DE69306513D1 - Neue kardioaktive Zyklopentaperhydrophenanthrene-17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta Derivate, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon - Google Patents
Neue kardioaktive Zyklopentaperhydrophenanthrene-17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta Derivate, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davonInfo
- Publication number
- DE69306513D1 DE69306513D1 DE69306513T DE69306513T DE69306513D1 DE 69306513 D1 DE69306513 D1 DE 69306513D1 DE 69306513 T DE69306513 T DE 69306513T DE 69306513 T DE69306513 T DE 69306513T DE 69306513 D1 DE69306513 D1 DE 69306513D1
- Authority
- DE
- Germany
- Prior art keywords
- beta
- alkoxy
- aryl
- alpha
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69306513T DE69306513T2 (de) | 1992-09-29 | 1993-09-22 | Neue kardioaktive Zyklopentaperhydrophenanthrene-17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta Derivate, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4232656A DE4232656C2 (de) | 1992-09-29 | 1992-09-29 | Cyclopentanperhydrophenanthren-17-furyl-3ß-derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutischen Zusammensetzungen |
DE69306513T DE69306513T2 (de) | 1992-09-29 | 1993-09-22 | Neue kardioaktive Zyklopentaperhydrophenanthrene-17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta Derivate, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69306513D1 true DE69306513D1 (de) | 1997-01-23 |
DE69306513T2 DE69306513T2 (de) | 1997-05-15 |
Family
ID=6469153
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE4232656A Expired - Fee Related DE4232656C2 (de) | 1992-09-29 | 1992-09-29 | Cyclopentanperhydrophenanthren-17-furyl-3ß-derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutischen Zusammensetzungen |
DE69306513T Expired - Fee Related DE69306513T2 (de) | 1992-09-29 | 1993-09-22 | Neue kardioaktive Zyklopentaperhydrophenanthrene-17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta Derivate, ein Verfahren zu ihrer Herstellung und pharmazeutische Präparate davon |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE4232656A Expired - Fee Related DE4232656C2 (de) | 1992-09-29 | 1992-09-29 | Cyclopentanperhydrophenanthren-17-furyl-3ß-derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutischen Zusammensetzungen |
Country Status (9)
Country | Link |
---|---|
US (1) | US5521167A (de) |
EP (1) | EP0590489B1 (de) |
JP (1) | JPH06211893A (de) |
AT (1) | ATE146184T1 (de) |
DE (2) | DE4232656C2 (de) |
DK (1) | DK0590489T3 (de) |
ES (1) | ES2095542T3 (de) |
GR (1) | GR3021998T3 (de) |
HK (1) | HK1005879A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19633349A1 (de) * | 1996-08-19 | 1998-02-26 | Sigma Tau Ind Farmaceuti | Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten |
US6093389A (en) * | 1997-12-01 | 2000-07-25 | American Cyanamid Company | Methods and compositions for attracting and controlling termites |
US8084446B2 (en) | 2005-04-26 | 2011-12-27 | Eric Marchewitz | Use of DHEA derivatives for enhancing physical performance |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2938030A (en) * | 1956-10-03 | 1960-05-24 | Ciba Pharm Prod Inc | New steroids substituted by a heterocyclic nitrogen-containing ring in 17-position |
DE1227015B (de) * | 1963-01-23 | 1966-10-20 | Bayer Ag | Verfahren zur Herstellung von 3beta-Hydroxy-(bzw.-Acyloxy)-steroid-20-amidylhydrazonen der Pregnanreihe |
US3398138A (en) * | 1966-05-24 | 1968-08-20 | American Home Prod | Novel cardenolides and derivatives |
US3436390A (en) * | 1966-05-24 | 1969-04-01 | American Home Prod | 4,4-dihydroxy-2-butenoic acid lactones |
FR2414514A1 (fr) * | 1978-01-11 | 1979-08-10 | Roussel Uclaf | Nouveaux derives steroides 17aaryle ou aheteroaryle, leur procede de preparation et leur application comme medicament |
IE53463B1 (en) * | 1981-06-15 | 1988-11-23 | Akzo Nv | Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same |
US5380840A (en) * | 1985-09-12 | 1995-01-10 | The Upjohn Company | Triazinylpiperazinyl steroids |
GB8916636D0 (en) * | 1989-07-20 | 1989-09-06 | Erba Carlo Spa | Steroid ethers |
DE4221636C1 (de) * | 1992-07-01 | 1994-03-31 | Sigma Tau Ind Farmaceuti | Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate |
DE4227605C2 (de) * | 1992-08-20 | 1995-02-16 | Sigma Tau Ind Farmaceuti | 17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten |
US5252630A (en) * | 1992-10-15 | 1993-10-12 | Duke University | Antifouling coating and method for using same |
-
1992
- 1992-09-29 DE DE4232656A patent/DE4232656C2/de not_active Expired - Fee Related
-
1993
- 1993-09-22 AT AT93115247T patent/ATE146184T1/de active
- 1993-09-22 DE DE69306513T patent/DE69306513T2/de not_active Expired - Fee Related
- 1993-09-22 DK DK93115247.4T patent/DK0590489T3/da active
- 1993-09-22 ES ES93115247T patent/ES2095542T3/es not_active Expired - Lifetime
- 1993-09-22 EP EP93115247A patent/EP0590489B1/de not_active Expired - Lifetime
- 1993-09-29 US US08/128,128 patent/US5521167A/en not_active Expired - Fee Related
- 1993-09-29 JP JP5243360A patent/JPH06211893A/ja not_active Withdrawn
-
1996
- 1996-12-12 GR GR960402371T patent/GR3021998T3/el unknown
-
1998
- 1998-06-05 HK HK98104948A patent/HK1005879A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US5521167A (en) | 1996-05-28 |
HK1005879A1 (en) | 1999-01-29 |
DE4232656A1 (de) | 1994-03-31 |
JPH06211893A (ja) | 1994-08-02 |
ATE146184T1 (de) | 1996-12-15 |
EP0590489A2 (de) | 1994-04-06 |
DE69306513T2 (de) | 1997-05-15 |
DK0590489T3 (da) | 1996-12-30 |
DE4232656C2 (de) | 1995-01-12 |
ES2095542T3 (es) | 1997-02-16 |
EP0590489B1 (de) | 1996-12-11 |
EP0590489A3 (en) | 1994-06-29 |
GR3021998T3 (en) | 1997-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |