DE69409811D1 - Neue vitamin d-derivate - Google Patents

Neue vitamin d-derivate

Info

Publication number
DE69409811D1
DE69409811D1 DE69409811T DE69409811T DE69409811D1 DE 69409811 D1 DE69409811 D1 DE 69409811D1 DE 69409811 T DE69409811 T DE 69409811T DE 69409811 T DE69409811 T DE 69409811T DE 69409811 D1 DE69409811 D1 DE 69409811D1
Authority
DE
Germany
Prior art keywords
pct
formula
sec
hydrogen
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69409811T
Other languages
English (en)
Other versions
DE69409811T2 (de
Inventor
Gunnar Grue-Sorensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Publication of DE69409811D1 publication Critical patent/DE69409811D1/de
Application granted granted Critical
Publication of DE69409811T2 publication Critical patent/DE69409811T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Dental Preparations (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69409811T 1993-07-12 1994-07-01 Neue vitamin d-derivate Expired - Fee Related DE69409811T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939314400A GB9314400D0 (en) 1993-07-12 1993-07-12 Produktionsaktieselskab) chemical compounds
PCT/DK1994/000271 WO1995002577A1 (en) 1993-07-12 1994-07-01 Novel vitamin d analogues

Publications (2)

Publication Number Publication Date
DE69409811D1 true DE69409811D1 (de) 1998-05-28
DE69409811T2 DE69409811T2 (de) 1999-01-07

Family

ID=10738689

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409811T Expired - Fee Related DE69409811T2 (de) 1993-07-12 1994-07-01 Neue vitamin d-derivate

Country Status (15)

Country Link
US (1) US5716945A (de)
EP (1) EP0708755B1 (de)
JP (1) JP3773253B2 (de)
KR (1) KR100317869B1 (de)
CN (1) CN1048241C (de)
AT (1) ATE165346T1 (de)
AU (1) AU690564B2 (de)
CA (1) CA2162040A1 (de)
DE (1) DE69409811T2 (de)
ES (1) ES2117281T3 (de)
FI (1) FI111719B (de)
GB (1) GB9314400D0 (de)
NZ (1) NZ268567A (de)
RU (1) RU2130926C1 (de)
WO (1) WO1995002577A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
DE19619036A1 (de) * 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
WO1998001135A1 (fr) * 1996-07-03 1998-01-15 Sanwa Kagaku Kenkyusho Co., Ltd. Agents d'elimination du phosphore, inhibiteurs augmentant le taux serique de parathormone et inhibiteurs de l'osteodystrophie
EP1011683A4 (de) 1997-05-22 2003-06-11 Cephalon Inc Vitamin d analoge und der wirkung auf neuronen
CA2296145A1 (en) * 1997-07-17 1999-01-28 F. Hoffmann-La Roche Ag Dihomo-seco-cholestanes with two unsaturated bonds in the side chain
HU230045B1 (hu) * 1999-04-23 2015-06-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Bőrgyógyászati alkalmazásra szolgáló nem vizes gyógyszerkészítmény
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
CA2385755C (en) 1999-09-29 2007-02-06 Colotech A/S Prevention of colorectal cancer
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US20020183277A1 (en) * 2001-05-15 2002-12-05 Lise Binderup Combination of vitamin D analogue and pyrimidine nucleoside analogue
AR041696A1 (es) * 2002-10-23 2005-05-26 Leo Pharm Prod Ltd Compuestos analogos de vitamina d, composiciones que comprenden dichos compuestos analogos y su uso
EP1556345B1 (de) * 2002-10-23 2010-12-15 Leo Pharma A/S Vitamin-d-analoga, zusammensetzungen, die diese analoga enthalten und deren verwendung
EP1458678A1 (de) * 2002-11-18 2004-09-22 Teva Pharmaceutical Industries Limited Kristallisationsverfahren zur reinigung von calcipotriene
ES2234423B1 (es) * 2003-12-05 2006-03-01 Laboratorios Viñas, S.A. Procedimiento para la obtencion de derivados de vitamina d a partir de compuestos monohalogenovinilicos.
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
EA026334B1 (ru) 2009-01-27 2017-03-31 БЕРГ ЭлЭлСи Применение соединения витамина d для предотвращения или снижения развития химиотерапевтически индуцированной нейтропении
CN102655869B (zh) 2009-08-14 2016-08-10 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
CN112156097A (zh) 2013-05-29 2021-01-01 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发
CN103508999B (zh) * 2013-10-12 2015-05-13 浙江海正药业股份有限公司 马沙骨化醇的合成中间体及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
AU614372B2 (en) * 1988-04-21 1991-08-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Novel vitamin d analogues
US5378695A (en) * 1989-02-23 1995-01-03 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Vitamin D analogues
GB8915770D0 (en) * 1989-07-10 1989-08-31 Leo Pharm Prod Ltd Chemical compounds
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
GB9223061D0 (en) * 1992-11-04 1992-12-16 Leo Pharm Prod Ltd Chemical compounds
GB9226877D0 (en) * 1992-12-23 1993-02-17 Leo Pharm Prod Ltd Chemical compounds
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds

Also Published As

Publication number Publication date
EP0708755B1 (de) 1998-04-22
ES2117281T3 (es) 1998-08-01
KR960702436A (ko) 1996-04-27
CN1048241C (zh) 2000-01-12
RU2130926C1 (ru) 1999-05-27
AU690564B2 (en) 1998-04-30
GB9314400D0 (en) 1993-08-25
FI111719B (fi) 2003-09-15
AU7182994A (en) 1995-02-13
FI956108A0 (fi) 1995-12-19
CN1125941A (zh) 1996-07-03
JPH08512327A (ja) 1996-12-24
JP3773253B2 (ja) 2006-05-10
KR100317869B1 (ko) 2002-09-27
EP0708755A1 (de) 1996-05-01
WO1995002577A1 (en) 1995-01-26
NZ268567A (en) 1997-11-24
DE69409811T2 (de) 1999-01-07
US5716945A (en) 1998-02-10
CA2162040A1 (en) 1995-01-26
FI956108A (fi) 1995-12-19
ATE165346T1 (de) 1998-05-15

Similar Documents

Publication Publication Date Title
DE69409811T2 (de) Neue vitamin d-derivate
ATE150013T1 (de) Vitamin d derivate
ES2098031T3 (es) Nuevos analogos de vitamina d.
DE69714590D1 (de) Vitamin d analoge verbindungen
DE69712086T2 (de) Vitamin d derivate
DE69608701T2 (de) Vitamin d analoge

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LEO PHARMA A/S ZWEITNAME: LEO PHARMACEUTICAL PRODU

8339 Ceased/non-payment of the annual fee