DE69430295D1 - Pulver zur nasalen Verabreichung peptidischer oder proteinischer Arzneistoffe - Google Patents
Pulver zur nasalen Verabreichung peptidischer oder proteinischer ArzneistoffeInfo
- Publication number
- DE69430295D1 DE69430295D1 DE69430295T DE69430295T DE69430295D1 DE 69430295 D1 DE69430295 D1 DE 69430295D1 DE 69430295 T DE69430295 T DE 69430295T DE 69430295 T DE69430295 T DE 69430295T DE 69430295 D1 DE69430295 D1 DE 69430295D1
- Authority
- DE
- Germany
- Prior art keywords
- powder
- nasal administration
- peptide
- protein drugs
- peptidic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 239000000843 powder Substances 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B60—VEHICLES IN GENERAL
- B60H—ARRANGEMENTS OF HEATING, COOLING, VENTILATING OR OTHER AIR-TREATING DEVICES SPECIALLY ADAPTED FOR PASSENGER OR GOODS SPACES OF VEHICLES
- B60H1/00—Heating, cooling or ventilating [HVAC] devices
- B60H1/00485—Valves for air-conditioning devices, e.g. thermostatic valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Mechanical Engineering (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Birds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP20692293 | 1993-07-30 | ||
JP23584193 | 1993-08-30 | ||
JP164494 | 1994-01-12 | ||
PCT/JP1994/001257 WO1995003818A1 (fr) | 1993-07-30 | 1994-07-29 | Poudre permettant l'administration par voie nasale d'un medicament peptidique ou proteique |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69430295D1 true DE69430295D1 (de) | 2002-05-08 |
DE69430295T2 DE69430295T2 (de) | 2002-10-31 |
Family
ID=27275015
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69430295T Expired - Lifetime DE69430295T2 (de) | 1993-07-30 | 1994-07-29 | Pulver zur nasalen Verabreichung peptidischer oder proteinischer Arzneistoffe |
Country Status (9)
Country | Link |
---|---|
US (1) | US5578324A (de) |
EP (1) | EP0667163B1 (de) |
JP (1) | JP2974412B2 (de) |
KR (1) | KR100327563B1 (de) |
AT (1) | ATE215377T1 (de) |
CA (1) | CA2145302C (de) |
DE (1) | DE69430295T2 (de) |
ES (1) | ES2171459T3 (de) |
WO (1) | WO1995003818A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6090925A (en) | 1993-03-09 | 2000-07-18 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5981719A (en) | 1993-03-09 | 1999-11-09 | Epic Therapeutics, Inc. | Macromolecular microparticles and methods of production and use |
US5968899A (en) * | 1994-06-03 | 1999-10-19 | Tsumura & Co. | Medicinal compositions of peptides with EACA or tranexamic acid for enhanced mucosal absorption |
JP3263598B2 (ja) * | 1995-11-01 | 2002-03-04 | 有限会社ドット | 経鼻吸収用生理活性ペプチド組成物 |
CN1155368C (zh) * | 1996-02-27 | 2004-06-30 | 帝人株式会社 | 鼻腔给药的粉剂组合物 |
DE69932144T8 (de) * | 1998-08-26 | 2007-10-04 | Teijin Ltd. | Pulverförmige pernasale mittel |
CA2488497A1 (en) * | 2002-06-11 | 2003-12-18 | The Burnham Institute | Neuroprotective synergy of erythropoietin and insulin-like growth factor |
WO2004084859A2 (en) | 2003-03-21 | 2004-10-07 | Nastech Pharmaceutical Company Inc. | Nasal calcitonin formulations containing chlorobutanol |
JP2008019245A (ja) * | 2006-06-15 | 2008-01-31 | Japan Science & Technology Agency | ヒューマニン誘導体又は該誘導体と神経向性ペプチドとの融合ペプチドを有効成分として含有する、アルツハイマー病予防・治療用の経鼻投与剤 |
RU2723636C1 (ru) * | 2016-11-28 | 2020-06-17 | Пола Кемикал Индастриз, Инк. | Средство для устранения морщин |
JP7102657B2 (ja) * | 2018-05-29 | 2022-07-20 | ポーラ化成工業株式会社 | シワ改善用組成物 |
JP7102658B2 (ja) * | 2018-05-29 | 2022-07-20 | ポーラ化成工業株式会社 | 美白用組成物 |
MX2020012483A (es) * | 2018-05-29 | 2021-02-15 | Pola Chem Ind Inc | Agente de aclaramiento de la piel. |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4258030A (en) * | 1979-03-07 | 1981-03-24 | Zeria-Shinyaku Kogyo Kabushiki Kaisha | Urokinase preparation for oral administration |
DE3514508A1 (de) * | 1985-04-22 | 1986-10-30 | Kailash Kumar Prof. Dr. 2359 Lentföhrden Gauri | Verwendung von dopamin und dessen ester bei der behandlung von glaukom |
JPH01308235A (ja) * | 1988-06-03 | 1989-12-12 | Yamanouchi Pharmaceut Co Ltd | ヒト成長ホルモン経鼻剤 |
GB9013448D0 (en) * | 1990-06-15 | 1990-08-08 | Sandoz Ltd | Pharmaceutical resorption-improved somatostatin compositions,their preparation and use |
JPH04235923A (ja) * | 1991-01-16 | 1992-08-25 | Kyowa Hakko Kogyo Co Ltd | 経鼻投与用製剤 |
JPH04300817A (ja) * | 1991-03-27 | 1992-10-23 | Shiseido Co Ltd | 口腔用組成物 |
JPH0558908A (ja) * | 1991-09-05 | 1993-03-09 | Mitsubishi Kasei Corp | カルシトニン点鼻用医薬組成物 |
JP3090353B2 (ja) * | 1991-09-17 | 2000-09-18 | 旭化成工業株式会社 | パラチロイドホルモン類含有経鼻投与用乳剤 |
JP3047948B2 (ja) * | 1992-12-07 | 2000-06-05 | 株式会社ツムラ | ペプチド類経鼻投与用組成物 |
-
1994
- 1994-07-29 ES ES94921840T patent/ES2171459T3/es not_active Expired - Lifetime
- 1994-07-29 KR KR1019950701216A patent/KR100327563B1/ko not_active IP Right Cessation
- 1994-07-29 WO PCT/JP1994/001257 patent/WO1995003818A1/ja active IP Right Grant
- 1994-07-29 CA CA002145302A patent/CA2145302C/en not_active Expired - Fee Related
- 1994-07-29 US US08/407,000 patent/US5578324A/en not_active Expired - Lifetime
- 1994-07-29 AT AT94921840T patent/ATE215377T1/de not_active IP Right Cessation
- 1994-07-29 DE DE69430295T patent/DE69430295T2/de not_active Expired - Lifetime
- 1994-07-29 JP JP7505744A patent/JP2974412B2/ja not_active Expired - Fee Related
- 1994-07-29 EP EP94921840A patent/EP0667163B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0667163A1 (de) | 1995-08-16 |
JP2974412B2 (ja) | 1999-11-10 |
ES2171459T3 (es) | 2002-09-16 |
US5578324A (en) | 1996-11-26 |
EP0667163A4 (de) | 2000-04-19 |
CA2145302A1 (en) | 1995-02-09 |
KR100327563B1 (ko) | 2002-08-24 |
DE69430295T2 (de) | 2002-10-31 |
WO1995003818A1 (fr) | 1995-02-09 |
KR950703352A (ko) | 1995-09-20 |
EP0667163B1 (de) | 2002-04-03 |
CA2145302C (en) | 2008-10-28 |
ATE215377T1 (de) | 2002-04-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |