DE69332087D1 - Verfahren zur erhöhung den stickoxidkonzentration im blut - Google Patents

Verfahren zur erhöhung den stickoxidkonzentration im blut

Info

Publication number
DE69332087D1
DE69332087D1 DE69332087T DE69332087T DE69332087D1 DE 69332087 D1 DE69332087 D1 DE 69332087D1 DE 69332087 T DE69332087 T DE 69332087T DE 69332087 T DE69332087 T DE 69332087T DE 69332087 D1 DE69332087 D1 DE 69332087D1
Authority
DE
Germany
Prior art keywords
blood
increasing
oxide concentration
nitrogen oxide
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69332087T
Other languages
English (en)
Other versions
DE69332087T2 (de
Inventor
Inc Etobicocke Vasogen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vasogen Ireland Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69332087D1 publication Critical patent/DE69332087D1/de
Publication of DE69332087T2 publication Critical patent/DE69332087T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0023—Agression treatment or altering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/32—Oxygenators without membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0216—Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
    • A61M2205/053—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy ultraviolet

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
DE69332087T 1992-02-07 1993-02-08 Verfahren zur erhöhung den stickoxidkonzentration im blut Expired - Fee Related DE69332087T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83279892A 1992-02-07 1992-02-07
US94132692A 1992-09-04 1992-09-04
PCT/GB1993/000259 WO1993015779A1 (en) 1992-02-07 1993-02-08 Method of increasing the concentration of nitric oxide in blood

Publications (2)

Publication Number Publication Date
DE69332087D1 true DE69332087D1 (de) 2002-08-08
DE69332087T2 DE69332087T2 (de) 2002-10-24

Family

ID=27125561

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69334101T Expired - Fee Related DE69334101T2 (de) 1992-02-07 1993-02-08 Verwendung von Blut mit erhöhter Stickoxidkonzentration zur Herstellung eines Medikaments
DE69332087T Expired - Fee Related DE69332087T2 (de) 1992-02-07 1993-02-08 Verfahren zur erhöhung den stickoxidkonzentration im blut

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69334101T Expired - Fee Related DE69334101T2 (de) 1992-02-07 1993-02-08 Verwendung von Blut mit erhöhter Stickoxidkonzentration zur Herstellung eines Medikaments

Country Status (13)

Country Link
US (1) US5834030A (de)
EP (2) EP1243278B1 (de)
JP (1) JP3989949B2 (de)
AT (2) ATE219953T1 (de)
AU (1) AU681999B2 (de)
CA (1) CA2129630C (de)
DE (2) DE69334101T2 (de)
DK (2) DK1243278T3 (de)
ES (2) ES2280454T3 (de)
HK (1) HK1053068B (de)
NZ (1) NZ249176A (de)
PT (2) PT1243278E (de)
WO (1) WO1993015779A1 (de)

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US6696092B2 (en) 1992-02-07 2004-02-24 Vasogen Ireland Limited Endothelial lining effects and treatment of vasospastic disorders
US5910316A (en) 1992-08-24 1999-06-08 The United States Of America, As Represented By The Department Of Health And Human Services Use of nitric oxide-releasing agents to treat impotency
AU760465B2 (en) * 1995-05-05 2003-05-15 Vasogen Ireland Limited Endothelial lining effects and treatment of vasospastic disorders
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JP4258908B2 (ja) * 1999-09-14 2009-04-30 株式会社ジェイ・エム・エス 人工肺装置
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CA2309424A1 (en) * 2000-05-25 2001-11-25 Vasogen Ireland Limited Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders
CA2414941C (en) 2000-08-11 2010-12-14 David R. Whitlock Compositions including ammonia oxidizing bacteria to increase production of nitric oxide and nitric oxide precursors and methods of using same
NL1015999C2 (nl) * 2000-08-23 2002-02-26 A J Van Liebergen Holding B V Inrichting voor het verwarmen van bloed of andere fysiologische vloeistoffen.
CA2327630A1 (en) * 2000-12-05 2002-06-05 Vasogen Ireland Limited Transforming growth factor regulation
US7122018B2 (en) 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
US6432077B1 (en) 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7335383B2 (en) * 2001-01-16 2008-02-26 The Regents Of The University Of Michigan Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood
US7128904B2 (en) * 2001-01-16 2006-10-31 The Regents Of The University Of Michigan Material containing metal ion ligand complex producing nitric oxide in contact with blood
JP4430867B2 (ja) * 2001-01-16 2010-03-10 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 基材／血液境界面で、ｉｎｓｉｔｕで、生体触媒により生じる、生体疑似的な（ｂｉｏｍｉｍｅｔｉｃ）一酸化窒素の生成
US7122208B2 (en) * 2001-04-06 2006-10-17 Vasogen Ireland Limited Compositions containing apoptotic entities
WO2003011359A2 (en) * 2001-08-01 2003-02-13 Monzyk Bruce F Artificial pulmonary capillary
US6472390B1 (en) * 2001-11-13 2002-10-29 Duke University Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure
WO2003057380A2 (en) * 2002-01-11 2003-07-17 Whitlock David R Compositions including ammonia oxidizing bacteria and methods of using same
CA2377442A1 (en) * 2002-03-20 2003-09-20 Thomas Ichim Increasing tumor oxygen content by administration of stressed cells
MXPA04009897A (es) * 2002-04-10 2004-12-07 Vasogen Ireland Ltd Aspectos electrocardiograficos del tratamiento de la insuficiencia cardiaca congestiva (chf).
US7531133B2 (en) 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
US20100316727A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of inflammatory disorders with ozone
US20100318014A1 (en) * 2003-07-31 2010-12-16 Latino Joseph S Treatment of acute ischemic brain stroke with ozone
US20050189302A1 (en) * 2003-07-31 2005-09-01 Latino Joseph S. Viral inactivation using ozone
US20050051497A1 (en) * 2003-07-31 2005-03-10 Latino Joseph S. Viral inactivation using ozone
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US7736494B2 (en) * 2003-07-31 2010-06-15 Acquisci, Inc. Ozone delivery system including a variable pitch gas-fluid contact device
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US8518457B2 (en) 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
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US20080181832A1 (en) * 2007-01-30 2008-07-31 Lih-Ren Shiue Pocket-size ozone generator
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ITMI20131667A1 (it) * 2013-10-09 2015-04-10 Ind Paolo Gobbi Frattini Metodo per pre-trattare le cellule ematiche prima della separazione.
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Also Published As

Publication number Publication date
PT680346E (pt) 2002-10-31
NZ249176A (en) 1996-11-26
EP0680346A1 (de) 1995-11-08
US5834030A (en) 1998-11-10
AU3506393A (en) 1993-09-03
ES2280454T3 (es) 2007-09-16
PT1243278E (pt) 2007-04-30
EP1243278A2 (de) 2002-09-25
EP0680346B1 (de) 2002-07-03
DK1243278T3 (da) 2007-05-07
DE69334101D1 (de) 2007-02-15
DE69334101T2 (de) 2007-10-04
ATE350046T1 (de) 2007-01-15
HK1053068A1 (en) 2003-10-10
ATE219953T1 (de) 2002-07-15
CA2129630C (en) 2003-09-23
AU681999B2 (en) 1997-09-18
CA2129630A1 (en) 1993-08-08
DE69332087T2 (de) 2002-10-24
JP3989949B2 (ja) 2007-10-10
WO1993015779A1 (en) 1993-08-19
HK1053068B (zh) 2007-03-30
ES2179828T3 (es) 2003-02-01
JPH07503722A (ja) 1995-04-20
EP1243278B1 (de) 2007-01-03
DK0680346T3 (da) 2002-10-28
EP1243278A3 (de) 2003-02-26

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: VASOGEN IRELAND LTD., SHANNON, COUNTY CLARE, IE

8381 Inventor (new situation)

Inventor name: BOLTON, ANTHONY E., SHEFFIELD S7 1NB, GB

Inventor name: BOLTON, ANTHONY E., SHEFFELD, GB

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee