DE69429253D1 - Taxane mit pyridyl-substituierter seitenkette - Google Patents
Taxane mit pyridyl-substituierter seitenketteInfo
- Publication number
- DE69429253D1 DE69429253D1 DE69429253T DE69429253T DE69429253D1 DE 69429253 D1 DE69429253 D1 DE 69429253D1 DE 69429253 T DE69429253 T DE 69429253T DE 69429253 T DE69429253 T DE 69429253T DE 69429253 D1 DE69429253 D1 DE 69429253D1
- Authority
- DE
- Germany
- Prior art keywords
- taxane
- pyridyl
- side chain
- substituted side
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 2
- 229940123237 Taxane Drugs 0.000 title 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3485293A | 1993-03-22 | 1993-03-22 | |
| US08/095,085 US5489601A (en) | 1991-09-23 | 1993-07-20 | Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them |
| PCT/US1994/003094 WO1994021252A1 (en) | 1993-03-22 | 1994-03-21 | Taxanes having a pyridyl substituted side-chain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69429253D1 true DE69429253D1 (de) | 2002-01-10 |
| DE69429253T2 DE69429253T2 (de) | 2002-06-13 |
Family
ID=26711461
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69429253T Expired - Fee Related DE69429253T2 (de) | 1993-03-22 | 1994-03-21 | Taxane mit pyridyl-substituierter seitenkette |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0690712B1 (de) |
| JP (1) | JPH08508471A (de) |
| AT (1) | ATE209489T1 (de) |
| AU (1) | AU702492B2 (de) |
| CA (1) | CA2158863C (de) |
| DE (1) | DE69429253T2 (de) |
| DK (1) | DK0690712T3 (de) |
| ES (1) | ES2164100T3 (de) |
| IL (1) | IL109049A (de) |
| PT (1) | PT690712E (de) |
| TW (1) | TW438772B (de) |
| WO (1) | WO1994021252A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19605024A1 (de) * | 1996-01-31 | 1997-08-07 | Schering Ag | Neue selektive Taxane, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| AR030188A1 (es) * | 2000-02-02 | 2003-08-13 | Univ Florida State Res Found | Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos |
| HUP0600302A2 (en) * | 2000-02-02 | 2006-07-28 | Univ Florida State Res Found | C10 ester substituted taxanes as antitumor agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5175315A (en) * | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
| US5227400A (en) * | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
| US5229526A (en) * | 1991-09-23 | 1993-07-20 | Florida State University | Metal alkoxides |
-
1994
- 1994-03-21 IL IL109049A patent/IL109049A/en active IP Right Grant
- 1994-03-21 AT AT94912838T patent/ATE209489T1/de not_active IP Right Cessation
- 1994-03-21 CA CA002158863A patent/CA2158863C/en not_active Expired - Fee Related
- 1994-03-21 DE DE69429253T patent/DE69429253T2/de not_active Expired - Fee Related
- 1994-03-21 ES ES94912838T patent/ES2164100T3/es not_active Expired - Lifetime
- 1994-03-21 JP JP6521329A patent/JPH08508471A/ja not_active Ceased
- 1994-03-21 DK DK94912838T patent/DK0690712T3/da active
- 1994-03-21 PT PT94912838T patent/PT690712E/pt unknown
- 1994-03-21 EP EP94912838A patent/EP0690712B1/de not_active Expired - Lifetime
- 1994-03-21 WO PCT/US1994/003094 patent/WO1994021252A1/en active IP Right Grant
- 1994-06-30 TW TW083105964A patent/TW438772B/zh not_active IP Right Cessation
-
1998
- 1998-03-02 AU AU56373/98A patent/AU702492B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE209489T1 (de) | 2001-12-15 |
| JPH08508471A (ja) | 1996-09-10 |
| EP0690712A4 (de) | 1995-11-20 |
| ES2164100T3 (es) | 2002-02-16 |
| IL109049A (en) | 2006-12-31 |
| AU702492B2 (en) | 1999-02-25 |
| IL109049A0 (en) | 1994-06-24 |
| CA2158863A1 (en) | 1994-09-29 |
| DE69429253T2 (de) | 2002-06-13 |
| EP0690712A1 (de) | 1996-01-10 |
| WO1994021252A1 (en) | 1994-09-29 |
| AU684768B2 (en) | 1998-01-08 |
| AU5637398A (en) | 1998-04-30 |
| DK0690712T3 (da) | 2002-03-18 |
| EP0690712B1 (de) | 2001-11-28 |
| PT690712E (pt) | 2002-05-31 |
| CA2158863C (en) | 2006-12-19 |
| TW438772B (en) | 2001-06-07 |
| AU6522994A (en) | 1994-10-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |