DE69521810D1 - Dreikernige kationische platinkomplexe mit antitumor wirkung, und diese enthaltende arzneizusammensetzungen - Google Patents

Dreikernige kationische platinkomplexe mit antitumor wirkung, und diese enthaltende arzneizusammensetzungen

Info

Publication number
DE69521810D1
DE69521810D1 DE69521810T DE69521810T DE69521810D1 DE 69521810 D1 DE69521810 D1 DE 69521810D1 DE 69521810 T DE69521810 T DE 69521810T DE 69521810 T DE69521810 T DE 69521810T DE 69521810 D1 DE69521810 D1 DE 69521810D1
Authority
DE
Germany
Prior art keywords
compositions containing
pct
trinicular
platinum complexes
antitumor effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69521810T
Other languages
English (en)
Other versions
DE69521810T2 (de
Inventor
Mariella Valsecchi
Paolo Pavesi
Carlo Bugatti
Ernesto Menta
C Giuliani
Carla Manzotti
Silvano Spinelli
Nicholas Farrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE69521810D1 publication Critical patent/DE69521810D1/de
Publication of DE69521810T2 publication Critical patent/DE69521810T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69521810T 1994-11-24 1995-11-13 Dreikernige kationische platinkomplexe mit antitumor wirkung, und diese enthaltende arzneizusammensetzungen Expired - Fee Related DE69521810T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI942383A IT1271089B (it) 1994-11-24 1994-11-24 Platino complessi cationici trinucleari ad attivita' antitumorale
PCT/EP1995/004455 WO1996016068A1 (en) 1994-11-24 1995-11-13 Trinuclear cationic platinum complexes having antitumour activity and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69521810D1 true DE69521810D1 (de) 2001-08-23
DE69521810T2 DE69521810T2 (de) 2002-04-04

Family

ID=11369905

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521810T Expired - Fee Related DE69521810T2 (de) 1994-11-24 1995-11-13 Dreikernige kationische platinkomplexe mit antitumor wirkung, und diese enthaltende arzneizusammensetzungen

Country Status (14)

Country Link
US (1) US6011166A (de)
EP (1) EP0793667B1 (de)
JP (1) JPH10509159A (de)
AT (1) ATE203244T1 (de)
AU (1) AU3928695A (de)
CA (1) CA2205868C (de)
DE (1) DE69521810T2 (de)
DK (1) DK0793667T3 (de)
ES (1) ES2161913T3 (de)
GR (1) GR3036926T3 (de)
IT (1) IT1271089B (de)
PT (1) PT793667E (de)
WO (1) WO1996016068A1 (de)
ZA (1) ZA959986B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1292481B1 (it) * 1997-07-04 1999-02-08 Boehringer Mannheim Italia Platino complessi cationici tetra- e penta-nucleari ad attivita' antitumorale
WO2004006859A2 (en) * 2002-07-16 2004-01-22 Sonus Pharmaceuticals, Inc. Platinum compound
US7138520B2 (en) * 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
US6963002B2 (en) 2003-07-04 2005-11-08 Glenmark Pharmaceuticals Limited Process for the preparation of 4,4-dimethyl-6-ethynylthiochroman
WO2005090372A2 (en) * 2004-03-15 2005-09-29 Sonus Pharmaceuticals, Inc. Platinum carboxylate anticancer compounds
US7611733B2 (en) * 2004-03-26 2009-11-03 Cell Therapeutics Europe S.R.L. Nanoparticle formulations of platinum compounds
EA017521B1 (ru) 2008-01-16 2013-01-30 Тенсиндо Фармасьютикал Ко., Лтд. Комплексное соединение платины и его применение
CN102516315B (zh) * 2011-12-12 2014-12-10 中山大学 一种具有y型结构的三核铂配合物及其对人胃腺癌细胞的靶向性

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380897A (en) * 1993-05-25 1995-01-10 Hoeschele; James D. Tri(platinum) complexes
IT1273391B (it) * 1994-03-31 1997-07-08 Boehringer Mannheim Italia Platino complessi cationici trinucleari ad attivita' antitumorale e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
DE69521810T2 (de) 2002-04-04
CA2205868A1 (en) 1996-05-30
JPH10509159A (ja) 1998-09-08
EP0793667A1 (de) 1997-09-10
GR3036926T3 (en) 2002-01-31
IT1271089B (it) 1997-05-26
ITMI942383A1 (it) 1996-05-24
DK0793667T3 (da) 2001-10-22
CA2205868C (en) 2007-03-20
ZA959986B (en) 1996-06-10
WO1996016068A1 (en) 1996-05-30
EP0793667B1 (de) 2001-07-18
ITMI942383A0 (it) 1994-11-24
AU3928695A (en) 1996-06-17
ATE203244T1 (de) 2001-08-15
PT793667E (pt) 2001-12-28
ES2161913T3 (es) 2001-12-16
US6011166A (en) 2000-01-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee