DE69432422D1 - Methoden zum aufspüren von anti-östrogenverbindungen - Google Patents
Methoden zum aufspüren von anti-östrogenverbindungenInfo
- Publication number
- DE69432422D1 DE69432422D1 DE69432422T DE69432422T DE69432422D1 DE 69432422 D1 DE69432422 D1 DE 69432422D1 DE 69432422 T DE69432422 T DE 69432422T DE 69432422 T DE69432422 T DE 69432422T DE 69432422 D1 DE69432422 D1 DE 69432422D1
- Authority
- DE
- Germany
- Prior art keywords
- compounds
- methods
- detecting anti
- reporter gene
- estrogen compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US115161 | 1987-10-30 | ||
US11516193A | 1993-09-01 | 1993-09-01 | |
PCT/US1994/009898 WO1995006754A1 (en) | 1993-09-01 | 1994-09-01 | Methods for screening antiestrogen compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69432422D1 true DE69432422D1 (de) | 2003-05-08 |
DE69432422T2 DE69432422T2 (de) | 2004-03-04 |
Family
ID=22359653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69432422T Expired - Fee Related DE69432422T2 (de) | 1993-09-01 | 1994-09-01 | Methoden zum aufspüren von anti-östrogenverbindungen |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0724648B1 (de) |
JP (1) | JP3503945B2 (de) |
KR (1) | KR100355647B1 (de) |
AT (1) | ATE236247T1 (de) |
AU (1) | AU682398B2 (de) |
CA (1) | CA2169466A1 (de) |
DE (1) | DE69432422T2 (de) |
NO (1) | NO960715D0 (de) |
WO (1) | WO1995006754A1 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5723291A (en) * | 1993-09-01 | 1998-03-03 | The Regents Of The University Of California | Methods for screening compounds for estrogenic activity |
US6156723A (en) | 1993-09-01 | 2000-12-05 | The Regents Of The University Of California | Compositions comprising inhibitors of estrogen response |
GB9424497D0 (en) * | 1994-12-05 | 1995-01-25 | Karobio Ab | Reporter cell line |
WO1997034144A1 (de) * | 1996-03-14 | 1997-09-18 | Schering Aktiengesellschaft | Verfahren zum nachweis der wirkung von testsubstanzen unter verwendung von hühner-urokinase |
US5965543A (en) * | 1996-04-18 | 1999-10-12 | Geron Corporation | Senescence responsive transcriptional element |
US6051417A (en) * | 1996-08-06 | 2000-04-18 | Calydon, Inc. | Prostate cancer drug screening using hKLK2 enhancer |
US5783435A (en) * | 1996-08-06 | 1998-07-21 | Lamparski; Henry G. | Prostate cancer drug screenings |
EP1045035B1 (de) * | 1999-04-14 | 2006-09-20 | Sumitomo Chemical Company, Limited | Zelle zur Bestimmung der Fähigkeit die Aktivität eines Liganden-abhängigen Transkriptionskontrollfaktors zu kontrollieren |
US20110195420A1 (en) * | 2008-10-09 | 2011-08-11 | Merck Patent Gesellschaft | Estrogen and anti-estrogen marker genes |
-
1994
- 1994-09-01 EP EP94927989A patent/EP0724648B1/de not_active Expired - Lifetime
- 1994-09-01 AU AU77190/94A patent/AU682398B2/en not_active Ceased
- 1994-09-01 KR KR1019960701045A patent/KR100355647B1/ko not_active IP Right Cessation
- 1994-09-01 CA CA002169466A patent/CA2169466A1/en not_active Abandoned
- 1994-09-01 WO PCT/US1994/009898 patent/WO1995006754A1/en active IP Right Grant
- 1994-09-01 JP JP50827795A patent/JP3503945B2/ja not_active Expired - Fee Related
- 1994-09-01 DE DE69432422T patent/DE69432422T2/de not_active Expired - Fee Related
- 1994-09-01 AT AT94927989T patent/ATE236247T1/de not_active IP Right Cessation
-
1996
- 1996-02-22 NO NO960715A patent/NO960715D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0724648A1 (de) | 1996-08-07 |
ATE236247T1 (de) | 2003-04-15 |
EP0724648B1 (de) | 2003-04-02 |
DE69432422T2 (de) | 2004-03-04 |
JPH09502345A (ja) | 1997-03-11 |
KR100355647B1 (ko) | 2002-12-28 |
NO960715L (no) | 1996-02-22 |
JP3503945B2 (ja) | 2004-03-08 |
AU682398B2 (en) | 1997-10-02 |
CA2169466A1 (en) | 1995-03-09 |
NO960715D0 (no) | 1996-02-22 |
EP0724648A4 (de) | 1996-10-09 |
WO1995006754A1 (en) | 1995-03-09 |
AU7719094A (en) | 1995-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |