DE69334097D1 - Serumfreies Medium - Google Patents

Serumfreies Medium

Info

Publication number
DE69334097D1
DE69334097D1 DE69334097T DE69334097T DE69334097D1 DE 69334097 D1 DE69334097 D1 DE 69334097D1 DE 69334097 T DE69334097 T DE 69334097T DE 69334097 T DE69334097 T DE 69334097T DE 69334097 D1 DE69334097 D1 DE 69334097D1
Authority
DE
Germany
Prior art keywords
free medium
serum
medium
thrombin
insulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69334097T
Other languages
English (en)
Other versions
DE69334097T2 (de
Inventor
Dina Fischer
Moshe Bracha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Interpharm Laboratories Ltd
Original Assignee
Interpharm Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interpharm Laboratories Ltd filed Critical Interpharm Laboratories Ltd
Application granted granted Critical
Publication of DE69334097D1 publication Critical patent/DE69334097D1/de
Publication of DE69334097T2 publication Critical patent/DE69334097T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/76—Undefined extracts from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/24—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/25—Tumour necrosing factors [TNF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE1993634097 1992-08-24 1993-08-24 Serumfreies Medium für Säugetierzellen Expired - Lifetime DE69334097T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL10292992A IL102929A (en) 1992-08-24 1992-08-24 Serum-free medium for mammalian cells
IL10292992 1992-08-24

Publications (2)

Publication Number Publication Date
DE69334097D1 true DE69334097D1 (de) 2007-01-25
DE69334097T2 DE69334097T2 (de) 2007-07-12

Family

ID=11063947

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1993634097 Expired - Lifetime DE69334097T2 (de) 1992-08-24 1993-08-24 Serumfreies Medium für Säugetierzellen
DE1993632430 Expired - Lifetime DE69332430T2 (de) 1992-08-24 1993-08-24 Serumfreies Medium für Säugetierzellen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1993632430 Expired - Lifetime DE69332430T2 (de) 1992-08-24 1993-08-24 Serumfreies Medium für Säugetierzellen

Country Status (13)

Country Link
US (1) US5641647A (de)
EP (2) EP1045023B1 (de)
JP (1) JP4124493B2 (de)
AT (2) ATE348147T1 (de)
AU (1) AU670957B2 (de)
CA (1) CA2104643C (de)
CY (1) CY2572B1 (de)
DE (2) DE69334097T2 (de)
DK (2) DK0584788T3 (de)
ES (2) ES2185618T3 (de)
IL (1) IL102929A (de)
PT (2) PT1045023E (de)
ZA (1) ZA936192B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1482031B1 (de) * 1996-08-30 2015-10-28 Life Technologies Corporation Serumfreies Kulturmedium für Säugerzellen und seine Verwendung
US6692961B1 (en) * 1996-10-11 2004-02-17 Invitrogen Corporation Defined systems for epithelial cell culture and use thereof
AU7637796A (en) * 1996-12-09 1998-07-03 James Edwin Bailey Expression of active interferon beta 1 using recombinant rna replicons
SE9700983D0 (sv) * 1997-03-18 1997-03-18 Ascendia Ab Stimulering, odling och preservation av pankreas- och andra celler
IL143243A0 (en) * 1998-11-19 2002-04-21 Organogenesis Inc A cultured tissue construct containing fibroblast cells and methods for the production thereof
UA74557C2 (en) 1999-09-03 2006-01-16 Applied Research Systems A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
EP1754784A3 (de) * 1999-09-03 2007-02-28 Applied Research Systems ARS Holding N.V. Verfahren zur Produktion eines heterologen sezernierten Proteins aus auf Mikroträgern gewachsenen Cho-Zellen
US7445924B2 (en) 2000-11-23 2008-11-04 Bavarian Nordic A/S Modified Vaccinia Ankara virus variant and cultivation method
US6506576B2 (en) 2001-03-14 2003-01-14 Board Of Trustees Of The University Of Arkansas Serum-and steroid-free culture media for cerebellar granule neurons
CN1692156B (zh) 2002-09-05 2011-05-11 巴法里安诺迪克有限公司 在无血清条件下培养原代细胞和扩增病毒的方法
EP2407561A3 (de) * 2006-03-06 2012-05-30 Humagene, Inc. Verfahren zur Herstellung von rekombinantem menschlichem Fibrinogen
US8415094B2 (en) * 2007-12-21 2013-04-09 Jaffar Ali bin M. Abdullah Protein-free gamete and embryo handling and culture media products
CN103898123B (zh) * 2012-12-28 2019-03-15 北京韩美药品有限公司 重组人IFN-β-1a及其生产和纯化方法
US9404078B2 (en) 2013-03-08 2016-08-02 Neuclone Biologics Pty Ltd Cell expression system
AU2014225273A1 (en) * 2013-03-08 2015-09-24 Neuclone Biologics Pty Ltd Cell culture media composition and methods of producing thereof
CN103484426B (zh) * 2013-10-15 2014-11-26 齐鲁制药有限公司 一种无动物源的低蛋白培养基
US9534026B2 (en) 2013-10-31 2017-01-03 China National Research Institute Of Food & Fermentation Industries Corn active peptide additive for cell culture medium
CN104593318B (zh) * 2013-10-31 2018-05-04 中国食品发酵工业研究院 一种用于细胞培养基的玉米活性肽添加剂
JP2021180620A (ja) * 2020-05-18 2021-11-25 株式会社マイオリッジ 目的細胞の生産方法、目的細胞による生産物の生産方法、および無血清培地

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621972B2 (en) * 1988-12-14 1992-03-26 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cell culture medium for human liver epithelial cell line
ZA901280B (en) * 1989-02-27 1991-10-30 Lilly Co Eli Tissue culture method
GB9022545D0 (en) * 1990-10-17 1990-11-28 Wellcome Found Culture medium
US5256766A (en) * 1991-02-19 1993-10-26 The Regents Of The University Of California Recombinant thrombin receptor and related pharmaceuticals

Also Published As

Publication number Publication date
ZA936192B (en) 1994-03-22
DK0584788T3 (da) 2003-02-24
EP0584788B1 (de) 2002-10-23
CA2104643A1 (en) 1994-02-25
ES2274756T3 (es) 2007-06-01
JPH06153931A (ja) 1994-06-03
EP1045023A1 (de) 2000-10-18
EP0584788A2 (de) 1994-03-02
US5641647A (en) 1997-06-24
DE69332430T2 (de) 2003-07-17
ATE348147T1 (de) 2007-01-15
IL102929A0 (en) 1993-01-31
EP1045023B1 (de) 2006-12-13
PT1045023E (pt) 2007-02-28
DE69334097T2 (de) 2007-07-12
DE69332430D1 (de) 2002-11-28
CY2572B1 (en) 2008-07-02
JP4124493B2 (ja) 2008-07-23
CA2104643C (en) 2009-07-21
PT584788E (pt) 2003-02-28
ES2185618T3 (es) 2003-05-01
AU4487193A (en) 1994-03-03
IL102929A (en) 1996-11-14
EP0584788A3 (de) 1995-01-18
AU670957B2 (en) 1996-08-08
ATE226632T1 (de) 2002-11-15
DK1045023T3 (da) 2007-03-12

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Legal Events

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