DE69412101D1 - Verbessertes Verfahren zur Herstellung von Propargyl-Ammonium-Chlorid-Derivaten - Google Patents
Verbessertes Verfahren zur Herstellung von Propargyl-Ammonium-Chlorid-DerivatenInfo
- Publication number
- DE69412101D1 DE69412101D1 DE69412101T DE69412101T DE69412101D1 DE 69412101 D1 DE69412101 D1 DE 69412101D1 DE 69412101 T DE69412101 T DE 69412101T DE 69412101 T DE69412101 T DE 69412101T DE 69412101 D1 DE69412101 D1 DE 69412101D1
- Authority
- DE
- Germany
- Prior art keywords
- ammonium chloride
- iii
- propargyl
- salt
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- IKXNIQJDNKPPCH-UHFFFAOYSA-N hydron;prop-2-yn-1-amine;chloride Chemical class [Cl-].[NH3+]CC#C IKXNIQJDNKPPCH-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001412 amines Chemical class 0.000 abstract 3
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 abstract 2
- 235000011114 ammonium hydroxide Nutrition 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- FEWJPZIEWOKRBE-LWMBPPNESA-L D-tartrate(2-) Chemical compound [O-]C(=O)[C@@H](O)[C@H](O)C([O-])=O FEWJPZIEWOKRBE-LWMBPPNESA-L 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 159000000011 group IA salts Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 239000012044 organic layer Substances 0.000 abstract 1
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 abstract 1
- -1 propargyl halide Chemical class 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
- C07C209/08—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treatment Of Steel In Its Molten State (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9403342A HU218927B (hu) | 1994-11-22 | 1994-11-22 | Eljárás propargil-ammónium-klorid-származékok előállítására |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69412101D1 true DE69412101D1 (de) | 1998-09-03 |
| DE69412101T2 DE69412101T2 (de) | 1999-01-14 |
Family
ID=10985778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69412101T Expired - Lifetime DE69412101T2 (de) | 1994-11-22 | 1994-12-09 | Verbessertes Verfahren zur Herstellung von Propargyl-Ammonium-Chlorid-Derivaten |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5449828A (de) |
| EP (1) | EP0713858B1 (de) |
| AT (1) | ATE168987T1 (de) |
| CA (1) | CA2137761C (de) |
| CZ (1) | CZ289827B6 (de) |
| DE (1) | DE69412101T2 (de) |
| DK (1) | DK0713858T3 (de) |
| ES (1) | ES2119990T3 (de) |
| GR (1) | GR3027708T3 (de) |
| HU (1) | HU218927B (de) |
| IL (1) | IL113298A (de) |
| RU (1) | RU2130450C1 (de) |
| UA (1) | UA39938C2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7456318B2 (en) * | 2005-01-06 | 2008-11-25 | Mallinckrodt Inc. | Process for preparing benzylated amines |
| CN102775317A (zh) * | 2012-07-09 | 2012-11-14 | 盐城工学院 | 一种制备烯丙基二甲基脱氢枞基氯化铵的方法 |
| CN102816074A (zh) * | 2012-08-27 | 2012-12-12 | 万隆化工有限公司 | 一种对正丁基苯胺的合成方法 |
| CN102850227B (zh) * | 2012-09-19 | 2015-05-13 | 常州胜杰化工有限公司 | 前手性烯丙基胺类化合物及其合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1121857A (en) * | 1965-01-05 | 1968-07-31 | Science Union & Cie | New phenylisopropylamine derivatives and process for their preparation and pharmaceutical preparations of such derivatives |
| US3485874A (en) * | 1966-05-04 | 1969-12-23 | Chinoin Gyogyszer Es Vegyeszet | Ortho and para bromophenyl isopropyl methylamines |
| US3496195A (en) * | 1966-05-11 | 1970-02-17 | Chinoin Gyogyszer Es Vegyeszet | D-o-bromo-phenyl-isopropyl-methylpropinylamine and its salts |
| HU187775B (en) * | 1982-07-14 | 1986-02-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | New process for producing propargile-amines of pharmaceutical activity |
| HU207282B (en) * | 1984-05-31 | 1993-03-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them |
-
1994
- 1994-11-22 HU HU9403342A patent/HU218927B/hu not_active IP Right Cessation
- 1994-12-08 UA UA94129143A patent/UA39938C2/uk unknown
- 1994-12-08 CZ CZ19943094A patent/CZ289827B6/cs not_active IP Right Cessation
- 1994-12-09 US US08/353,816 patent/US5449828A/en not_active Expired - Lifetime
- 1994-12-09 RU RU94043796A patent/RU2130450C1/ru not_active IP Right Cessation
- 1994-12-09 EP EP94890207A patent/EP0713858B1/de not_active Expired - Lifetime
- 1994-12-09 DE DE69412101T patent/DE69412101T2/de not_active Expired - Lifetime
- 1994-12-09 DK DK94890207T patent/DK0713858T3/da active
- 1994-12-09 ES ES94890207T patent/ES2119990T3/es not_active Expired - Lifetime
- 1994-12-09 CA CA002137761A patent/CA2137761C/en not_active Expired - Fee Related
- 1994-12-09 AT AT94890207T patent/ATE168987T1/de active
-
1995
- 1995-04-07 IL IL11329895A patent/IL113298A/xx not_active IP Right Cessation
-
1998
- 1998-08-20 GR GR980401885T patent/GR3027708T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU218927B (hu) | 2000-12-28 |
| RU2130450C1 (ru) | 1999-05-20 |
| HUT74016A (en) | 1996-10-28 |
| HU9403342D0 (en) | 1995-02-28 |
| EP0713858B1 (de) | 1998-07-29 |
| IL113298A0 (en) | 1995-07-31 |
| EP0713858A1 (de) | 1996-05-29 |
| ATE168987T1 (de) | 1998-08-15 |
| CA2137761A1 (en) | 1996-05-23 |
| DE69412101T2 (de) | 1999-01-14 |
| US5449828A (en) | 1995-09-12 |
| GR3027708T3 (en) | 1998-11-30 |
| IL113298A (en) | 1999-09-22 |
| RU94043796A (ru) | 1996-10-10 |
| CZ289827B6 (cs) | 2002-04-17 |
| DK0713858T3 (da) | 1998-11-16 |
| CA2137761C (en) | 1998-05-12 |
| UA39938C2 (uk) | 2001-07-16 |
| CZ309494A3 (en) | 1996-06-12 |
| ES2119990T3 (es) | 1998-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: CHINOIN PHARMACEUTICAL AND CHEMICAL WORKS PRIV, HU |