DE69231835T2 - Künstliche-Säuger-Chromosome - Google Patents

Künstliche-Säuger-Chromosome

Info

Publication number
DE69231835T2
DE69231835T2 DE69231835T DE69231835T DE69231835T2 DE 69231835 T2 DE69231835 T2 DE 69231835T2 DE 69231835 T DE69231835 T DE 69231835T DE 69231835 T DE69231835 T DE 69231835T DE 69231835 T2 DE69231835 T2 DE 69231835T2
Authority
DE
Germany
Prior art keywords
cell lines
chromosomes
centromeres
dna sequences
mammalian chromosomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69231835T
Other languages
English (en)
Other versions
DE69231835D1 (de
Inventor
Gyula Hadlaczky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOLOG RES CT OF HUNGARIAN
Original Assignee
BIOLOG RES CT OF HUNGARIAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOLOG RES CT OF HUNGARIAN filed Critical BIOLOG RES CT OF HUNGARIAN
Application granted granted Critical
Publication of DE69231835D1 publication Critical patent/DE69231835D1/de
Publication of DE69231835T2 publication Critical patent/DE69231835T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/166—Animal cells resulting from interspecies fusion
DE69231835T 1991-09-13 1992-09-14 Künstliche-Säuger-Chromosome Expired - Fee Related DE69231835T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/759,558 US5288625A (en) 1991-09-13 1991-09-13 Mammalian artificial chromosomes

Publications (2)

Publication Number Publication Date
DE69231835D1 DE69231835D1 (de) 2001-06-28
DE69231835T2 true DE69231835T2 (de) 2001-11-22

Family

ID=25056105

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231835T Expired - Fee Related DE69231835T2 (de) 1991-09-13 1992-09-14 Künstliche-Säuger-Chromosome

Country Status (6)

Country Link
US (1) US5288625A (de)
EP (1) EP0532050B1 (de)
JP (1) JP3456715B2 (de)
AT (1) ATE201450T1 (de)
CA (1) CA2078189C (de)
DE (1) DE69231835T2 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2042093C (en) * 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres
US6348353B1 (en) 1995-06-07 2002-02-19 Case Western Reserve University Artificial mammalian chromosome
US5869294A (en) * 1995-06-07 1999-02-09 Case Western Reserve University Method for stably cloning large repeating DNA sequences
US5695967A (en) * 1995-06-07 1997-12-09 Case Western Reserve University Method for stably cloning large repeating units of DNA
US6632976B1 (en) 1995-08-29 2003-10-14 Kirin Beer Kabushiki Kaisha Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene
US5721118A (en) * 1995-10-31 1998-02-24 The Regents Of The University Of California, San Diego Mammalian artificial chromosomes and methods of using same
US6133503A (en) * 1995-10-31 2000-10-17 The Regents Of The University Of California Mammalian artificial chromosomes and methods of using same
US20020160970A1 (en) * 1996-04-10 2002-10-31 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20030033617A1 (en) * 1996-04-10 2003-02-13 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6077697A (en) * 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
EP0928339B1 (de) 1996-08-26 2008-08-06 Chromo Research, Inc. Künstliche säuger chromosome
US7235716B2 (en) 1997-06-03 2007-06-26 Chromatin, Inc. Plant centromere compositions
US6972197B1 (en) 1999-03-18 2005-12-06 The University Of Chicago Plant chromosome compositions and methods
US7193128B2 (en) * 1997-06-03 2007-03-20 Chromatin, Inc. Methods for generating or increasing revenues from crops
WO1998055637A1 (en) * 1997-06-03 1998-12-10 Arch Development Corporation Plant artificial chromosome (plac) compositions and methods
US7119250B2 (en) * 1997-06-03 2006-10-10 The University Of Chicago Plant centromere compositions
US7227057B2 (en) 1997-06-03 2007-06-05 Chromatin, Inc. Plant centromere compositions
US6900012B1 (en) 1997-06-03 2005-05-31 The University Of Chicago Plant artificial chromosome compositions and methods
AU5217599A (en) 1998-07-27 2000-02-21 Genotypes, Inc. Automatic eukaryotic artificial chromosome vector
US7989202B1 (en) 1999-03-18 2011-08-02 The University Of Chicago Plant centromere compositions
US6475794B1 (en) * 1999-10-08 2002-11-05 The Johns Hopkins University Converting diploidy to haploidy for genetic diagnosis
US6399374B1 (en) * 1999-10-08 2002-06-04 The Johns Hopkins University Converting diploidy to haploidy for genetic diagnosis
JP4071622B2 (ja) * 2000-09-28 2008-04-02 バイオリジナル フード アンド サイエンス コーポレーション 脂肪酸不飽和化酵素ファミリーのメンバーであるｆａｄ４、ｆａｄ５、ｆａｄ５−２およびｆａｄ６、ならびにそれらの使用方法
US6936469B2 (en) 2001-03-22 2005-08-30 Chromos Molecular Systems Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US20030186390A1 (en) * 2001-03-22 2003-10-02 De Jong Gary Methods for delivering nucleic acid molecules into cells and assessment thereof
US7294511B2 (en) 2001-03-22 2007-11-13 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US20050287647A9 (en) * 2001-05-30 2005-12-29 Carl Perez Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes
NZ545697A (en) * 2001-05-30 2008-06-30 Glaxo Group Ltd A lambda-intR mutein comprising a glutamic acid to arginine change at position 174 of Wt lambda-intR
US7335470B2 (en) 2001-10-12 2008-02-26 Perkinelmer, Las, Inc. Compilations of nucleic acids and arrays and methods of using them
US7439346B2 (en) * 2001-10-12 2008-10-21 Perkinelmer Las Inc. Nucleic acids arrays and methods of use therefor
US7330851B2 (en) * 2003-08-18 2008-02-12 Eaglehawk, Limited Data security through dissembly of data elements or connections between elements
AU2004286845A1 (en) * 2003-10-30 2005-05-19 Tufts-New England Medical Center Prenatal diagnosis using cell-free fetal DNA in amniotic fluid
CA2557644C (en) * 2004-02-23 2016-05-24 Chromatin, Inc. Plants modified with mini-chromosomes
US20060174364A1 (en) * 2004-03-01 2006-08-03 Avigenics, Inc. Artificial chromosomes and transchromosomic avians
EP2527456B1 (de) 2004-10-22 2018-05-16 Revivicor Inc. Transgenschweine ohne endogene leichte Kette von Immunglobulin
EP1929019A2 (de) * 2005-09-08 2008-06-11 Chromatin, Inc. Mit minichromosomen modifizierte pflanzen
WO2007084767A2 (en) * 2006-01-20 2007-07-26 University Of South Florida Methods for profiling transcriptosomes
US8614089B2 (en) * 2007-03-15 2013-12-24 Chromatin, Inc. Centromere sequences and minichromosomes
ES2548377T3 (es) 2008-10-27 2015-10-16 Revivicor, Inc. Ungulados inmunodeprimidos
AU2010275448B2 (en) 2009-07-23 2014-03-06 Chromatin, Inc. Sorghum centromere sequences and minichromosomes
HU230368B1 (hu) 2012-11-16 2016-03-29 Magyar Tudományos Akadémia Szegedi Biológiai Kutatóközpont Új módszer az emlős mesterséges kromoszóma több génnel való feltöltésére
JP2019513396A (ja) 2016-04-12 2019-05-30 シンプロイド バイオテック エルエルシーＳｙｎｐｌｏｉｄ Ｂｉｏｔｅｋ，Ｌｌｃ 遺伝子調節システムを有する合成染色体の作成方法及びその使用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608339A (en) * 1983-10-25 1986-08-26 Yoakum George H Protoplast fusion method for high-frequency DNA transfection in human cells
US4970162A (en) * 1985-11-13 1990-11-13 The United States Of America As Represented By The Department Of Health And Human Services Human-mouse hybrid cell line expressing monocyte-macrophage properties
US4935350A (en) * 1985-11-18 1990-06-19 Amgen Materials and methods for controlling plasmid copy number and stability
FR2593827B1 (fr) * 1986-01-31 1989-12-22 Inst Nat Sante Rech Med Fragments d'adn utilisables dans des vecteurs pour le maintien hereditaire de genes etrangers a l'etat autonome dans des animaux transgeniques, procede pour leur obtention et applications biologiques
CA2006011A1 (en) * 1988-12-21 1990-06-21 Cecilia Lo Transgenic organisms and cells and methods of producing transgenic organisms and cells
CA2042093C (en) * 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres

Also Published As

Publication number Publication date
US5288625A (en) 1994-02-22
CA2078189C (en) 1999-12-14
EP0532050A3 (en) 1993-07-21
DE69231835D1 (de) 2001-06-28
JPH07177881A (ja) 1995-07-18
EP0532050A2 (de) 1993-03-17
EP0532050B1 (de) 2001-05-23
JP3456715B2 (ja) 2003-10-14
ATE201450T1 (de) 2001-06-15
CA2078189A1 (en) 1993-03-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee