DE69510894D1 - Verfahren zur Herstellung mucoadhesiver Stärke - Google Patents

Verfahren zur Herstellung mucoadhesiver Stärke

Info

Publication number
DE69510894D1
DE69510894D1 DE69510894T DE69510894T DE69510894D1 DE 69510894 D1 DE69510894 D1 DE 69510894D1 DE 69510894 T DE69510894 T DE 69510894T DE 69510894 T DE69510894 T DE 69510894T DE 69510894 D1 DE69510894 D1 DE 69510894D1
Authority
DE
Germany
Prior art keywords
mucoadhesive
starch
production
mucoadhesive starch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69510894T
Other languages
English (en)
Other versions
DE69510894T2 (de
Inventor
Ponti Roberto De
Alessandro Martini
Lorena Muggetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia and Upjohn SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9412064A external-priority patent/GB9412064D0/en
Priority claimed from GBGB9501936.0A external-priority patent/GB9501936D0/en
Application filed by Pharmacia and Upjohn SpA filed Critical Pharmacia and Upjohn SpA
Publication of DE69510894D1 publication Critical patent/DE69510894D1/de
Application granted granted Critical
Publication of DE69510894T2 publication Critical patent/DE69510894T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J103/00—Adhesives based on starch, amylose or amylopectin or on their derivatives or degradation products
    • C09J103/02—Starch; Degradation products thereof, e.g. dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
DE69510894T 1994-06-16 1995-05-30 Verfahren zur Herstellung mucoadhesiver Stärke Expired - Fee Related DE69510894T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9412064A GB9412064D0 (en) 1994-06-16 1994-06-16 Bioadhesive starches and process for their preparation
GBGB9501936.0A GB9501936D0 (en) 1995-02-01 1995-02-01 Bioadhesive starches and process for thier preparation
PCT/EP1995/002044 WO1995034582A1 (en) 1994-06-16 1995-05-30 Bioadhesive starches and process for their preparation

Publications (2)

Publication Number Publication Date
DE69510894D1 true DE69510894D1 (de) 1999-08-26
DE69510894T2 DE69510894T2 (de) 2000-02-03

Family

ID=26305072

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69510894T Expired - Fee Related DE69510894T2 (de) 1994-06-16 1995-05-30 Verfahren zur Herstellung mucoadhesiver Stärke

Country Status (6)

Country Link
US (1) US5804209A (de)
EP (1) EP0714411B1 (de)
JP (1) JPH09503023A (de)
AU (1) AU692565B2 (de)
DE (1) DE69510894T2 (de)
WO (1) WO1995034582A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9605857D0 (en) * 1996-03-20 1996-05-22 Tester Richard F Polysaccharides as chemical release systems
DE19646392A1 (de) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US6248358B1 (en) 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6387403B1 (en) 1999-09-15 2002-05-14 Alza Corporation Dosage forms and methods for providing effective reboxetine therapy with once-a-day dosing
WO2003092649A2 (en) * 2002-04-29 2003-11-13 Alza Corporation Reduced formate poly(alkylene oxides) with secondary amines for reducing impurity formation
ES2212728B1 (es) * 2002-09-05 2005-10-16 Tecofarma, S.L. Sistema de retencion oral controlada de sustancias cationicas.
WO2004073729A1 (ja) * 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
EP1607117A4 (de) 2003-03-27 2007-10-24 Bioactis Ltd Applikator für pulvermedikation in der nasenhöhle
US20060013873A1 (en) * 2004-07-16 2006-01-19 Chih-Chiang Yang Bioadhesive dosage form of steroids
WO2006016530A1 (ja) * 2004-08-10 2006-02-16 Translational Research, Ltd. 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
SE530184C2 (sv) * 2005-12-23 2008-03-18 Kjell Stenberg Bioadhesiv farmaceutisk filmkomposition innehållande lågviskösa alginater
WO2008078730A1 (ja) 2006-12-26 2008-07-03 Translational Research, Ltd. 経鼻投与用製剤
US9101539B2 (en) * 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
WO2011013003A2 (en) * 2009-07-31 2011-02-03 Shin Nippon Biomedical Laboratories, Ltd. Intranasal granisetron and nasal applicator
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3025217A (en) * 1958-05-28 1962-03-13 Olin Mathieson Dry amylopectin therapeutic dusting powders
JPS61148114A (ja) * 1984-11-15 1986-07-05 Teijin Ltd ニフエジピンの顆粒剤
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
JPH01148114A (ja) * 1987-12-03 1989-06-09 Kubota Ltd 苗移植機
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
IT1241417B (it) * 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
US5284659A (en) * 1990-03-30 1994-02-08 Cherukuri Subraman R Encapsulated flavor with bioadhesive character in pressed mints and confections

Also Published As

Publication number Publication date
AU2786595A (en) 1996-01-05
JPH09503023A (ja) 1997-03-25
EP0714411A1 (de) 1996-06-05
EP0714411B1 (de) 1999-07-21
AU692565B2 (en) 1998-06-11
US5804209A (en) 1998-09-08
WO1995034582A1 (en) 1995-12-21
DE69510894T2 (de) 2000-02-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee