DE69405930D1 - Automatisches Auflösungsuntersuchungssystem - Google Patents

Automatisches Auflösungsuntersuchungssystem

Info

Publication number
DE69405930D1
DE69405930D1 DE69405930T DE69405930T DE69405930D1 DE 69405930 D1 DE69405930 D1 DE 69405930D1 DE 69405930 T DE69405930 T DE 69405930T DE 69405930 T DE69405930 T DE 69405930T DE 69405930 D1 DE69405930 D1 DE 69405930D1
Authority
DE
Germany
Prior art keywords
investigation system
automatic resolution
resolution investigation
automatic
resolution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69405930T
Other languages
English (en)
Other versions
DE69405930T2 (de
Inventor
Burleigh M Hutchins
Randall B Rubinstein
Barry T Hixon
William J Buote
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymark Corp
Original Assignee
Zymark Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymark Corp filed Critical Zymark Corp
Application granted granted Critical
Publication of DE69405930D1 publication Critical patent/DE69405930D1/de
Publication of DE69405930T2 publication Critical patent/DE69405930T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00—Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/006—Dissolution of tablets or the like
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00188—Special arrangements of analysers the analyte being in the solid state
    • G01N2035/00198—Dissolution analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
DE69405930T 1993-07-14 1994-07-13 Automatisches Auflösungsuntersuchungssystem Expired - Fee Related DE69405930T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9184893A 1993-07-14 1993-07-14

Publications (2)

Publication Number Publication Date
DE69405930D1 true DE69405930D1 (de) 1997-11-06
DE69405930T2 DE69405930T2 (de) 1998-02-12

Family

ID=22229935

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69405930T Expired - Fee Related DE69405930T2 (de) 1993-07-14 1994-07-13 Automatisches Auflösungsuntersuchungssystem

Country Status (4)

Country Link
US (1) US6060024A (de)
EP (1) EP0635713B1 (de)
DE (1) DE69405930T2 (de)
HK (1) HK1003845A1 (de)

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US5948360A (en) 1994-07-11 1999-09-07 Tekmar Company Autosampler with robot arm
EP0770212A1 (de) * 1994-07-11 1997-05-02 Tekmar Company Modul, bestehend aus einer aus probegefaessen selbsttaetig proben nehmende vorrichtung
DE29519713U1 (de) * 1995-12-12 1996-02-01 Erweka GmbH, 63150 Heusenstamm Dissolutionstestgerät
US5985214A (en) 1997-05-16 1999-11-16 Aurora Biosciences Corporation Systems and methods for rapidly identifying useful chemicals in liquid samples
US6528026B2 (en) 1998-08-13 2003-03-04 Symyx Technologies, Inc. Multi-temperature modular reactor and method of using same
US6306658B1 (en) 1998-08-13 2001-10-23 Symyx Technologies Parallel reactor with internal sensing
US6548026B1 (en) 1998-08-13 2003-04-15 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
US6864092B1 (en) 1998-08-13 2005-03-08 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
US6455316B1 (en) 1998-08-13 2002-09-24 Symyx Technologies, Inc. Parallel reactor with internal sensing and method of using same
EP1260267A3 (de) * 1998-08-13 2005-09-21 Symyx Technologies Verfahren zur parallelen Behandlung von Reaktionsgemischen
EP1052498A1 (de) * 1999-05-11 2000-11-15 Sotax Ag Verfahren, Patrone und Vorrichtung zum Einbringen eines teilchenförmigen Materials in eine Flüssigkeit
EP1200185A2 (de) * 1999-06-25 2002-05-02 Avantium International B.V. Reaktionsbehälterreihe
NO312921B1 (no) * 1999-07-05 2002-07-15 Sinvent As Multitest-sammenstilling for evaluering, detektering og overvåkning av prosesser ved forhöyet trykk
EP1310297A3 (de) * 2000-06-03 2005-11-23 Symyx Technologies, Inc. Semikontinuierliche oder kontinuierliche Parallelreaktoren mit zweiteligen Zuleitungen
AU2001265336A1 (en) * 2000-06-03 2001-12-17 Symyx Technologies, Inc. Parallel semicontinuous or continuous reactors
US6994827B2 (en) * 2000-06-03 2006-02-07 Symyx Technologies, Inc. Parallel semicontinuous or continuous reactors
US6490782B1 (en) 2000-10-16 2002-12-10 Varian, Inc. Automated in-line filter changing apparatus
US6962674B2 (en) * 2001-02-28 2005-11-08 Varian, Inc. Dissolution test apparatus
US6336739B1 (en) * 2001-03-02 2002-01-08 Luke Lee Air bath dissolution tester
US6692708B2 (en) 2001-04-05 2004-02-17 Symyx Technologies, Inc. Parallel reactor for sampling and conducting in situ flow-through reactions and a method of using same
US6652135B2 (en) * 2001-09-24 2003-11-25 Highland Laboratories, Inc. Stirring apparatus for large containers
US6582116B2 (en) 2001-09-24 2003-06-24 Symyx Technologies, Inc. Apparatus and method for mixing small volumes of reaction materials
CA2462737C (en) * 2001-10-11 2009-12-15 Elan Pharma International Limited Apparatus and method for concurrently monitoring active release and physical appearance of solid dosage form pharmaceuticals
US6764651B2 (en) * 2001-11-07 2004-07-20 Varian, Inc. Fiber-optic dissolution systems, devices, and methods
US6950568B2 (en) * 2002-02-14 2005-09-27 Varian, Inc. Fiber-optic channel selecting apparatus
US6611334B1 (en) 2002-02-14 2003-08-26 Varian, Inc. Sample analysis system with fiber optics and related method
US20030190260A1 (en) * 2002-04-05 2003-10-09 Symyx Technologies, Inc. Combinatorial chemistry reactor system
US20040115822A1 (en) * 2002-09-12 2004-06-17 Schapaugh Randal Lee Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
US20040115837A1 (en) * 2002-11-27 2004-06-17 Schapaugh Randal Lee Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
US7024955B2 (en) * 2003-03-01 2006-04-11 Symyx Technologies, Inc. Methods and systems for dissolution testing
US20060002824A1 (en) * 2004-06-07 2006-01-05 Irm, Llc Dispensing systems, software, and related methods
DE102004062166B4 (de) * 2004-12-20 2007-03-22 Anatox Gmbh & Co. Kg Vorrichtung zur Probenentnahme und zum Probentransfer
JP4764661B2 (ja) * 2005-05-17 2011-09-07 日本分光株式会社 溶出試験器
US7331251B2 (en) * 2005-06-22 2008-02-19 Idaho State University Dissolution testing of solid dosage forms intended to be administered in the oral cavity
EP3208272B1 (de) 2005-11-08 2020-01-08 Vertex Pharmaceuticals Incorporated Heterocyclische modulatoren von atp-bindenden kassettentransportern
WO2007079257A2 (en) * 2005-12-30 2007-07-12 Caliper Life Sciences, Inc. Integrated dissolution processing and sample transfer system
GB2436143A (en) * 2006-03-15 2007-09-19 Astech Projects Ltd Multiple sample processing
US7585465B2 (en) * 2006-06-15 2009-09-08 Logan Instruments Corp. Pharmaceutical product release rate testing device
US7914741B2 (en) * 2007-01-10 2011-03-29 Agilent Technologies, Inc. Automated microsampling dissolution test system
US20090155920A1 (en) * 2007-11-12 2009-06-18 Symyx Technologies, Inc. High throughput dissolution and precipitation apparatus and method
DE102007058718A1 (de) * 2007-12-06 2009-06-10 Erweka Gmbh Vorrichtung und Verfahren zur automatischen Freisetzung und Messung von Wirkstoffen aus einer Arzneizubereitung
CN101721937B (zh) * 2008-10-31 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 搅拌系统及其工作方法
DE102008058514A1 (de) 2008-11-21 2010-05-27 Boehringer Ingelheim International Gmbh Vorrichtung zur Vorbeurteilung von Eigenschaften von Zusammensetzungen, insbesondere Screening-Vorrichtung und Verfahren zur Formulierungsfindung
WO2010091739A1 (de) * 2009-02-16 2010-08-19 Erweka Gmbh Verfahren und system zur automatischen analyse von freisetzungsproben
NZ602838A (en) 2010-04-07 2015-06-26 Vertex Pharma Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid and administration thereof
JP5576337B2 (ja) * 2010-06-30 2014-08-20 ローム アンド ハース カンパニー 医薬剤形を溶出試験装置に分配するための送達装置
US9050548B2 (en) 2010-12-22 2015-06-09 Agilent Technologies, Inc. Multi-channel filter assembly and related apparatus and methods
JP5773914B2 (ja) * 2011-03-11 2015-09-02 ディステック，インコーポレーテッド 中央制御されたモジュール式のモーター式試験
CN103048182A (zh) * 2011-10-15 2013-04-17 四川汇利实业有限公司 能够快速进行溶解度测试的除氧气装置
CN104807726B (zh) * 2014-01-23 2018-03-02 成都中医药大学附属医院 压制中药饮片浸散时限的检测方法
CN104353378B (zh) * 2014-10-22 2016-03-30 浙江中烟工业有限责任公司 一种试管搅拌装置
RU2691136C2 (ru) * 2014-11-18 2019-06-11 Вертекс Фармасьютикалз Инкорпорейтед Способ проведения высокопроизводительной тестовой высокоэффективной жидкостной хроматографии
US10228358B2 (en) 2015-04-17 2019-03-12 Pion Inc. Apparatus and method for the assessment of concentration profiling and permeability rates
WO2019038928A1 (ja) * 2017-08-25 2019-02-28 株式会社島津製作所 液体クロマトグラフ及び溶出試験システム
GB2603534B (en) * 2021-02-09 2023-08-16 Agilent Technologies Inc Horizontally adjustable sample taker for dissolution apparatus
CN114113512B (zh) * 2021-12-13 2023-10-27 广州仁恒制药有限公司 一种液体药品检测设备

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4335438A (en) * 1980-04-17 1982-06-15 Smolen Victor F Method and apparatus for automatic dissolution testing of products
US4279860A (en) * 1980-06-25 1981-07-21 Smolen Victor F Multiple injector flow through dissolution cell for dissolution testing apparatus
US4578244A (en) * 1982-04-23 1986-03-25 Pharmacontrol Corp. Sampling apparatus for obtaining a plurality of fluid samples
DE3520034C1 (de) * 1985-06-04 1986-05-07 Erweka Apparatebau GmbH, 6056 Heusenstamm Zerfallstestgeraet
EP0278374A3 (de) * 1987-02-06 1989-03-01 Pharmatest Apparatebau Gmbh Vorrichtung zur Bestimmung der Wirkstoff-Freigabe von pharmazeutischen Produkten
ES2011758T3 (es) * 1988-05-19 1993-04-01 Erweka Gmbh Aparato para la comprobacion de disoluciones.
US5076107A (en) * 1988-12-27 1991-12-31 G. D. Searle & Co. Apparatus and method for resultant-weight measuring system

Also Published As

Publication number Publication date
EP0635713B1 (de) 1997-10-01
US6060024A (en) 2000-05-09
HK1003845A1 (en) 1998-11-06
DE69405930T2 (de) 1998-02-12
EP0635713A1 (de) 1995-01-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee