DE69322250T2 - 3-hydroxypyridin-4-on-derivate als chelatbildner - Google Patents
3-hydroxypyridin-4-on-derivate als chelatbildnerInfo
- Publication number
- DE69322250T2 DE69322250T2 DE69322250T DE69322250T DE69322250T2 DE 69322250 T2 DE69322250 T2 DE 69322250T2 DE 69322250 T DE69322250 T DE 69322250T DE 69322250 T DE69322250 T DE 69322250T DE 69322250 T2 DE69322250 T2 DE 69322250T2
- Authority
- DE
- Germany
- Prior art keywords
- ethyl
- pct
- methylpropionyloxy
- alpha
- hydroxypyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929217099A GB9217099D0 (en) | 1992-08-12 | 1992-08-12 | Pharmaceutical compositions |
PCT/GB1993/001007 WO1994004498A1 (en) | 1992-08-12 | 1993-05-18 | 3-hydroxypyridin-4-one derivatives as chelating agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69322250D1 DE69322250D1 (de) | 1999-01-07 |
DE69322250T2 true DE69322250T2 (de) | 1999-05-20 |
Family
ID=10720221
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69322250T Expired - Fee Related DE69322250T2 (de) | 1992-08-12 | 1993-05-18 | 3-hydroxypyridin-4-on-derivate als chelatbildner |
Country Status (10)
Country | Link |
---|---|
US (1) | US5480894A (de) |
EP (1) | EP0619808B1 (de) |
JP (1) | JPH07500120A (de) |
AT (1) | ATE173726T1 (de) |
CA (1) | CA2119020C (de) |
DE (1) | DE69322250T2 (de) |
ES (1) | ES2124307T3 (de) |
GB (2) | GB9217099D0 (de) |
WO (1) | WO1994004498A1 (de) |
ZA (1) | ZA935084B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2230564T3 (es) | 1995-06-10 | 2005-05-01 | Vitra Pharmaceuticals Ltd. | Compuestos ferricos, composiciones, metodos de fabricacion de estos y sus utilizacioneds. |
DE59611243D1 (de) * | 1995-09-29 | 2005-08-11 | Novartis Ag | Hydroxypyridinone |
US6767741B1 (en) | 1999-08-27 | 2004-07-27 | Invitrogen Corporation | Metal binding compounds and their use in cell culture medium compositions |
IL135884A (en) * | 2000-04-30 | 2005-08-31 | Yissum Res Dev Co | Method for measuring non-transferrin bound iron |
US7135196B2 (en) | 2000-09-19 | 2006-11-14 | Vitra Pharmaceuticals Limited | Iron compositions |
TW583310B (en) * | 2000-12-22 | 2004-04-11 | Ashland Inc | Composition comprising an oxidizing and complexing compound |
US6426418B1 (en) | 2001-11-02 | 2002-07-30 | Apotex, Inc. | Processes for the manufacturing of 3-hydroxy-N,1,6-trialkyl-4-oxo-1,4-dihydropyridine-2-carboxamide |
ATE373644T1 (de) | 2002-02-05 | 2007-10-15 | Bristol Myers Squibb Co | N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika |
GB0211500D0 (en) | 2002-05-18 | 2002-06-26 | Vitra Pharmaceuticals Ltd | Method of forming iron hydroxypyrone compounds |
EP2295980A1 (de) | 2002-10-30 | 2011-03-16 | Yissum Research Development Company, of The Hebrew University of Jerusalem | Moleküle und diese verwendende Verfahren zur Messung von nicht-transferringebundenem Eisen |
US7707255B2 (en) | 2003-07-01 | 2010-04-27 | Microsoft Corporation | Automatic grouping of electronic mail |
NZ529657A (en) * | 2003-11-20 | 2004-07-30 | Apotex Inc | Iron chelating cycloalkyl derivatives of 3-hydroxy-4-pyridinones |
CA2488034C (en) * | 2004-11-19 | 2009-10-06 | Apotex Inc. | Process for the manufacture of 3-hydroxy-n-alkyl-1-cycloalkyl-6-alkyl-4-oxo-1,4-dihydropyridine-2-carboxamide and its related analogues |
US9588781B2 (en) | 2008-03-31 | 2017-03-07 | Microsoft Technology Licensing, Llc | Associating command surfaces with multiple active components |
GB201007209D0 (en) | 2010-04-29 | 2010-06-16 | King S College London | Compound |
WO2012137202A1 (en) | 2011-04-05 | 2012-10-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci) |
DE102012007558A1 (de) | 2012-04-14 | 2013-10-17 | Alf Hammes | Gabe substituierter bis-aryl-harnstoffderivate zur behandlung von anämien |
GB201215675D0 (en) | 2012-09-03 | 2012-10-17 | Univ Exeter | Compound |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1074038B (it) * | 1976-08-05 | 1985-04-17 | Simes | Esteri della epinina |
GB8308055D0 (en) * | 1983-03-24 | 1983-05-05 | Hider R C | Pharmaceutical compositions |
GB8308054D0 (en) * | 1983-03-24 | 1983-05-05 | Hider R C | Pharmaceutical compositions |
EP0305646B1 (de) * | 1983-03-24 | 1996-11-13 | Btg International Limited | 3-Hydroxypyrid-4-one und pharmazeutische Zusammensetzungen |
US4908371A (en) * | 1987-11-10 | 1990-03-13 | Ciba-Geigy Corporation | Esterified hydroxy dihydropyridinones for treating diseases associated with trivalent metal ion overload |
WO1989009211A1 (en) * | 1988-03-31 | 1989-10-05 | The Royal Free Hospital School Of Medicine | Process for producing pyrid-4-ones |
GB8910521D0 (en) * | 1989-05-08 | 1989-06-21 | Nat Res Dev | The stabilization of organic compounds |
GB9100465D0 (en) * | 1991-01-09 | 1991-02-20 | Hider Robert C | Pharmaceutical compositions |
GB9209078D0 (en) * | 1992-04-27 | 1992-06-10 | Hider Robert C | Pharmaceutical compositions |
-
1992
- 1992-08-12 GB GB929217099A patent/GB9217099D0/en active Pending
-
1993
- 1993-05-18 CA CA002119020A patent/CA2119020C/en not_active Expired - Fee Related
- 1993-05-18 EP EP93910215A patent/EP0619808B1/de not_active Expired - Lifetime
- 1993-05-18 DE DE69322250T patent/DE69322250T2/de not_active Expired - Fee Related
- 1993-05-18 ES ES93910215T patent/ES2124307T3/es not_active Expired - Lifetime
- 1993-05-18 JP JP6505976A patent/JPH07500120A/ja active Pending
- 1993-05-18 AT AT93910215T patent/ATE173726T1/de not_active IP Right Cessation
- 1993-05-18 US US08/204,202 patent/US5480894A/en not_active Expired - Fee Related
- 1993-05-18 WO PCT/GB1993/001007 patent/WO1994004498A1/en active IP Right Grant
- 1993-07-01 GB GB9313557A patent/GB2269589B/en not_active Revoked
- 1993-07-14 ZA ZA935084A patent/ZA935084B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE69322250D1 (de) | 1999-01-07 |
CA2119020A1 (en) | 1994-03-03 |
GB2269589B (en) | 1996-06-26 |
ES2124307T3 (es) | 1999-02-01 |
GB9313557D0 (en) | 1993-08-18 |
GB9217099D0 (en) | 1992-09-23 |
JPH07500120A (ja) | 1995-01-05 |
ZA935084B (en) | 1995-01-16 |
EP0619808A1 (de) | 1994-10-19 |
WO1994004498A1 (en) | 1994-03-03 |
US5480894A (en) | 1996-01-02 |
GB2269589A (en) | 1994-02-16 |
CA2119020C (en) | 2003-12-16 |
EP0619808B1 (de) | 1998-11-25 |
ATE173726T1 (de) | 1998-12-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |