DE69331970T2 - Teilchen mit gelatine-aminodextran-umhüllungen und verfahren zu ihrer herstellung - Google Patents

Teilchen mit gelatine-aminodextran-umhüllungen und verfahren zu ihrer herstellung

Info

Publication number
DE69331970T2
DE69331970T2 DE69331970T DE69331970T DE69331970T2 DE 69331970 T2 DE69331970 T2 DE 69331970T2 DE 69331970 T DE69331970 T DE 69331970T DE 69331970 T DE69331970 T DE 69331970T DE 69331970 T2 DE69331970 T2 DE 69331970T2
Authority
DE
Germany
Prior art keywords
aminodextran
gelatine
covers
particles
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331970T
Other languages
English (en)
Other versions
DE69331970D1 (de
Inventor
Olavi Siiman
Alexander Burshteyn
K Gupta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Coulter International Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69331970(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/968,158 external-priority patent/US5466609A/en
Application filed by Coulter International Corp filed Critical Coulter International Corp
Application granted granted Critical
Publication of DE69331970D1 publication Critical patent/DE69331970D1/de
Publication of DE69331970T2 publication Critical patent/DE69331970T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/30—Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/84—Polymer coating, e.g. gelatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69331970T 1992-10-15 1993-10-14 Teilchen mit gelatine-aminodextran-umhüllungen und verfahren zu ihrer herstellung Expired - Fee Related DE69331970T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96115792A 1992-10-15 1992-10-15
US07/968,158 US5466609A (en) 1990-10-31 1992-10-29 Biodegradable gelatin-aminodextran particle coatings of and processes for making same
PCT/US1993/009840 WO1994009368A1 (en) 1992-10-15 1993-10-14 Particles having gelatin-aminodextran coatings of and processes for making same

Publications (2)

Publication Number Publication Date
DE69331970D1 DE69331970D1 (de) 2002-07-04
DE69331970T2 true DE69331970T2 (de) 2002-12-19

Family

ID=27130420

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331970T Expired - Fee Related DE69331970T2 (de) 1992-10-15 1993-10-14 Teilchen mit gelatine-aminodextran-umhüllungen und verfahren zu ihrer herstellung

Country Status (6)

Country Link
EP (2) EP1213587A1 (de)
JP (2) JP3547437B2 (de)
AU (1) AU5360394A (de)
CA (1) CA2146964C (de)
DE (1) DE69331970T2 (de)
WO (1) WO1994009368A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994029724A1 (en) * 1993-06-11 1994-12-22 Coulter Corporation Anti-cd3 antibody-aminodextran conjugates for induction of t-cell activation and proliferation
ATE191086T1 (de) 1994-07-27 2000-04-15 Pilgrimm Herbert Superparamagnetische teilchen, verfahren zur herstellung und deren verwendung
DE19622886A1 (de) * 1996-06-07 1997-12-11 Boehringer Mannheim Gmbh Trockene Polymerbeadzubereitung
US6231982B1 (en) 1997-12-10 2001-05-15 Dade Behring Inc. Particle reagents having reduced matrix effects and containing an aldehyde-reactive functional group
FR2773416B1 (fr) * 1998-01-06 2000-02-11 Bio Merieux Particules magnetiques perfectionnees, leurs procedes d'obtention et leurs utilisations dans la separation de molecules
US6235540B1 (en) * 1999-03-30 2001-05-22 Coulter International Corp. Semiconductor nanoparticles for analysis of blood cell populations and methods of making same
US7179660B1 (en) 2000-03-06 2007-02-20 Dade Behring Marburg Gmbh Carriers coated with polysaccharides, their preparation and use
EP1348125A1 (de) * 2000-10-26 2003-10-01 Glaucus Proteomics B.V. Produkte mit biofunktioneller beschichtung
CA2463467A1 (en) * 2001-08-28 2003-05-01 Wen-Tien Chen Cell separation matrix
FR2832507B1 (fr) * 2001-11-20 2004-02-20 Stago Diagnostica Methode de detection d'analyte(s) a l'aide de particules magnetiques colloidales
WO2004097417A1 (en) * 2003-05-02 2004-11-11 Canon Kabushiki Kaisha Structured construct and producing method therefor
CA2538395A1 (en) * 2003-09-12 2005-03-24 Bankruptcy Estate Of Ferx, Inc. Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents
US20090014682A1 (en) 2005-05-20 2009-01-15 Jsr Corporation Carrier Polymer Particle, Process for Producing the Same, Magnetic Particle for Specific Trapping, and Process for Producing the Same
JP2009517463A (ja) * 2005-12-02 2009-04-30 インダストリー−アカデミック コーペレイション ファウンデイション， ヨンセイ ユニバーシティ 水溶性マンガン酸化物ナノ粒子を含むｍｒｉ造影剤
IES20050816A2 (en) * 2005-12-06 2007-05-16 Trinity Res Ltd A method for preparing microbeads for use in an assay for determining the presence of antibodies to human immunodeficiency virus in a sample
JP5364310B2 (ja) * 2008-07-14 2013-12-11 アルフレッサファーマ株式会社 反応性物質が結合した微小粒子の安定化方法および該微小粒子含有試薬
EP2839286B1 (de) * 2012-04-18 2018-02-28 Siemens Healthcare Diagnostics Inc. Verbindungen und verfahren zur herstellung von konjugatreagenzien
WO2014034884A1 (ja) * 2012-08-31 2014-03-06 国立大学法人北陸先端科学技術大学院大学 凍結保存可能な細胞足場材料
JP2018019686A (ja) * 2016-07-20 2018-02-08 コニカミノルタ株式会社 ゼラチン粒子、ゼラチン粒子の製造方法、ゼラチン粒子内包細胞、ゼラチン粒子内包細胞の製造方法、および細胞構造体
JP7352885B2 (ja) * 2018-12-17 2023-09-29 パナソニックＩｐマネジメント株式会社 修飾粒子の製造方法
CN111185301B (zh) * 2020-01-10 2022-09-30 江苏梵爵机械制造有限公司 一种干式环保选矿系统及选矿方法
EP4136983A4 (de) * 2020-04-16 2024-01-24 Mitsubishi Corporation Life Sciences Limited Dextranbeschichtete zusammensetzung enthaltender eigenschaftsverbesserer für nahrungsmittel

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5814253B2 (ja) * 1974-04-10 1983-03-18 カンザキセイシ カブシキガイシヤ ビシヨウカプセルノ セイゾウホウホウ
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
NO155316C (no) * 1982-04-23 1987-03-11 Sintef Fremgangsmaate for fremstilling av magnetiske polymerpartikler.
US4582622A (en) * 1984-10-12 1986-04-15 Fujirebio Kabushiki Kaisha Magnetic particulate for immobilization of biological protein and process of producing the same
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US4891324A (en) * 1987-01-07 1990-01-02 Syntex (U.S.A.) Inc. Particle with luminescer for assays
JPH05504481A (ja) * 1990-02-20 1993-07-15 クールター　コーポレイション 改良された抗体―酵素直接接合体及びその製造方法
US5062991A (en) * 1990-06-04 1991-11-05 Coulter Corporation In situ use of gelatin in the preparation of uniform ferrite particles
US5169754A (en) * 1990-10-31 1992-12-08 Coulter Corporation Biodegradable particle coatings having a protein covalently immobilized by means of a crosslinking agent and processes for making same
US5248772A (en) * 1992-01-29 1993-09-28 Coulter Corporation Formation of colloidal metal dispersions using aminodextrans as reductants and protective agents

Also Published As

Publication number Publication date
JPH08502443A (ja) 1996-03-19
CA2146964C (en) 2005-11-29
EP0665955A1 (de) 1995-08-09
CA2146964A1 (en) 1994-04-28
AU5360394A (en) 1994-05-09
EP1213587A1 (de) 2002-06-12
EP0665955A4 (de) 1998-12-09
JP2004003991A (ja) 2004-01-08
EP0665955B1 (de) 2002-05-29
JP3547437B2 (ja) 2004-07-28
WO1994009368A1 (en) 1994-04-28
DE69331970D1 (de) 2002-07-04

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee