ATE386814T1 - Gemischte g-proteinzusammensetzung und ihre verwendung - Google Patents

Gemischte g-proteinzusammensetzung und ihre verwendung

Info

Publication number
ATE386814T1
ATE386814T1 AT97932210T AT97932210T ATE386814T1 AT E386814 T1 ATE386814 T1 AT E386814T1 AT 97932210 T AT97932210 T AT 97932210T AT 97932210 T AT97932210 T AT 97932210T AT E386814 T1 ATE386814 T1 AT E386814T1
Authority
AT
Austria
Prior art keywords
mixed
protein composition
activation
compositions
protein
Prior art date
Application number
AT97932210T
Other languages
English (en)
Inventor
Paul Negulescu
Stefan Offermanns
Melvin Simon
Charles Zuker
Original Assignee
Invitrogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invitrogen Corp filed Critical Invitrogen Corp
Application granted granted Critical
Publication of ATE386814T1 publication Critical patent/ATE386814T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5041—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving analysis of members of signalling pathways
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
    • C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
    • C12N2830/003—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor tet inducible

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT97932210T 1996-06-21 1997-06-20 Gemischte g-proteinzusammensetzung und ihre verwendung ATE386814T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2023496P 1996-06-21 1996-06-21

Publications (1)

Publication Number Publication Date
ATE386814T1 true ATE386814T1 (de) 2008-03-15

Family

ID=21797473

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97932210T ATE386814T1 (de) 1996-06-21 1997-06-20 Gemischte g-proteinzusammensetzung und ihre verwendung

Country Status (7)

Country Link
US (2) US6004808A (de)
EP (1) EP1012324B1 (de)
AT (1) ATE386814T1 (de)
AU (1) AU3572897A (de)
CA (1) CA2281898C (de)
DE (1) DE69738528D1 (de)
WO (1) WO1997048820A1 (de)

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US20020061556A1 (en) * 2000-04-27 2002-05-23 Walke D. Wade Novel membrane proteins and polynucleotides encoding the same
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US6929925B1 (en) 1999-01-27 2005-08-16 The Regents Of The University Of California Assays for sensory modulators using a sensory cell specific G-protein beta subunit
WO2000045179A2 (en) * 1999-01-27 2000-08-03 The Regents Of The University Of California Screening for modulators of g-protein subunit beta 3
US7067277B1 (en) 1999-12-23 2006-06-27 H. Lundbeck A/S Chimeric G proteins and uses thereof
EP1143017A3 (de) * 2000-04-03 2004-01-28 Warner-Lambert Company LLC Methoden und Zusammensetzungen zum Screenen von icrac Modulatoren
EP1143013A1 (de) * 2000-04-03 2001-10-10 Warner-Lambert Company Verfahren und Zusammenzetzungen zur Screening von ICRAC-Modulatoren
US7264926B2 (en) * 2000-04-18 2007-09-04 Millennium Pharmaceuticals, Inc. Nucleoside Phosphatase
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DE10033353A1 (de) 2000-07-08 2002-01-24 Aventis Pharma Gmbh Breit einsetzbares Verfahren zur Identifizierung von Modulatoren von G-Protein gekoppelten Rezeptoren
US6942988B2 (en) * 2000-09-22 2005-09-13 The Johns Hopkins University School Of Medicine Method of use of sonic hedgehog protein as a ligand for patched
WO2002036622A2 (en) * 2000-10-30 2002-05-10 Senomyx, Inc. GαqPROETIN VARIANTS AND THEIR USE IN THE ANALYSIS AND DISCOVERY OF AGONISTS AND ANTAGONISTS OF CHEMOSENSORY RECEPTORS
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DE60232141D1 (de) * 2001-03-27 2009-06-10 Inscent Inc Effiziente verfahren zur isolierung funktioneller g-protein-gekoppelter rezeptoren und identifizierung aktiver effektoren und effiziente verfahren zur isolierung an der geruchswahrnehmung beteiligter proteine sowie effiziente verfahren zur isolierung und identifizierung aktiver effektoren
US20100248268A1 (en) * 2001-03-27 2010-09-30 Woods Daniel F Methods to utilize invertebrate chemosensory proteins for industrial and commercial uses
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EP2327985B2 (de) 2001-06-26 2019-08-21 Senomyx, Inc. Hetero-oligomere T1R-Geschmacksrezeptoren und diese Rezeptoren exprimierende Zelllinien und deren Verwendung zur Identifizierung von Geschmacksverbindungen
CA2457226C (en) 2001-08-14 2013-02-12 Sentigen Corp. Nucleic acids and proteins of insect or83b odorant receptor genes and uses thereof
US7208290B2 (en) * 2001-12-14 2007-04-24 Senomyx, Inc. Methods of co-expressing umami taste receptors and chimeric Gα15 variants
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EP1685379A4 (de) * 2003-07-11 2007-07-11 Merck & Co Inc Verfahren zur identifizierung von zelloberflächen-rezeptorprotein-modulatoren
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Also Published As

Publication number Publication date
CA2281898A1 (en) 1997-12-24
EP1012324B1 (de) 2008-02-20
WO1997048820A1 (en) 1997-12-24
DE69738528D1 (de) 2008-04-03
EP1012324A1 (de) 2000-06-28
CA2281898C (en) 2007-03-20
US6004808A (en) 1999-12-21
EP1012324A4 (de) 2003-08-13
US20060008855A1 (en) 2006-01-12
AU3572897A (en) 1998-01-07

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