DE69316138D1 - Pharmazeutische Zubereitung mit Polymyxin-Trimethoprim und einem anti-inflammatorischen Stoff zur ophthalmischen Verwendung und zur topischen Anwendung am Ohr - Google Patents

Pharmazeutische Zubereitung mit Polymyxin-Trimethoprim und einem anti-inflammatorischen Stoff zur ophthalmischen Verwendung und zur topischen Anwendung am Ohr

Info

Publication number
DE69316138D1
DE69316138D1 DE69316138T DE69316138T DE69316138D1 DE 69316138 D1 DE69316138 D1 DE 69316138D1 DE 69316138 T DE69316138 T DE 69316138T DE 69316138 T DE69316138 T DE 69316138T DE 69316138 D1 DE69316138 D1 DE 69316138D1
Authority
DE
Germany
Prior art keywords
trimethoprim
polymyxin
ear
pharmaceutical preparation
ophthalmic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69316138T
Other languages
English (en)
Inventor
Michael Van Wie Bergamini
Sanjurjo Teresa Borras
Colomer Jordi Coll
Paino Ricardo Notivol
Laguens Carmen Oros
Mas Jose Alberto Vallet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Cusi SA
Original Assignee
Laboratorios Cusi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Cusi SA filed Critical Laboratorios Cusi SA
Application granted granted Critical
Publication of DE69316138D1 publication Critical patent/DE69316138D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69316138T 1992-10-07 1993-10-07 Pharmazeutische Zubereitung mit Polymyxin-Trimethoprim und einem anti-inflammatorischen Stoff zur ophthalmischen Verwendung und zur topischen Anwendung am Ohr Expired - Lifetime DE69316138D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09201979A ES2079994B1 (es) 1992-10-07 1992-10-07 Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.

Publications (1)

Publication Number Publication Date
DE69316138D1 true DE69316138D1 (de) 1998-02-12

Family

ID=8278322

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69316138T Expired - Lifetime DE69316138D1 (de) 1992-10-07 1993-10-07 Pharmazeutische Zubereitung mit Polymyxin-Trimethoprim und einem anti-inflammatorischen Stoff zur ophthalmischen Verwendung und zur topischen Anwendung am Ohr

Country Status (6)

Country Link
US (1) US5679665A (de)
EP (1) EP0592348B1 (de)
JP (1) JPH06239762A (de)
AT (1) ATE161728T1 (de)
DE (1) DE69316138D1 (de)
ES (1) ES2079994B1 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372716B1 (en) * 1994-04-26 2002-04-16 Genetics Institute, Inc. Formulations for factor IX
ES2079320B1 (es) * 1994-05-17 1996-10-16 Cusi Lab Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones.
AU3609795A (en) * 1994-10-10 1996-05-02 Novartis Ag Ophthalmic and aural compositions containing diclofenac potassium
JP3672569B2 (ja) * 1995-01-20 2005-07-20 わかもと製薬株式会社 抗炎症点眼剤
US5869079A (en) * 1995-06-02 1999-02-09 Oculex Pharmaceuticals, Inc. Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
DE69837664T2 (de) * 1997-05-14 2008-01-03 Senju Pharmaceutical Co., Ltd. Wässrige suspensionspräparationen mit exzellenter redispersibilität
DE19729879C2 (de) * 1997-07-11 1999-07-08 Mann Gerhard Chem Pharm Fab Lagerstabile ophthalmische Zusammensetzungen, umfassend Diclofenac und Ofloxacin
EP0938896A1 (de) 1998-01-15 1999-09-01 Novartis AG In Autoklaven behandelbare pharmazeutische Zusammensetzungen mit Komplexbildner
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6509327B1 (en) * 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
US6528488B2 (en) * 1999-01-08 2003-03-04 Demegen, Inc. Method for treating cystic fibrosis
CA2362481C (en) * 1999-03-03 2008-11-04 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
US7056893B2 (en) * 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
WO2000064528A1 (en) 1999-04-28 2000-11-02 Situs Corporation Drug delivery system
US7064132B2 (en) * 1999-11-28 2006-06-20 Scientific Development And Research, Inc. Composition and method for treatment of otitis external
US6156294A (en) 1999-11-28 2000-12-05 Scientific Development And Research, Inc. Composition and method for treatment of otitis media
WO2002015878A1 (en) * 2000-08-25 2002-02-28 Senju Pharmaceutical Co., Ltd. Aqueous suspension preparations
WO2002078681A2 (en) * 2001-04-02 2002-10-10 Alcon, Inc. Method of treating ocular inflammatory and angiogenesis-related disorders using an amide derivative of flubiprofen or ketorolac
US6835536B2 (en) 2001-08-21 2004-12-28 Micrologix Biotech Inc. Antimicrobial cationic peptides and formulations thereof
US8933029B2 (en) 2001-08-24 2015-01-13 Carrus Capital Corporation Antimicrobial and anti-inflammatory peptides
JP2006510657A (ja) * 2002-12-06 2006-03-30 アライバ ファーマシューティカルズ，インコーポレイティド 中耳炎の処置のための方法および組成物
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
AU2003303191A1 (en) * 2002-12-20 2004-07-14 Deepak Bahri Composition comprising diclofenac for treating otic pain and inflammation
US20050147584A1 (en) * 2004-01-05 2005-07-07 Allergan, Inc. Compositions and methods comprising memantine and polyanionic polymers
US20050031652A1 (en) * 2003-02-25 2005-02-10 Allergan, Inc. Compositions and methods comprising memantine and polyanionic polymers
US20050009931A1 (en) * 2003-03-20 2005-01-13 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20050004098A1 (en) * 2003-03-20 2005-01-06 Britten Nancy Jean Dispersible formulation of an anti-inflammatory agent
DK1608407T3 (da) * 2003-03-20 2006-12-04 Pharmacia Corp Dispergébar formulering af et antiinflammatorisk middel
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20040204471A1 (en) * 2003-03-20 2004-10-14 Pharmacia Corporation Treatment and prevention of otic disorders with Cox-2 inhibitors alone or in combination with otic agents
US8940321B2 (en) 2003-12-12 2015-01-27 Otic Pharma Ltd. Compositions for treatment of ear disorders and methods of use thereof
CA2548892C (en) * 2003-12-12 2015-10-27 Eran Eilat Compositions for treatment of ear disorders and methods of use thereof
US20050277698A1 (en) * 2004-01-05 2005-12-15 Hughes Patrick M Memantine delivery to the back of the eye
MXPA06008648A (es) * 2004-01-30 2006-09-04 Pfizer Prod Inc Composiciones farmaceuticas de antagonistas del receptor de neuroquinina y ciclodextrina y metodos para una tolerancia mejorada en el sitio de inyeccion.
ES2245611B1 (es) * 2004-06-29 2007-03-16 Laboratorio Reig Jofre, S.A. Composicion farmaceutica para uso ototopico.
TWI393567B (zh) 2005-03-31 2013-04-21 Bausch & Lomb 治療乾眼之組合物及相關之製造方法及使用方法
TW200722109A (en) * 2005-03-31 2007-06-16 Bausch & Lomb Polysaccharide and polyol composition for treating dry eye and related methods of manufacture and methods of use
US8552042B2 (en) * 2006-05-12 2013-10-08 Christian Noe Use of combination preparations comprising antifungal agents
WO2008057360A1 (en) * 2006-11-02 2008-05-15 Riolan Technologies, Inc. Methods of treating an ocular allergy with low dose dexamethasone
EP2089035A1 (de) * 2006-11-02 2009-08-19 Riolan Technologies, Inc. Verfahren zur behandlung von blepharitis
WO2008075522A1 (ja) * 2006-12-21 2008-06-26 Nihon Medi-Physics Co., Ltd. 放射性画像診断剤
WO2008085913A1 (en) * 2007-01-04 2008-07-17 Rib-X Pharmaceuticals, Inc. Methods for treating, preventing, or reducing the risk of opthalmic, otic, and nasal infections
US20100249418A1 (en) * 2007-10-24 2010-09-30 Nihon Medi-Physics Co., Ltd. Novel compound having affinity for amyloid
MX2010004953A (es) * 2007-11-27 2010-08-10 Alcon Res Ltd Formulaciones de solucion oftalmica u otica topicas que contienen clorihidrato de moxifloxacina y fosfato de dexametasona.
US8300252B2 (en) * 2008-06-18 2012-10-30 Livescribe, Inc. Managing objects with varying and repeated printed positioning information
TWI580441B (zh) 2008-09-19 2017-05-01 愛爾康研究有限公司 穩定的藥學次微米懸浮液及其形成方法
JP2012506435A (ja) * 2008-10-21 2012-03-15 ギリアード サイエンシーズ， インコーポレイテッド 眼の感染症、耳の感染症、および皮膚の感染症の処置および予防のためのホスホマイシン／トブラマイシンの組み合わせ
CN107530397A (zh) * 2014-12-18 2018-01-02 赫尔普百治疗有限公司 新型组合和用途
WO2017024029A1 (en) * 2015-08-03 2017-02-09 Synergistic Therapeutics, Llc Sexual dysfunction therapeutic gel
JP7072898B2 (ja) * 2016-08-16 2022-05-23 ユニバーシティ オブ ロチェスター ポリミキシンｂ／トリメトプリム系の治療薬を含有する医薬組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7416636A (nl) * 1973-12-27 1975-07-01 Wellcome Found Farmaceutisch preparaat.
AU542560B2 (en) * 1980-03-21 1985-02-28 Wellcome Foundation Limited, The Stabilised ophthalmic solution
JPS5732218A (en) * 1980-07-29 1982-02-20 Syntex Corp Pharmaceutical composition for capillary vessel diseases
IT1229075B (it) * 1985-04-05 1991-07-17 Fidia Farmaceutici Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
JPS60184013A (ja) * 1984-03-01 1985-09-19 Yoshitomi Pharmaceut Ind Ltd 点眼剤
JPH0660101B2 (ja) * 1984-11-27 1994-08-10 参天製薬株式会社 クロベタゾン−１７−ブチレ−トの水性製剤
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
AU610175B2 (en) * 1988-05-25 1991-05-16 Biogal Gyogyszergyar Pharmaceutical composition comprising a compound containing sulfhydryl group(s) for the treatment of otitis
IL95942A0 (en) * 1989-10-13 1991-07-18 Syntex Inc Collagen-containing ophthalmic formulation

Also Published As

Publication number Publication date
ES2079994A1 (es) 1996-01-16
ATE161728T1 (de) 1998-01-15
JPH06239762A (ja) 1994-08-30
EP0592348A1 (de) 1994-04-13
EP0592348B1 (de) 1998-01-07
US5679665A (en) 1997-10-21
ES2079994B1 (es) 1996-08-01

Similar Documents

Publication Publication Date Title
DE69316138D1 (de) Pharmazeutische Zubereitung mit Polymyxin-Trimethoprim und einem anti-inflammatorischen Stoff zur ophthalmischen Verwendung und zur topischen Anwendung am Ohr
CA2031880A1 (en) Combined anti-inflammatory agent
AU653415B2 (en) Method of treating ocular inflammation
AU3113693A (en) Ophthalmic pharmaceutical composition containing n-acetyl-cysteine and polyvinylalcohol
DE69739656D1 (de) 1 inhibitor und hyaluronan als polymer mit verzögerter wirkstofffreigabe
KR950002785A (ko) 골량을 증가시키기 위한 부갑상선 호르몬 및 랄옥시펜
EP0142426A3 (de) Ophthalmische Zusammensetzung enthaltend Norfloxacin und verwandte Antibiotika
AU6029096A (en) Compositions and methods for topical administration of pharm aceutically active agents
FR2710265B1 (fr) Composition pharmaceutique bioadhésive pour la libération contrôlée de principes actifs.
TR199801180T2 (xx) Aneljestik etkiye sahip yeni bile�ikler.
BR9807234A (pt) Composição farmacêutica
AU1809495A (en) Composition and method for preventing and treating inflammation with immunoglobulin a
HK1000283A1 (en) New derivatives of non-steroidal anti-inflammatory anaggesic and/or antipyretic substances their use and pharmaceutical formulations containg them
WO2000023057A3 (en) Atypical antiphsychotic in combination with acetylcholinesterase inhibitor for improving cognition
IT1252692B (it) Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi
MX9603596A (es) Perfluoropolieteres o composiciones de los mismos para prevencion y tratamiento de infecciones virales topicas.
RU94031161A (ru) Фармацевтическая композиция и способ ее получения, способ лечения нарушений, развивающихся вследствие нейродегенеративных процессов
AU3080892A (en) Immediate-effect ibuprofen-containing medicament and its use
ES2065846A1 (es) Formulacion farmaceutica a base de un agente antiinflamatorio esteroidico o no esteroidico y un antibiotico pertenciente al grupo de los inhibidores de la adn girasa para su utilizacion topica oftalmica.
ATE226084T1 (de) Wundheilung und behandlung von fibrose
ES2078175A1 (es) Formulacion farmaceutica conteniendo clobetasona y tobramicina y sus aplicaciones.
IT1240683B (it) Composizione farmaceutica contenente egf
SE9403389D0 (sv) Pharmaceutical composition containing derivattves of sex hormones
ITRM910730A1 (it) Composizioni farmaceutiche, per uso topico, contenenti "scavengers" di radicali liberi dell'ossigeno e antibatterici, indicate nella terapia dei tessuti superficiali.
BR9508021A (pt) Composição farmacêutica para o tratamento de distúrbios esquizofrênicos, uso de um agente imunossupressor, e, processo de tratamento de um paciente esquizofrênico

Legal Events

Date Code Title Description
8332 No legal effect for de