of making nanoparticles of substantially water insoluble materials
KR20020066024A (ko) * 2001-02-08 2002-08-14 굿젠 주식회사 수용성 키토산과 헤파린으로 이루어진 상처 치유 촉진연고 조성물과 필름 및 제품
SE522529C2 (sv) 2001-04-12 2004-02-17 Medicarb Ab Effervescent fastämneskomposition innefattande som aktiv komponent kitosan, dess derivat och salter därav, användning samt framställning därav
EP1385482A1 (de) * 2001-04-12 2004-02-04 Medicarb AB Sprudelnde feste stoffzusammensetzung
US7297343B2 (en) * 2001-07-31 2007-11-20 Biosurface Engineering Technologies, Inc. Bioactive medical films
KR20020060627A (ko) * 2002-01-16 2002-07-18 조석형 키토산/음이온성 다당류의 창상 치유제
WO2003070749A2 (en) 2002-02-15 2003-08-28 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
DE60334224D1 (de) * 2002-07-16 2010-10-28 Biosyntech Canada Inc Zusammensetzung für die herstellung zellkompatibler, injizierbarer, selbstgelierender chitosan lösungen zum einkapseln und verabreichen von lebenden zellen oderbiologisch aktiven faktoren
US7554021B2 (en) 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
US20070053848A1 (en) * 2003-08-26 2007-03-08 Stockel Richard F Antimicrobial materials for dental care applications
JP2006347883A (ja) * 2003-09-08 2006-12-28 Neetec:Kk 糖鎖含有キトサン誘導体及びグリコサミノグリカンを含有する医療用組成物
AU2004296181A1 (en) 2003-12-05 2005-06-23 Northwestern University Self-assembling peptide amphiphiles and related methods for growth factor delivery
US20050136024A1 (en) * 2003-12-22 2005-06-23 Stockel Richard F. Dermatological compositions
US20070086977A1 (en) * 2003-12-22 2007-04-19 Stockel Richard F Method of treating dermatological conditions
US20050283004A1 (en) * 2004-06-18 2005-12-22 Hopax Chemicals Manufacturing Co., Ltd. Alkylsulfonated polyaminosaccharides
WO2006096614A2 (en) * 2005-03-04 2006-09-14 Northwestern University Angiogenic heparin binding peptide amphiphiles
CA2628244A1 (en) * 2005-11-04 2007-05-10 Bio Syntech Canada Inc. Gel formation of polyelectrolyte aqueous solutions by thermally induced changes in ionization state
DE102006020035A1 (de) * 2006-04-26 2007-10-31 B. Braun Melsungen Ag Herstellung und Verwendung von Poly(hydroxyethylstärke)chitin- und Poly(Carboxymethylstärke)chitin-Verbindungen
EP1958613A1 (de) * 2007-02-15 2008-08-20 Polichem S.A. Dermale filmbildende flüssige Formulierungen zur Wirkstofffreisetzung auf der Haut
US8076295B2 (en) 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
CN101848739A (zh) 2007-08-28 2010-09-29 T·阿萨纳夏季斯 手术用水凝胶
ES2650937T3 (es) * 2008-11-20 2018-01-23 Laboratori Derivati Organici S.P.A. Composiciones dermatológicas que comprenden sulfato de heparano
ES2575685T3 (es) * 2008-12-06 2016-06-30 B. Braun Melsungen Ag Compuestos que consisten en un glucosaminoglucano y un almidón para el transporte de medicamentos o marcadores fluorescentes covalentemente unidos
CN102365099A (zh) * 2009-03-31 2012-02-29 B·布朗·梅尔松根有限公司 胺化多糖粘合制品
JP2012523463A (ja) 2009-04-13 2012-10-04 ノースウエスタン ユニバーシティ 軟骨再生のための新規なペプチドベースの足場およびその使用方法
US8906883B2 (en) * 2009-06-10 2014-12-09 Exthera Ab Treatment of oral mucositis by administering an ionic complex of chitosan and a negatively charged polysaccharide selected from heparin, heparan sulfate and dextran sulfate
JP5752123B2 (ja) 2009-09-01 2015-07-22 メドヴェント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング キトサン組織被覆材
US9629856B2 (en) 2010-03-03 2017-04-25 Anteis Sa Compositions and methods for the treatment of skin diseases and disorders using antimicrobial peptide sequestering compounds
CN105451745B (zh) 2013-08-13 2018-03-27 生化学工业株式会社 含有阳离子化壳聚糖的药物
US9192574B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan paste wound dressing
US9192692B2 (en) 2013-10-24 2015-11-24 Medtronic Xomed, Inc. Chitosan stenting paste
FR3016882A1 (fr) 2014-01-30 2015-07-31 Sofradim Production Procede de preparation de chitosane a haut degre d’acetylation
US10126298B2 (en) 2015-05-04 2018-11-13 Arman Nabatian Hydrogels containing embedded substrates for targeted binding of molecules
US9248160B1 (en) * 2015-07-28 2016-02-02 Zo Skin Health, Inc. Post-procedure skin care systems, compositions, and methods of use thereof
CN111587129A (zh) * 2018-01-12 2020-08-25 波士顿科学国际有限公司 实现止血的粉末
EP3787593A1 (de) 2018-05-04 2021-03-10 Bonoss Medical Aktiebolag Zusammensetzung zur verminderung der narbenbildung

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US4378017A (en) * 1980-03-21 1983-03-29 Kureha Kagaku Kogyo Kabushiki Kaisha Composite material of de-N-acetylated chitin and fibrous collagen
US4326532A (en) * 1980-10-06 1982-04-27 Minnesota Mining And Manufacturing Company Antithrombogenic articles
US4532134A (en) * 1981-04-06 1985-07-30 Malette William Graham Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
CA1202904A (en) * 1983-11-21 1986-04-08 Brian G. Sparkes Chitosan based wound dressing materials
JPS61253065A (ja) * 1985-05-02 1986-11-10 片倉チツカリン株式会社 キトサン誘導体およびコラ−ゲンの複合材の医用材料およびその製造法
US5037810A (en) * 1987-03-17 1991-08-06 Saliba Jr Michael J Medical application for heparin and related molecules
US4879282A (en) * 1987-03-17 1989-11-07 Saliba Jr Michael J Medical application for heparin and related molecules
DE4200080A1 (de) * 1992-01-03 1993-09-30 Reinmueller Johannes Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung
JP3205104B2 (ja) * 1992-01-20 2001-09-04 川研ファインケミカル株式会社 化粧料
SE9402529D0 (sv) * 1994-07-19 1994-07-19 Astra Ab Anti-adherensmedel

Also Published As

Publication number Publication date
US5902798A (en) 1999-05-11
SE9402531D0 (sv) 1994-07-19
AU3090295A (en) 1996-02-16
CA2194976A1 (en) 1996-02-01
SE9402531L (sv) 1996-01-20
JPH10502665A (ja) 1998-03-10
ES2161903T3 (es) 2001-12-16
JP3337472B2 (ja) 2002-10-21
DE69523585T2 (de) 2002-04-11
EP0759760A1 (de) 1997-03-05
DK0759760T3 (da) 2001-11-26
ATE207753T1 (de) 2001-11-15
EP0759760B1 (de) 2001-10-31
WO1996002260A1 (en) 1996-02-01
AU691322B2 (en) 1998-05-14
CA2194976C (en) 2002-04-30

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Legal Events

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8364 No opposition during term of opposition