DE69426988D1 - Transdermale abgabe vorrichtung - Google Patents
Transdermale abgabe vorrichtungInfo
- Publication number
- DE69426988D1 DE69426988D1 DE69426988T DE69426988T DE69426988D1 DE 69426988 D1 DE69426988 D1 DE 69426988D1 DE 69426988 T DE69426988 T DE 69426988T DE 69426988 T DE69426988 T DE 69426988T DE 69426988 D1 DE69426988 D1 DE 69426988D1
- Authority
- DE
- Germany
- Prior art keywords
- methyl
- delivery device
- transdermal delivery
- isoxazole
- pyrrolidinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000037317 transdermal delivery Effects 0.000 title 1
- 239000012790 adhesive layer Substances 0.000 abstract 3
- ILLGYRJAYAAAEW-QMMMGPOBSA-N abt-418 Chemical compound CN1CCC[C@H]1C1=CC(C)=NO1 ILLGYRJAYAAAEW-QMMMGPOBSA-N 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 1
- 238000013271 transdermal drug delivery Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/164,054 US5494680A (en) | 1993-12-08 | 1993-12-08 | Transdermal delivery device |
PCT/US1994/012854 WO1995015754A1 (en) | 1993-12-08 | 1994-11-08 | Transdermal delivery device |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69426988D1 true DE69426988D1 (de) | 2001-05-03 |
DE69426988T2 DE69426988T2 (de) | 2001-11-15 |
Family
ID=22592782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69426988T Expired - Fee Related DE69426988T2 (de) | 1993-12-08 | 1994-11-08 | Transdermale abgabe vorrichtung |
Country Status (15)
Country | Link |
---|---|
US (2) | US5494680A (de) |
EP (1) | EP0732922B1 (de) |
JP (1) | JPH09506365A (de) |
CN (1) | CN1081459C (de) |
AT (1) | ATE200028T1 (de) |
AU (1) | AU678873B2 (de) |
CA (1) | CA2177588A1 (de) |
DE (1) | DE69426988T2 (de) |
DK (1) | DK0732922T3 (de) |
ES (1) | ES2158067T3 (de) |
GR (1) | GR3036144T3 (de) |
IL (1) | IL111648A (de) |
NZ (1) | NZ276597A (de) |
PT (1) | PT732922E (de) |
WO (1) | WO1995015754A1 (de) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU719171B2 (en) * | 1995-01-14 | 2000-05-04 | Abbott Laboratories | A transdermal therapeutic system for the administration of (s)-3-methyl-5-(1-methyl-2-pyrrolidinyl)-isoxazole or one of its pharmaceutically acceptable salts |
DE19501022C1 (de) * | 1995-01-14 | 1996-06-05 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Verabreichung von (s)-3-Methyl-5-(1-methyl-2-pyrrolidenyl)-isoxazol oder einem seiner pharmazeutisch akzeptablen Salze und Verfahren zu seiner Herstellung |
US5730721A (en) | 1996-01-25 | 1998-03-24 | Vesture Corporation | Medical applicator and method |
US6015764A (en) | 1996-12-27 | 2000-01-18 | Kimberly-Clark Worldwide, Inc. | Microporous elastomeric film/nonwoven breathable laminate and method for making the same |
TW526066B (en) * | 1996-12-27 | 2003-04-01 | Kimberly Clark Co | Stable and breathable films of improved toughness, their products, and the method of making the same |
US6111163A (en) | 1996-12-27 | 2000-08-29 | Kimberly-Clark Worldwide, Inc. | Elastomeric film and method for making the same |
US6312715B1 (en) | 1998-05-01 | 2001-11-06 | 3M Innovative Properties Company | Adhesive microsphere drug delivery composition |
US6259730B1 (en) | 1998-11-10 | 2001-07-10 | Lucent Technologies, Inc. | Transmit diversity and reception equalization for radio links |
US6337328B1 (en) | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
KR20010036685A (ko) * | 1999-10-11 | 2001-05-07 | 김윤 | 펜타닐을 함유하는 매트릭스형 경피투여제 |
JP4358978B2 (ja) * | 2000-09-05 | 2009-11-04 | 日東電工株式会社 | 経皮吸収製剤 |
AU2002214364B2 (en) * | 2000-11-06 | 2004-08-19 | Samyang Biopharmaceuticals Corporation | Transdermal drug delivery system with improved water absorbability and adhesion properties |
FR2822711B1 (fr) * | 2001-03-28 | 2003-06-13 | Oreal | Dispositif de traitement comportant une enveloppe definissant une cavite dans laquelle peut-etre engagee une partie du corps |
EP1424972A1 (de) * | 2001-09-14 | 2004-06-09 | 3M Innovative Properties Company | Nicht-kontakt druckverfahren für die herstellung medizinischer drucksensibler artikel |
US6893655B2 (en) | 2001-10-09 | 2005-05-17 | 3M Innovative Properties Co. | Transdermal delivery devices |
AR033748A1 (es) * | 2002-05-15 | 2004-01-07 | Thalas Group Inc | Un dispositivo para la administracion transdermica de sustancias farmacologicamente activas que comprende dos capas adhesivas superpuestas y un procedimiento para prepararlo |
DE10231296A1 (de) | 2002-07-10 | 2004-01-22 | Basf Ag | Verfahren zur Entfernung von Wasser aus einer Mischung, die Wasser und Zinkchlorid enthält |
AU2003268376A1 (en) * | 2002-08-30 | 2004-11-26 | Watson Pharmaceuticals, Inc. | Transdermal delivery systems and methods |
DK1613297T3 (da) * | 2003-04-14 | 2007-09-24 | Lohmann Therapie Syst Lts | Terapeutisk plaster med polysiloxanmatrix indeholdende capsaicin |
US8790689B2 (en) * | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
US20040219195A1 (en) * | 2003-04-30 | 2004-11-04 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
US7182955B2 (en) * | 2003-04-30 | 2007-02-27 | 3M Innovative Properties Company | Abuse-resistant transdermal dosage form |
KR101159828B1 (ko) | 2003-04-30 | 2012-07-04 | 퍼듀 퍼머 엘피 | 활성제 구성요소 및 활성제 층의 원위부에 억제제 구성요소를 포함하는 내변조성 경피제형 |
US20050037194A1 (en) * | 2003-08-15 | 2005-02-17 | Kimberly-Clark Worldwide, Inc. | Thermoplastic polymers with thermally reversible and non-reversible linkages, and articles using same |
US20050065062A1 (en) * | 2003-09-24 | 2005-03-24 | 3M Innovative Properties Company | Method of formulating a pharmaceutical composition |
US20070269522A1 (en) * | 2004-08-20 | 2007-11-22 | Wold Chad R | Transdermal Drug Delivery Device with Translucent Protective Film |
US20060188558A1 (en) * | 2005-02-18 | 2006-08-24 | Mylan Technologies, Inc. | Transdermal systems having control delivery system |
WO2006135785A2 (en) * | 2005-06-10 | 2006-12-21 | Medical College Of Georgia Research Institute | Compositions and methods for treating immune disorders |
US9446017B2 (en) | 2005-08-11 | 2016-09-20 | Augusta University Research Institute, Inc. | Compositions and methods for treating herpes simplex virus |
US9114133B2 (en) | 2006-08-25 | 2015-08-25 | U.S. Dept. Of Veterans Affairs | Method of improving diastolic dysfunction |
DE102007058504A1 (de) | 2007-12-05 | 2009-07-09 | Acino Ag | Transdermales therapeutisches System mit einem Gehalt an einem Modulator für nikotinische Acetylcholinrezeptoren (nAChR) |
NZ589542A (en) * | 2008-05-30 | 2012-10-26 | Mylan Inc | Transdermal drug delivery system comprising an active agent in amorphous form and polyvinylpyrrolidone |
US20130017188A1 (en) | 2009-07-31 | 2013-01-17 | The Brigham And Women's Hospital, Inc. | Modulation of sgk1 expression in th17 cells to modulate th17-mediated immune responses |
CA2794565C (en) | 2010-04-08 | 2018-08-21 | Emory University | Substituted androst-4-ene diones |
CN102486632A (zh) * | 2010-12-01 | 2012-06-06 | 中国石油化工股份有限公司 | 一种对二甲苯氧化过程中对苯二甲酸结晶粒径在线分析方法 |
CA2830069C (en) | 2011-03-20 | 2019-11-12 | The University Of British Columbia | Therapeutic agent for emphysema and copd |
US9480696B2 (en) | 2011-05-04 | 2016-11-01 | Trustees Of Boston University | Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria |
US20140227293A1 (en) | 2011-06-30 | 2014-08-14 | Trustees Of Boston University | Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1) |
EP2543370A1 (de) | 2011-07-06 | 2013-01-09 | Georgia Health Sciences University Research Institute, Inc. | Zusammensetzungen und Verfahren zur Behandlung des Herpes-simplex-Virus |
US9243037B2 (en) | 2011-11-10 | 2016-01-26 | Trustees Of Boston College | Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity |
US20150366890A1 (en) | 2013-02-25 | 2015-12-24 | Trustees Of Boston University | Compositions and methods for treating fungal infections |
EP3036226B1 (de) | 2013-08-22 | 2020-01-08 | The General Hospital Corporation | Hemmer der humanen 12/15-lipoxygenase |
WO2015031765A2 (en) | 2013-08-29 | 2015-03-05 | Trustees Of Boston University | Intermediate metabolism products to potentiate aminoglycoside antibiotics in bacterial infections |
US10010543B1 (en) | 2014-12-23 | 2018-07-03 | Barr Laboratories, Inc. | Transdermal dosage form |
US9486927B1 (en) | 2015-05-20 | 2016-11-08 | Google Inc. | Robotic gripper with multiple pairs of gripping fingers |
WO2016196664A1 (en) | 2015-06-01 | 2016-12-08 | Cedars-Sinai Medical Center | Methods and use of compounds that bind to rela of nf-kb |
BR112018001441A2 (pt) | 2015-07-28 | 2018-09-11 | Vyome Biosciences Pvt Ltd | antibacterianos terapêuticos e profiláticos |
WO2020008370A1 (en) | 2018-07-02 | 2020-01-09 | Clexio Biosciences Ltd. | Transdermal patch |
WO2020008366A1 (en) | 2018-07-02 | 2020-01-09 | Clexio Biosciences Ltd. | Transdermal dosage form |
WO2020009685A1 (en) | 2018-07-02 | 2020-01-09 | John Tang | Transdermal dosage form |
US20230165723A1 (en) | 2020-04-30 | 2023-06-01 | Kindeva Drug Delivery L.P. | Adhesive article and method of making same |
WO2022010864A1 (en) | 2020-07-06 | 2022-01-13 | Kindeva Drug Delivery L.P. | Drug delivery device for delivery of clobetasol propionate |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4060084A (en) * | 1976-09-07 | 1977-11-29 | Alza Corporation | Method and therapeutic system for providing chemotherapy transdermally |
US4751087A (en) * | 1985-04-19 | 1988-06-14 | Riker Laboratories, Inc. | Transdermal nitroglycerin delivery system |
JPS61293911A (ja) * | 1985-06-24 | 1986-12-24 | Teisan Seiyaku Kk | 徐放化製剤 |
US4880633A (en) * | 1986-03-12 | 1989-11-14 | Merck & Co., Inc. | Transdermal drug delivery system |
US5006342A (en) * | 1986-12-22 | 1991-04-09 | Cygnus Corporation | Resilient transdermal drug delivery device |
US5223261A (en) * | 1988-02-26 | 1993-06-29 | Riker Laboratories, Inc. | Transdermal estradiol delivery system |
US4994267A (en) * | 1988-03-04 | 1991-02-19 | Noven Pharmaceuticals, Inc. | Transdermal acrylic multipolymer drug delivery system |
US5176917A (en) * | 1989-03-15 | 1993-01-05 | Lts Lohmann | Transdermal system exhibiting graduated drug release and its use for the local or systemic administration of active substances |
GB9021674D0 (en) * | 1990-10-05 | 1990-11-21 | Ethical Pharma Ltd | Transdermal device |
EP0588917B1 (de) * | 1991-05-29 | 2000-11-08 | Abbott Laboratories | Isoxazol- und isothiazolverbindungen, die die kognitiven funktionen verbesseren |
-
1993
- 1993-12-08 US US08/164,054 patent/US5494680A/en not_active Expired - Lifetime
-
1994
- 1994-11-08 CA CA002177588A patent/CA2177588A1/en not_active Abandoned
- 1994-11-08 JP JP7516192A patent/JPH09506365A/ja not_active Ceased
- 1994-11-08 WO PCT/US1994/012854 patent/WO1995015754A1/en active IP Right Grant
- 1994-11-08 ES ES95901816T patent/ES2158067T3/es not_active Expired - Lifetime
- 1994-11-08 AT AT95901816T patent/ATE200028T1/de not_active IP Right Cessation
- 1994-11-08 PT PT95901816T patent/PT732922E/pt unknown
- 1994-11-08 EP EP95901816A patent/EP0732922B1/de not_active Expired - Lifetime
- 1994-11-08 DE DE69426988T patent/DE69426988T2/de not_active Expired - Fee Related
- 1994-11-08 CN CN94194402A patent/CN1081459C/zh not_active Expired - Fee Related
- 1994-11-08 NZ NZ276597A patent/NZ276597A/en unknown
- 1994-11-08 AU AU10913/95A patent/AU678873B2/en not_active Ceased
- 1994-11-08 DK DK95901816T patent/DK0732922T3/da active
- 1994-11-15 IL IL111648A patent/IL111648A/xx active IP Right Grant
-
1995
- 1995-11-21 US US08/561,406 patent/US5585111A/en not_active Expired - Lifetime
-
2001
- 2001-06-27 GR GR20010400999T patent/GR3036144T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0732922A1 (de) | 1996-09-25 |
WO1995015754A1 (en) | 1995-06-15 |
NZ276597A (en) | 1997-06-24 |
CA2177588A1 (en) | 1995-06-15 |
IL111648A0 (en) | 1995-01-24 |
US5494680A (en) | 1996-02-27 |
JPH09506365A (ja) | 1997-06-24 |
AU678873B2 (en) | 1997-06-12 |
DK0732922T3 (da) | 2001-07-30 |
IL111648A (en) | 1997-09-30 |
US5585111A (en) | 1996-12-17 |
DE69426988T2 (de) | 2001-11-15 |
EP0732922B1 (de) | 2001-03-28 |
PT732922E (pt) | 2001-09-28 |
ES2158067T3 (es) | 2001-09-01 |
AU1091395A (en) | 1995-06-27 |
GR3036144T3 (en) | 2001-09-28 |
CN1081459C (zh) | 2002-03-27 |
ATE200028T1 (de) | 2001-04-15 |
CN1136773A (zh) | 1996-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |