ATE201450T1 - Künstliche-säuger-chromosome - Google Patents
Künstliche-säuger-chromosomeInfo
- Publication number
- ATE201450T1 ATE201450T1 AT92115694T AT92115694T ATE201450T1 AT E201450 T1 ATE201450 T1 AT E201450T1 AT 92115694 T AT92115694 T AT 92115694T AT 92115694 T AT92115694 T AT 92115694T AT E201450 T1 ATE201450 T1 AT E201450T1
- Authority
- AT
- Austria
- Prior art keywords
- chromosomes
- cell lines
- centromeres
- dna sequences
- human dna
- Prior art date
Links
- 210000000349 chromosome Anatomy 0.000 title abstract 4
- 241000124008 Mammalia Species 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 4
- 210000002230 centromere Anatomy 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/166—Animal cells resulting from interspecies fusion
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/759,558 US5288625A (en) | 1991-09-13 | 1991-09-13 | Mammalian artificial chromosomes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201450T1 true ATE201450T1 (de) | 2001-06-15 |
Family
ID=25056105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92115694T ATE201450T1 (de) | 1991-09-13 | 1992-09-14 | Künstliche-säuger-chromosome |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5288625A (de) |
| EP (1) | EP0532050B1 (de) |
| JP (1) | JP3456715B2 (de) |
| AT (1) | ATE201450T1 (de) |
| CA (1) | CA2078189C (de) |
| DE (1) | DE69231835T2 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2042093C (en) * | 1990-05-09 | 2002-12-24 | Gyula Hadlaczky | Cell line carrying an excess of mammalian centromeres |
| US6348353B1 (en) | 1995-06-07 | 2002-02-19 | Case Western Reserve University | Artificial mammalian chromosome |
| US5695967A (en) * | 1995-06-07 | 1997-12-09 | Case Western Reserve University | Method for stably cloning large repeating units of DNA |
| US5869294A (en) * | 1995-06-07 | 1999-02-09 | Case Western Reserve University | Method for stably cloning large repeating DNA sequences |
| US6632976B1 (en) | 1995-08-29 | 2003-10-14 | Kirin Beer Kabushiki Kaisha | Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene |
| US5721118A (en) * | 1995-10-31 | 1998-02-24 | The Regents Of The University Of California, San Diego | Mammalian artificial chromosomes and methods of using same |
| US6133503A (en) * | 1995-10-31 | 2000-10-17 | The Regents Of The University Of California | Mammalian artificial chromosomes and methods of using same |
| US6077697A (en) | 1996-04-10 | 2000-06-20 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US20020160970A1 (en) * | 1996-04-10 | 2002-10-31 | Gyula Hadlaczky | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US20030033617A1 (en) * | 1996-04-10 | 2003-02-13 | Gyula Hadlaczky | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| US6025155A (en) * | 1996-04-10 | 2000-02-15 | Chromos Molecular Systems, Inc. | Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes |
| EP0928339B1 (de) | 1996-08-26 | 2008-08-06 | Chromo Research, Inc. | Künstliche säuger chromosome |
| EP2000538A3 (de) * | 1997-06-03 | 2010-06-23 | The University of Chicago | Verbindungen aus künstlichen Pflanzenchromosomen und ihre Verwendung |
| US6972197B1 (en) | 1999-03-18 | 2005-12-06 | The University Of Chicago | Plant chromosome compositions and methods |
| US7227057B2 (en) | 1997-06-03 | 2007-06-05 | Chromatin, Inc. | Plant centromere compositions |
| US6900012B1 (en) * | 1997-06-03 | 2005-05-31 | The University Of Chicago | Plant artificial chromosome compositions and methods |
| US7235716B2 (en) | 1997-06-03 | 2007-06-26 | Chromatin, Inc. | Plant centromere compositions |
| US7119250B2 (en) * | 1997-06-03 | 2006-10-10 | The University Of Chicago | Plant centromere compositions |
| US7193128B2 (en) * | 1997-06-03 | 2007-03-20 | Chromatin, Inc. | Methods for generating or increasing revenues from crops |
| US6670154B1 (en) | 1998-07-27 | 2003-12-30 | Ronald A. Hitzeman | Automatic eukaryotic artificial chromosome vector |
| US7989202B1 (en) | 1999-03-18 | 2011-08-02 | The University Of Chicago | Plant centromere compositions |
| US6475794B1 (en) * | 1999-10-08 | 2002-11-05 | The Johns Hopkins University | Converting diploidy to haploidy for genetic diagnosis |
| US6399374B1 (en) * | 1999-10-08 | 2002-06-04 | The Johns Hopkins University | Converting diploidy to haploidy for genetic diagnosis |
| CN101845446B (zh) * | 2000-09-28 | 2016-01-20 | 生物源食物及科学公司 | 脂肪酸去饱和酶家族成员fad4、fad5、fad5-2和fad6及它们的应用 |
| US20030186390A1 (en) * | 2001-03-22 | 2003-10-02 | De Jong Gary | Methods for delivering nucleic acid molecules into cells and assessment thereof |
| US7294511B2 (en) | 2001-03-22 | 2007-11-13 | Chromos Molecular Systems, Inc. | Methods for delivering nucleic acid molecules into cells and assessment thereof |
| US6936469B2 (en) | 2001-03-22 | 2005-08-30 | Chromos Molecular Systems Inc. | Methods for delivering nucleic acid molecules into cells and assessment thereof |
| US20030119104A1 (en) * | 2001-05-30 | 2003-06-26 | Edward Perkins | Chromosome-based platforms |
| MXPA03010967A (es) * | 2001-05-30 | 2004-10-28 | Chromos Molecular Systems Inc | Cromosomas artificiales de plantas, usos de los mismos y metodos para preparar cromosomas artificiales de plantas. |
| WO2003091426A1 (en) | 2001-10-12 | 2003-11-06 | Spectral Genomics, Inc. | Compilations of nucleic acids and arrays and methods of using them |
| US7439346B2 (en) * | 2001-10-12 | 2008-10-21 | Perkinelmer Las Inc. | Nucleic acids arrays and methods of use therefor |
| US7330851B2 (en) * | 2003-08-18 | 2008-02-12 | Eaglehawk, Limited | Data security through dissembly of data elements or connections between elements |
| WO2005044086A2 (en) * | 2003-10-30 | 2005-05-19 | Tufts-New England Medical Center | Prenatal diagnosis using cell-free fetal dna in amniotic fluid |
| CA2557644C (en) * | 2004-02-23 | 2016-05-24 | Chromatin, Inc. | Plants modified with mini-chromosomes |
| US20060174364A1 (en) * | 2004-03-01 | 2006-08-03 | Avigenics, Inc. | Artificial chromosomes and transchromosomic avians |
| EP1811832A4 (de) | 2004-10-22 | 2009-12-30 | Revivicor Inc | Huftiere mit gentechnisch veränderten immunsystemen |
| AU2006287553A1 (en) * | 2005-09-08 | 2007-03-15 | Chromatin, Inc. | Plants modified with mini-chromosomes |
| WO2007084767A2 (en) * | 2006-01-20 | 2007-07-26 | University Of South Florida | Methods for profiling transcriptosomes |
| US8614089B2 (en) * | 2007-03-15 | 2013-12-24 | Chromatin, Inc. | Centromere sequences and minichromosomes |
| EP2348827B1 (de) | 2008-10-27 | 2015-07-01 | Revivicor, Inc. | Immunsupprimierte huftiere |
| WO2011011693A1 (en) | 2009-07-23 | 2011-01-27 | Chromatin, Inc. | Sorghum centromere sequences and minichromosomes |
| HU230368B1 (hu) | 2012-11-16 | 2016-03-29 | Magyar Tudományos Akadémia Szegedi Biológiai Kutatóközpont | Új módszer az emlős mesterséges kromoszóma több génnel való feltöltésére |
| EP4495248A3 (de) | 2016-04-12 | 2025-04-02 | CarryGenes Bioengineering, LLC | Verfahren zur erzeugung synthetischer chromosomen mit genregulatorischen systemen und verwendungen davon |
| AU2017249321B2 (en) | 2016-04-12 | 2024-05-23 | CarryGenes Bioengineering | Methods for creating synthetic chromosomes expressing biosynthetic pathways and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4608339A (en) * | 1983-10-25 | 1986-08-26 | Yoakum George H | Protoplast fusion method for high-frequency DNA transfection in human cells |
| US4970162A (en) * | 1985-11-13 | 1990-11-13 | The United States Of America As Represented By The Department Of Health And Human Services | Human-mouse hybrid cell line expressing monocyte-macrophage properties |
| US4935350A (en) * | 1985-11-18 | 1990-06-19 | Amgen | Materials and methods for controlling plasmid copy number and stability |
| FR2593827B1 (fr) * | 1986-01-31 | 1989-12-22 | Inst Nat Sante Rech Med | Fragments d'adn utilisables dans des vecteurs pour le maintien hereditaire de genes etrangers a l'etat autonome dans des animaux transgeniques, procede pour leur obtention et applications biologiques |
| CA2006011A1 (en) * | 1988-12-21 | 1990-06-21 | Cecilia Lo | Transgenic organisms and cells and methods of producing transgenic organisms and cells |
| CA2042093C (en) * | 1990-05-09 | 2002-12-24 | Gyula Hadlaczky | Cell line carrying an excess of mammalian centromeres |
-
1991
- 1991-09-13 US US07/759,558 patent/US5288625A/en not_active Expired - Fee Related
-
1992
- 1992-09-14 CA CA002078189A patent/CA2078189C/en not_active Expired - Fee Related
- 1992-09-14 JP JP24520692A patent/JP3456715B2/ja not_active Expired - Fee Related
- 1992-09-14 DE DE69231835T patent/DE69231835T2/de not_active Expired - Fee Related
- 1992-09-14 AT AT92115694T patent/ATE201450T1/de not_active IP Right Cessation
- 1992-09-14 EP EP92115694A patent/EP0532050B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0532050A2 (de) | 1993-03-17 |
| EP0532050B1 (de) | 2001-05-23 |
| EP0532050A3 (en) | 1993-07-21 |
| JPH07177881A (ja) | 1995-07-18 |
| DE69231835T2 (de) | 2001-11-22 |
| DE69231835D1 (de) | 2001-06-28 |
| CA2078189C (en) | 1999-12-14 |
| JP3456715B2 (ja) | 2003-10-14 |
| US5288625A (en) | 1994-02-22 |
| CA2078189A1 (en) | 1993-03-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE201450T1 (de) | Künstliche-säuger-chromosome | |
| ATE250134T1 (de) | Säuger-zentromere mit menschlicher dns, die mit einem dominanten marker assoziiert sind | |
| ATE403733T1 (de) | Künstliche säuger chromosome | |
| Charlesworth et al. | Population dynamics of the segregation distorter polymorphism of Drosophila melanogaster | |
| SG48760A1 (en) | Generation of xenogenetic antibodies | |
| DK0791058T3 (da) | Anvendelse af en nukleotidsekvens, der koder for enzymet I-SCEI | |
| ATE198355T1 (de) | Alpha-amidierende enzymzusammensetzungen und verfahren zu deren herstellung und verwendung | |
| ATE455179T1 (de) | Humanes chromosomfragment und ein vektor, der dies enthält | |
| DK0843961T3 (da) | Kimærisk mus og fremgangsmåde til at producere samme | |
| EP0463151A4 (en) | Generation of xenogeneic antibodies | |
| AU7833494A (en) | Enhanced expression in plants using non-translated leader sequences | |
| ATE120486T1 (de) | Vektor zur integrationsstellenunabhängigen genexpression in säugetier-wirtszellen. | |
| DE3575576D1 (de) | Mikroinjektionstechnik fuer pflanzenzellen. | |
| DK224185D0 (da) | Vektor til inkorporering i gaercellers chromosomer | |
| MX9805507A (es) | Composicion para la transfeccion de celulas eucarioticas superiores. | |
| FI962268A0 (fi) | Homologinen, rekombinanttinen vasta-aineilmentämisjärjestelmä rottien tai hiirien soluille | |
| SE8104700L (sv) | Eukaryotiskt autonomt replikerande segment | |
| EP0569678A3 (de) | Mit MHC-Genen doppelt transfizierte Zellen als Impfstoffe zur Immunoprevention von Tumormetastasen. | |
| Lewin | The genetics of algae | |
| CO4810249A1 (es) | Metodo para la seleccion de plantas transformadas . | |
| DE69941451D1 (de) | Verfahren zur unterdrückung der genexpression in pflanzen | |
| DK0596881T3 (da) | Ekspression i ikke-tumurale humane lymofoblastoider med en integrativ vektor | |
| IL97048A0 (en) | Bioluminescence assay for gene expression in growing mammalian cells | |
| NO974367D0 (no) | Vektorer samt fremgangsmåter for gen-ekspresjon i pattedyrceller | |
| ATE259421T1 (de) | Dna-virus-vektoren und verfahren zu ihrer herstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |