DE69333627D1 - Rekombinanter anti-hiv antikörper und seine herstellung - Google Patents

Rekombinanter anti-hiv antikörper und seine herstellung

Info

Publication number
DE69333627D1
DE69333627D1 DE69333627T DE69333627T DE69333627D1 DE 69333627 D1 DE69333627 D1 DE 69333627D1 DE 69333627 T DE69333627 T DE 69333627T DE 69333627 T DE69333627 T DE 69333627T DE 69333627 D1 DE69333627 D1 DE 69333627D1
Authority
DE
Germany
Prior art keywords
antibody
hiv
codes
activity
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69333627T
Other languages
English (en)
Other versions
DE69333627T2 (de
Inventor
Hiroaki Maeda
Kazuhiko Kimachi
Yasuyuki Eda
Kouichi Shiosaki
Kiyoshi Osatomi
Sachio Tokiyoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Publication of DE69333627D1 publication Critical patent/DE69333627D1/de
Application granted granted Critical
Publication of DE69333627T2 publication Critical patent/DE69333627T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE69333627T 1993-01-14 1993-01-14 Rekombinanter anti-hiv antikörper und seine herstellung Expired - Fee Related DE69333627T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/JP1993/000039 WO1994015969A1 (en) 1993-01-14 1993-01-14 Recombinant anti-hiv antibody and preparation thereof
CA002153165A CA2153165C (en) 1993-01-14 1993-01-14 Recombinant anti-hiv antibody and process for preparing the same

Publications (2)

Publication Number Publication Date
DE69333627D1 true DE69333627D1 (de) 2004-10-21
DE69333627T2 DE69333627T2 (de) 2005-09-22

Family

ID=25678063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333627T Expired - Fee Related DE69333627T2 (de) 1993-01-14 1993-01-14 Rekombinanter anti-hiv antikörper und seine herstellung

Country Status (10)

Country Link
US (1) US5773247A (de)
EP (1) EP0678523B1 (de)
AT (1) ATE276276T1 (de)
AU (1) AU671608B2 (de)
CA (1) CA2153165C (de)
DE (1) DE69333627T2 (de)
DK (1) DK0678523T3 (de)
ES (1) ES2229206T3 (de)
PT (1) PT678523E (de)
WO (1) WO1994015969A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399067B1 (en) * 2000-04-28 2002-06-04 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
US7090843B1 (en) * 2000-11-28 2006-08-15 Seattle Genetics, Inc. Recombinant anti-CD30 antibodies and uses thereof
US7148038B2 (en) * 2001-10-16 2006-12-12 Raven Biotechnologies, Inc. Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof
JP4757493B2 (ja) * 2002-11-13 2011-08-24 レイベン バイオテクノロジーズ，インコーポレイティド 抗原ｐｉｐａおよびそれに結合する抗体
CN101213212A (zh) 2005-02-15 2008-07-02 西蒙有限公司 削弱hiv-1增殖的方法和组合物
KR101754433B1 (ko) * 2009-05-08 2017-07-05 백시넥스 인코포레이티드 항-ｃｄ100 항체 및 이의 사용 방법
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
CN102212133B (zh) * 2011-03-30 2013-01-16 中国医学科学院病原生物学研究所 人源HIV抗体的Fab片段及其编码基因与应用
CN102190726B (zh) * 2011-03-30 2013-03-27 中国医学科学院病原生物学研究所 一种人源HIV抗体的Fab片段及其编码基因与应用
HUE037408T2 (hu) 2011-06-10 2018-08-28 Univ Oregon Health & Science CMV glikoproteinek és rekombináns vektorok
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
EP2586461A1 (de) 2011-10-27 2013-05-01 Christopher L. Parks Von einem eingehüllten Virus abgeleitete Virenpartikel
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (de) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Verfahren zur Identifizierung neuartiger HIV-1-Immunogene
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US10174292B2 (en) 2015-03-20 2019-01-08 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
US9925258B2 (en) 2015-10-02 2018-03-27 International Aids Vaccine Initiative Replication-competent VSV-HIV Env vaccines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) * 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
JP2646007B2 (ja) * 1988-01-30 1997-08-25 財団法人 化学及血清療法研究所 抗ｈｉｖ抗体可変領域をコードする遺伝子断片およびこれらを用いて発現された抗ｈｉｖキメラ抗体ならびにその製法
JP2989862B2 (ja) * 1990-07-02 1999-12-13 財団法人化学及血清療法研究所 モノクローナル抗体

Also Published As

Publication number Publication date
DK0678523T3 (da) 2005-01-10
EP0678523A4 (de) 1998-08-05
WO1994015969A1 (en) 1994-07-21
EP0678523A1 (de) 1995-10-25
DE69333627T2 (de) 2005-09-22
CA2153165C (en) 2003-05-06
AU3267193A (en) 1994-08-15
PT678523E (pt) 2004-12-31
ATE276276T1 (de) 2004-10-15
ES2229206T3 (es) 2005-04-16
US5773247A (en) 1998-06-30
EP0678523B1 (de) 2004-09-15
AU671608B2 (en) 1996-09-05
CA2153165A1 (en) 1994-07-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee