DE69426725D1 - Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren - Google Patents
Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzierenInfo
- Publication number
- DE69426725D1 DE69426725D1 DE69426725T DE69426725T DE69426725D1 DE 69426725 D1 DE69426725 D1 DE 69426725D1 DE 69426725 T DE69426725 T DE 69426725T DE 69426725 T DE69426725 T DE 69426725T DE 69426725 D1 DE69426725 D1 DE 69426725D1
- Authority
- DE
- Germany
- Prior art keywords
- hiv
- peptides
- nucleotide sequences
- sequences
- fusion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 241000713772 Human immunodeficiency virus 1 Species 0.000 title abstract 3
- 230000003472 neutralizing effect Effects 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 4
- 230000004927 fusion Effects 0.000 abstract 3
- 108010067390 Viral Proteins Proteins 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 1
- 101800001690 Transmembrane protein gp41 Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 230000007850 degeneration Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93114631 | 1993-09-11 | ||
| PCT/EP1994/003039 WO1995007354A1 (en) | 1993-09-11 | 1994-09-12 | Peptides that elicit neutralizing antibodies against genetically divergent hiv-1 strains |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69426725D1 true DE69426725D1 (de) | 2001-03-29 |
| DE69426725T2 DE69426725T2 (de) | 2001-09-06 |
Family
ID=8213253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69426725T Expired - Fee Related DE69426725T2 (de) | 1993-09-11 | 1994-09-12 | Peptide, die neutralisierende antikörper gegen genetisch divergierende hiv-1 stämme, induzieren |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0725825B1 (de) |
| JP (1) | JPH09502348A (de) |
| CN (1) | CN1135237A (de) |
| AT (1) | ATE199260T1 (de) |
| AU (1) | AU682893B2 (de) |
| BR (1) | BR9407531A (de) |
| CA (1) | CA2171544C (de) |
| CZ (1) | CZ287808B6 (de) |
| DE (1) | DE69426725T2 (de) |
| ES (1) | ES2156902T3 (de) |
| HU (1) | HU219507B (de) |
| PT (1) | PT725825E (de) |
| RU (1) | RU2181379C2 (de) |
| UA (1) | UA43350C2 (de) |
| WO (1) | WO1995007354A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996033219A1 (en) * | 1995-04-19 | 1996-10-24 | Polymun Scientific Immunbiologische Forschung Gmbh | Monoclonal antibodies against hiv-1 and vaccines made thereof |
| US6319890B1 (en) | 1996-12-30 | 2001-11-20 | Manfred P. Dierich | Inhibition of binding of complement Factor H |
| CA2324348C (en) * | 1998-03-23 | 2006-03-14 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
| US6482928B1 (en) | 1999-04-13 | 2002-11-19 | Aventis Pasteur Limited And University Of Toronto | Fab′-epitope complex from HIV-1 cross-neutralizing monoclonal antibody 2F5 |
| CN1172717C (zh) * | 2000-08-18 | 2004-10-27 | 清华大学 | 一种治疗艾滋病的药物及其制备方法 |
| FR2851165A1 (fr) * | 2003-02-19 | 2004-08-20 | Aventis Pasteur | Antigene derivant de l'helice c de la proteine gp41 |
| CA2604683C (en) | 2005-04-12 | 2019-04-30 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| EP1754715A1 (de) | 2005-08-19 | 2007-02-21 | Bundesrepublik Deutschland vertreten durch das Bundesminsterium für Gesundheit, dieses vertr. durch das Robert-Koch-Institut | Impfstoff auf Basis virusneutralisierender Antikörper |
| WO2008127651A1 (en) | 2007-04-13 | 2008-10-23 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| MX2011007745A (es) * | 2009-02-06 | 2011-12-08 | Mymetics Corp | Division de gp41. |
| US10076567B2 (en) | 2013-09-27 | 2018-09-18 | Duke University | MPER-liposome conjugates and uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69311764T2 (de) * | 1992-05-14 | 1998-02-05 | Polymun Scient Immunbio Forsch | Peptide, die Antikörper induzieren, die genetisch divergierende HIV-1 Isolationen neutralisieren |
| US5817767A (en) * | 1993-02-24 | 1998-10-06 | Progenics Pharmaceuticals, Inc. | Synergistic composition of CD4-based protein and anti-HIV-1 antibody, and methods of using same |
-
1994
- 1994-09-12 UA UA96030897A patent/UA43350C2/uk unknown
- 1994-09-12 PT PT94927602T patent/PT725825E/pt unknown
- 1994-09-12 AT AT94927602T patent/ATE199260T1/de not_active IP Right Cessation
- 1994-09-12 AU AU76965/94A patent/AU682893B2/en not_active Ceased
- 1994-09-12 HU HU9600587A patent/HU219507B/hu not_active IP Right Cessation
- 1994-09-12 CN CN94194035A patent/CN1135237A/zh active Pending
- 1994-09-12 ES ES94927602T patent/ES2156902T3/es not_active Expired - Lifetime
- 1994-09-12 JP JP7508473A patent/JPH09502348A/ja not_active Ceased
- 1994-09-12 RU RU96108781/13A patent/RU2181379C2/ru not_active IP Right Cessation
- 1994-09-12 DE DE69426725T patent/DE69426725T2/de not_active Expired - Fee Related
- 1994-09-12 CZ CZ1996741A patent/CZ287808B6/cs not_active IP Right Cessation
- 1994-09-12 BR BR9407531A patent/BR9407531A/pt not_active Application Discontinuation
- 1994-09-12 EP EP94927602A patent/EP0725825B1/de not_active Expired - Lifetime
- 1994-09-12 CA CA002171544A patent/CA2171544C/en not_active Expired - Fee Related
- 1994-09-12 WO PCT/EP1994/003039 patent/WO1995007354A1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| UA43350C2 (uk) | 2001-12-17 |
| HU219507B (hu) | 2001-04-28 |
| CA2171544C (en) | 2003-06-24 |
| EP0725825B1 (de) | 2001-02-21 |
| EP0725825A1 (de) | 1996-08-14 |
| PT725825E (pt) | 2001-08-30 |
| JPH09502348A (ja) | 1997-03-11 |
| ES2156902T3 (es) | 2001-08-01 |
| CZ287808B6 (en) | 2001-02-14 |
| CA2171544A1 (en) | 1995-03-16 |
| CZ74196A3 (en) | 1996-07-17 |
| WO1995007354A1 (en) | 1995-03-16 |
| ATE199260T1 (de) | 2001-03-15 |
| AU7696594A (en) | 1995-03-27 |
| AU682893B2 (en) | 1997-10-23 |
| DE69426725T2 (de) | 2001-09-06 |
| HU9600587D0 (en) | 1996-05-28 |
| CN1135237A (zh) | 1996-11-06 |
| BR9407531A (pt) | 1997-08-26 |
| RU2181379C2 (ru) | 2002-04-20 |
| HUT76102A (en) | 1997-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |