DE69330562D1 - Biotherapeutische mikrosphären beschichtet mit zellen - Google Patents

Biotherapeutische mikrosphären beschichtet mit zellen

Info

Publication number
DE69330562D1
DE69330562D1 DE69330562T DE69330562T DE69330562D1 DE 69330562 D1 DE69330562 D1 DE 69330562D1 DE 69330562 T DE69330562 T DE 69330562T DE 69330562 T DE69330562 T DE 69330562T DE 69330562 D1 DE69330562 D1 DE 69330562D1
Authority
DE
Germany
Prior art keywords
pct
skin
date nov
microspheres
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69330562T
Other languages
English (en)
Other versions
DE69330562T2 (de
Inventor
W Armstrong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
Original Assignee
National Research Council of Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council of Canada filed Critical National Research Council of Canada
Application granted granted Critical
Publication of DE69330562D1 publication Critical patent/DE69330562D1/de
Publication of DE69330562T2 publication Critical patent/DE69330562T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/985—Skin or skin outgrowth, e.g. hair, nails
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2531/00—Microcarriers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Birds (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
DE69330562T 1992-05-18 1993-04-23 Biotherapeutische mikrosphären beschichtet mit zellen Expired - Fee Related DE69330562T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929210574A GB9210574D0 (en) 1992-05-18 1992-05-18 Biotherapeutic cell-coated microspheres for wound/burn and prothesis implant applications
PCT/CA1993/000187 WO1993023088A1 (en) 1992-05-18 1993-04-23 Biotherapeutic cell-coated microspheres

Publications (2)

Publication Number Publication Date
DE69330562D1 true DE69330562D1 (de) 2001-09-13
DE69330562T2 DE69330562T2 (de) 2002-05-29

Family

ID=10715656

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69330562T Expired - Fee Related DE69330562T2 (de) 1992-05-18 1993-04-23 Biotherapeutische mikrosphären beschichtet mit zellen

Country Status (16)

Country Link
US (1) US5830507A (de)
EP (1) EP0641223B1 (de)
JP (1) JP2820796B2 (de)
KR (1) KR950701533A (de)
AT (1) ATE203916T1 (de)
BR (1) BR9306375A (de)
CA (1) CA2135999C (de)
DE (1) DE69330562T2 (de)
DK (1) DK0641223T3 (de)
ES (1) ES2161229T3 (de)
GB (1) GB9210574D0 (de)
GR (1) GR3036741T3 (de)
NZ (1) NZ252661A (de)
PT (1) PT641223E (de)
RU (1) RU2104039C1 (de)
WO (1) WO1993023088A1 (de)

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US5654267A (en) * 1988-12-20 1997-08-05 La Jolla Cancer Research Center Cooperative combinations of ligands contained within a matrix
IL115728A0 (en) * 1994-10-25 1996-01-19 Boehringer Mannheim Gmbh Biomaterial containing epithelial cells and use thereof as a transplant
IL118376A0 (en) * 1996-05-22 1996-09-12 Univ Ben Gurion Polysaccharide sponges for cell culture and transplantation
US5972332A (en) * 1997-04-16 1999-10-26 The Regents Of The University Of Michigan Wound treatment with keratinocytes on a solid support enclosed in a porous material
US20020037566A1 (en) * 1997-04-16 2002-03-28 Rees Riley S. Cell-coated supports
US5861149A (en) * 1997-06-04 1999-01-19 Polyheal Ltd. Methods for wound treatment
WO1999021963A1 (de) * 1997-10-25 1999-05-06 Roche Diagnostics Gmbh Autodegradable microcarriers and their use
US6378527B1 (en) * 1998-04-08 2002-04-30 Chondros, Inc. Cell-culture and polymer constructs
BR9909717A (pt) * 1998-04-17 2000-12-26 Angiogenix Inc Fatores angiogênicos terapêuticos e métodos para seu uso
IL136583A0 (en) * 1998-10-23 2001-06-14 Polyheal Ltd Compositions of microspheres for wound healing
DE19937102A1 (de) * 1999-08-06 2001-02-15 Universitaetsklinikum Freiburg Gewebeersatz und Verfahren zu seiner Herstellung
US7056503B2 (en) * 1999-08-19 2006-06-06 Regents Of The University Of Michigan Enclosures housing cell-coated supports for treating tumors
DE19949290A1 (de) * 1999-10-12 2001-04-26 Albrecht Bettermann Partikuläres Konstrukt zur Verwendung in der Transplantationsmedizin
KR20010110945A (ko) 2000-06-09 2001-12-15 김정용 음경 확대 방법
US6719970B1 (en) * 2000-07-10 2004-04-13 Alkermes Controlled Therapeutics, Inc. Method of generating cartilage
US20060258562A1 (en) * 2000-07-31 2006-11-16 Healor Ltd. Methods and pharmaceutical compositions for healing wounds
US20030148924A1 (en) * 2002-07-09 2003-08-07 Tamar Tennenbaum Methods and pharmaceutical compositions of healing wounds
US20100129332A1 (en) * 2000-07-31 2010-05-27 Tamar Tennenbaum Methods and pharmaceutical compositions for healing wounds
US20040037828A1 (en) * 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
JP2002281964A (ja) * 2000-12-26 2002-10-02 Sanyo Chem Ind Ltd 細胞生産方法
AUPR289601A0 (en) * 2001-02-05 2001-03-01 Commonwealth Scientific And Industrial Research Organisation Method of tissue repair
US20050129776A1 (en) * 2002-05-03 2005-06-16 Inserm Microparticles supporting cells and active substances
FR2839260B1 (fr) * 2002-05-03 2005-02-25 Inst Nat Sante Rech Med Microparticules a base d'un materiau bicompatible et biodegradable, supportant des cellules et des substances biologiquement actives
US7402323B2 (en) * 2002-08-21 2008-07-22 Akpharma, Inc. Compositions and methods for treating skin conditions
EP2340856B2 (de) * 2003-05-24 2017-11-15 La Prairie Group AG Kosmetische oder dermatologische Zubereitung umfassend eine Nährmedienphase
ES2291890T3 (es) * 2003-06-23 2008-03-01 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Procedimiento para la diferenciacion de celulas madre en celulas que producen una hormona pancreatica.
WO2005013885A2 (en) * 2003-08-07 2005-02-17 Healor Ltd. Pharmaceutical compositions and methods for accelerating wound healing
KR20060109908A (ko) * 2003-10-20 2006-10-23 가부시키가이샤 제이.에무.에스 세포 취급 장치, 조직 재생용 조성물 및 조직 재생 방법
WO2007026356A2 (en) 2005-08-29 2007-03-08 Healor Ltd. Methods and compositions for prevention and treatment of diabetic and aged skin
WO2008073614A2 (en) * 2006-11-02 2008-06-19 Akpharma Inc. Composition and method for enhancing skin cell growth, proliferation and repair
KR100805208B1 (ko) 2007-03-27 2008-02-21 주식회사 펩트론 엑센딘 함유 서방성 제제 조성물, 엑센딘 함유 서방성미립구 및 이의 제조 방법
US20100255070A1 (en) * 2007-05-22 2010-10-07 Prelief Inc. Compositions and methods for preventing, minimizing and healing skin irritation and trauma
KR20100040912A (ko) * 2007-07-30 2010-04-21 힐로 리미티드 약제학적 조성물 및 관련 방법
US20100278798A1 (en) * 2007-09-27 2010-11-04 The Trustees Of Columbia University In The City Of New York Methods and systems for forming biocompatible materials
WO2009086535A2 (en) * 2007-12-27 2009-07-09 The Trustees Of Columbia University In The City Of New York Systems and methods for forming patterned extracellular matrix materials
CN102056619A (zh) 2008-04-18 2011-05-11 科尔普兰特有限公司 产生和使用原胶原的方法
CN102066904B (zh) 2008-06-13 2015-07-15 株式会社资生堂 皮肤代替膜、模具以及皮肤外用剂的评价方法
EA014044B1 (ru) * 2008-07-09 2010-08-30 Общество С Ограниченной Ответственностью "Аква-Альянс" Наносомальная лекарственная форма препарата пролонгированного действия для лечения гепатита с (варианты)
JP5767239B2 (ja) * 2009-12-04 2015-08-19 マグレ アクティエボラーグ 内因性荷電リガンドを有する加水分解澱粉の微小球
WO2011083483A2 (en) 2010-01-11 2011-07-14 Healor Ltd. Method for treatment of inflammatory disease and disorder
JP5241764B2 (ja) * 2010-03-31 2013-07-17 テルモ株式会社 生体適合性材料の評価方法
RU2616866C1 (ru) * 2015-12-31 2017-04-18 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Биорезорбируемый микроноситель для доставки клеток в область заживления и регенерации ран
RU2658707C1 (ru) * 2016-12-28 2018-06-22 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ восстановления кожного покрова
RU2644633C1 (ru) * 2016-12-28 2018-02-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Способ восстановления кожного покрова
CN110960513A (zh) * 2019-11-29 2020-04-07 苏州瑞微生物科技有限公司 一种微球阵列及其制备方法和用途
CN113201481B (zh) * 2021-04-19 2023-10-13 清华大学深圳国际研究生院 皮肤微球及其制备方法和应用

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Also Published As

Publication number Publication date
DK0641223T3 (da) 2001-10-01
GR3036741T3 (en) 2001-12-31
CA2135999A1 (en) 1993-11-25
ATE203916T1 (de) 2001-08-15
DE69330562T2 (de) 2002-05-29
US5830507A (en) 1998-11-03
GB9210574D0 (en) 1992-07-01
CA2135999C (en) 1999-07-13
AU4257993A (en) 1993-12-13
EP0641223A1 (de) 1995-03-08
EP0641223B1 (de) 2001-08-08
WO1993023088A1 (en) 1993-11-25
BR9306375A (pt) 1997-03-04
AU668959B2 (en) 1996-05-23
RU2104039C1 (ru) 1998-02-10
ES2161229T3 (es) 2001-12-01
RU94046192A (ru) 1996-10-10
KR950701533A (ko) 1995-04-28
KR100381207B1 (de) 2003-10-23
JP2820796B2 (ja) 1998-11-05
PT641223E (pt) 2001-12-28
NZ252661A (en) 1996-09-25
JPH07507063A (ja) 1995-08-03

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee