DK0690712T3 - Taxaner med pyridylsubstitueret sidekæde - Google Patents

Taxaner med pyridylsubstitueret sidekæde

Info

Publication number
DK0690712T3
DK0690712T3 DK94912838T DK94912838T DK0690712T3 DK 0690712 T3 DK0690712 T3 DK 0690712T3 DK 94912838 T DK94912838 T DK 94912838T DK 94912838 T DK94912838 T DK 94912838T DK 0690712 T3 DK0690712 T3 DK 0690712T3
Authority
DK
Denmark
Prior art keywords
taxanes
side chain
pyridyl substituted
substituted side
pyridyl
Prior art date
Application number
DK94912838T
Other languages
Danish (da)
English (en)
Inventor
Robert A Holton
Kasthuri Rengan
Original Assignee
Univ Florida State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/095,085 external-priority patent/US5489601A/en
Application filed by Univ Florida State filed Critical Univ Florida State
Application granted granted Critical
Publication of DK0690712T3 publication Critical patent/DK0690712T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK94912838T 1993-03-22 1994-03-21 Taxaner med pyridylsubstitueret sidekæde DK0690712T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3485293A 1993-03-22 1993-03-22
US08/095,085 US5489601A (en) 1991-09-23 1993-07-20 Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
PCT/US1994/003094 WO1994021252A1 (en) 1993-03-22 1994-03-21 Taxanes having a pyridyl substituted side-chain

Publications (1)

Publication Number Publication Date
DK0690712T3 true DK0690712T3 (da) 2002-03-18

Family

ID=26711461

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94912838T DK0690712T3 (da) 1993-03-22 1994-03-21 Taxaner med pyridylsubstitueret sidekæde

Country Status (12)

Country Link
EP (1) EP0690712B1 (de)
JP (1) JPH08508471A (de)
AT (1) ATE209489T1 (de)
AU (1) AU702492B2 (de)
CA (1) CA2158863C (de)
DE (1) DE69429253T2 (de)
DK (1) DK0690712T3 (de)
ES (1) ES2164100T3 (de)
IL (1) IL109049A (de)
PT (1) PT690712E (de)
TW (1) TW438772B (de)
WO (1) WO1994021252A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19605024A1 (de) * 1996-01-31 1997-08-07 Schering Ag Neue selektive Taxane, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung
WO2001057032A1 (en) * 2000-02-02 2001-08-09 Florida State University Research Foundation, Inc. C10 ester substituted taxanes as antitumor agents
CO5280224A1 (es) * 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5229526A (en) * 1991-09-23 1993-07-20 Florida State University Metal alkoxides

Also Published As

Publication number Publication date
CA2158863A1 (en) 1994-09-29
AU5637398A (en) 1998-04-30
ATE209489T1 (de) 2001-12-15
IL109049A0 (en) 1994-06-24
AU684768B2 (en) 1998-01-08
WO1994021252A1 (en) 1994-09-29
DE69429253T2 (de) 2002-06-13
AU6522994A (en) 1994-10-11
JPH08508471A (ja) 1996-09-10
CA2158863C (en) 2006-12-19
AU702492B2 (en) 1999-02-25
ES2164100T3 (es) 2002-02-16
IL109049A (en) 2006-12-31
EP0690712B1 (de) 2001-11-28
DE69429253D1 (de) 2002-01-10
EP0690712A4 (de) 1995-11-20
TW438772B (en) 2001-06-07
PT690712E (pt) 2002-05-31
EP0690712A1 (de) 1996-01-10

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